The operator-binding domain of lambda repressor: structure and DNA recognition - PubMed (original) (raw)

. 1982 Jul 29;298(5873):443-7.

doi: 10.1038/298443a0.

• PMID: 7088190
• DOI: 10.1038/298443a0

The operator-binding domain of lambda repressor: structure and DNA recognition

C O Pabo et al. Nature. 1982.

Abstract

The structure of the operator-binding domain of the lambda repressor has been determined at 3.2 A resolution. This domain contains an extended N-terminal arm and five alpha-helices. Model-building studies of the repressor-operator complex suggest that alpha-helices, especially the N-terminal parts of these helices, may provide a useful surface for protein-DNA interactions.

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