Animal models of schizophrenia - PubMed (original) (raw)

Comparative Study

. 1981 Apr;138(4):478-83.

doi: 10.1176/ajp.138.4.478.

Comparative Study

Animal models of schizophrenia

W T McKinney et al. Am J Psychiatry. 1981 Apr.

Abstract

The authors review some general issues concerning the development and use of animal models of schizophrenia and present a summary of the criteria necessary for validating models. They also describe some of the major attempts at creating animal models of schizophrenia, including drug and nondrug methods. They comment on the etiologic, phenomenologic, and treatment relevance of the various systems and suggest approaches that might produce improved animal models of schizophrenia.

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