A randomized controlled trial of vitamin C in the prevention and amelioration of the common cold - PubMed (original) (raw)
Clinical Trial
A randomized controlled trial of vitamin C in the prevention and amelioration of the common cold
P C Elwood et al. Br J Prev Soc Med. 1976 Sep.
Abstract
A randomized controlled trial of the effect of 1 g ascorbic acid per day in the prevention of the common cold was conducted on 688 adult women. There is evidence of a small reduction by vitamin C in the mean number of chest colds, but no evidence of any effect on simple colds. The existence of a subgroup of vulnerable women in the community who benefit from vitamin C was considered but further examination of the data gives no support to this conclusion.
Similar articles
- Large-scale trials of vitamin C in the prevention and treatment of "colds".
Anderson TW. Anderson TW. Acta Vitaminol Enzymol. 1974;28(1-4):99-100. Acta Vitaminol Enzymol. 1974. PMID: 4615592 Clinical Trial. No abstract available. - Vitamin C and colds.
Wilson CW, Loh HS. Wilson CW, et al. Lancet. 1973 May 12;1(7811):1058-9. doi: 10.1016/s0140-6736(73)90692-2. Lancet. 1973. PMID: 4122133 Clinical Trial. No abstract available. - Effects of ascorbic acid on the common cold. An evaluation of the evidence.
Chalmers TC. Chalmers TC. Am J Med. 1975 Apr;58(4):532-6. doi: 10.1016/0002-9343(75)90127-8. Am J Med. 1975. PMID: 1092164 Review. - The significance of the evidence about ascorbic acid and the common cold.
Pauling L. Pauling L. Proc Natl Acad Sci U S A. 1971 Nov;68(11):2678-81. doi: 10.1073/pnas.68.11.2678. Proc Natl Acad Sci U S A. 1971. PMID: 4941984 Free PMC article. Review. - A trial of ascorbic acid in the treatment of the common cold.
Tyrrell DA, Craig JW, Meada TW, White T. Tyrrell DA, et al. Br J Prev Soc Med. 1977 Sep;31(3):189-91. doi: 10.1136/jech.31.3.189. Br J Prev Soc Med. 1977. PMID: 338079 Free PMC article. Clinical Trial.
Cited by
- Dietary Sources, Bioavailability, and Functions of Ascorbic Acid (Vitamin C) and Its Role in the Common Cold, Tissue Healing, and Iron Metabolism.
Bhoot HR, Zamwar UM, Chakole S, Anjankar A. Bhoot HR, et al. Cureus. 2023 Nov 23;15(11):e49308. doi: 10.7759/cureus.49308. eCollection 2023 Nov. Cureus. 2023. PMID: 38146585 Free PMC article. Review. - Vitamin C reduces the severity of common colds: a meta-analysis.
Hemilä H, Chalker E. Hemilä H, et al. BMC Public Health. 2023 Dec 11;23(1):2468. doi: 10.1186/s12889-023-17229-8. BMC Public Health. 2023. PMID: 38082300 Free PMC article. Review. - Vitamin C: From nutrition to oxygen sensing and epigenetics.
Kietzmann T. Kietzmann T. Redox Biol. 2023 Jul;63:102753. doi: 10.1016/j.redox.2023.102753. Epub 2023 May 27. Redox Biol. 2023. PMID: 37263060 Free PMC article. - Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
Abioye AI, Bromage S, Fawzi W. Abioye AI, et al. BMJ Glob Health. 2021 Jan;6(1):e003176. doi: 10.1136/bmjgh-2020-003176. BMJ Glob Health. 2021. PMID: 33472840 Free PMC article. - Vitamin C in disease prevention and cure: an overview.
Chambial S, Dwivedi S, Shukla KK, John PJ, Sharma P. Chambial S, et al. Indian J Clin Biochem. 2013 Oct;28(4):314-28. doi: 10.1007/s12291-013-0375-3. Epub 2013 Sep 1. Indian J Clin Biochem. 2013. PMID: 24426232 Free PMC article. Review.
References
- Helv Med Acta. 1961 Jan;28:63-8 - PubMed
- Lancet. 1972 Jun 24;1(7765):1401-2 - PubMed
- Lancet. 1973 Mar 24;1(7804):638-41 - PubMed
- Can Med Assoc J. 1975 Apr 5;112(7):823-6 - PubMed
- JAMA. 1975 Mar 10;231(10):1038-42 - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources