Erratum to "Plasma Proteomic Markers of Interleukin-1β Pathway Associated with Incident Age-Related Macular Degeneration in Persons with AIDS" [Ophthalmol Sci. 2025;5:100794] - PubMed (original) (raw)

Published Erratum

Peter W Hunt et al. Ophthalmol Sci. 2025.

Abstract

[This corrects the article DOI: 10.1016/j.xops.2025.100794.].

© 2025 by the American Academy of Ophthalmologyé.

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Figures

Figure 1

Figure 1

Plasma inflammatory proteins and the IL-1β pathway associated with incident AMD in treated HIV. A, The negative log10 P value is plotted by the adjusted odds of AMD for each twofold increase in Npx value for each plasma protein in the Olink Inflammation Explore panel. Benjamini–Hochberg FDR Q values <0.05 are colored in purple, and <0.01 in red. B, The protein network map (using the STRING database) of all proteins significantly associated with AMD (Q < 0.05) is shown, labeling each significant protein with color depicting the adjusted odds ratio (positive association in red, negative association in blue); nonsignificant proteins are unlabeled in light gray. C, Proteomic pathways associated with incident AMD by gene ontology pathway enrichment analysis are depicted, with the normalized enrichment score on the x-axis and significance level denoted by color. D, The adjusted odds ratios for all proteins represented in the IL-1β pathway are plotted in a protein network map, with the color of each dot denoting the odds ratio and the size representing the significance levels. Proteins significant at the Q < 0.05 level are circled in green. AMD = age-related macular degeneration; FDR = false discovery rate; HIV = human immunodeficiency virus; IL = interleukin; NPx = normalized protein expression.

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