The GnRH promoter: target of transcription factors, hormones, and signaling pathways - PubMed (original) (raw)

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The GnRH promoter: target of transcription factors, hormones, and signaling pathways

S B Nelson et al. Mol Cell Endocrinol. 1998.

Abstract

Gonadotropin-releasing hormone (GnRH) is essential for normal reproductive maturation and function. We present a review of the known mechanisms of hypothalamic GnRH transcriptional control through the conserved GnRH promoter. Understanding this promoter region will allow us to comprehend better the complexities of the hypothalamic pituitary-gonadal axis.

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