The malaria parasite, Plasmodium falciparum, increases the frequency of multiple feeding of its mosquito vector, Anopheles gambiae - PubMed (original) (raw)

The malaria parasite, Plasmodium falciparum, increases the frequency of multiple feeding of its mosquito vector, Anopheles gambiae

J C Koella et al. Proc Biol Sci. 1998.

Abstract

It has often been suggested that vector-borne parasites alter their vector's feeding behaviour to increase their transmission, but these claims are often based on laboratory studies and lack rigorous testing in a natural situation. We show in this field study that the malaria parasite, Plasmodium falciparum, alters the blood-feeding behaviour of its mosquito vector, Anopheles gambiae s.l., in two ways. First, mosquitoes infected with sporozoited, the parasite stage that is transmitted from the mosquito to a human, took up larger blood meals than uninfected mosquitoes. Whereas 72% of the uninfected mosquitoes had obtained a full blood meal, 82% of the infected ones had engorged fully. Second, mosquitoes harbouring sporozoites were more likely to bite several people per night. Twenty-two per cent of the infected mosquitoes, but only 10% of the uninfected mosquitoes, contained blood from at least two people. We conclude that the observed changes in blood-feeding behaviour allow the parasite to spread more rapidly among human hosts, and thus confirm that the parasite manipulates the mosquito to increase its own transmission.

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References

    1. Am J Trop Med Hyg. 1978 Jul;27(4):827-31 -PubMed
    1. Parasitology. 1997 Apr;114 ( Pt 4):325-31 -PubMed
    1. J Insect Physiol. 1979;25(7):583-5 -PubMed
    1. Am J Trop Med Hyg. 1980 Nov;29(6):1460-4 -PubMed
    1. Am J Trop Med Hyg. 1981 Sep;30(5):948-51 -PubMed

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