Associations between weight change since 20 years... : International Journal of Obesity (original) (raw)

Associations between weight change since 20 years of age and sleep-disordered breathing among male truck drivers

• R Cui
• T Tanigawa
• H Nakano
• S Sakurai
• K Yamagishi
• T Ohira
• H Iso

International Journal of Obesity

33

(

12

)

:p

1396

-

1401

,

December 2009

.

| DOI: 10.1038/ijo.2009.192

Background:

Limited evidence for association of weight gain with sleep-disordered breathing (SDB) has been produced for Asian populations whose body mass index (BMI) levels are lower than in western countries.

Objective:

The aim of this study was to examine weight change since 20 years of age and risk of SDB among Japanese.

Design:

Retrospective cohort study.

Subjects:

This study includes a large sample of 5320 male Japanese truck drivers aged 30–69 years.

Measurements:

The respiratory disturbance index (RDI) was selected as an indicator of SDB, and it was estimated with a onenight sleep test using an airflow monitor, and the Epworth Sleepiness Scale (ESS) was used to estimate excessive daytime sleepiness.

Results:

Respiratory disturbance and sleepiness were more prevalent among men with BMI of 25.0–29.9 and ≥30.0 kg/m2 than among those with BMI of 18.5–24.9; multivariable odds ratios (ORs) were 1.8(1.5–2.0), P<0.001 and 4.4(3.5–5.5), P<0.001 for RDI ≥10, and 1.2(0.9–1.4), _P_=0.18 and 1.5(1.1–2.1), _P_=0.02 for ESS ≥11, respectively. Compared with men showing BMI changes within ±1.0, the respective multivariable ORs for those with BMI changes of 3.0–4.9 and ≥5.0 were 1.4(1.2–1.6), P<0.001 and 2.4(2.0–2.9), P<0.001 for RDI ≥10, and 1.2(0.9–1.6), _P_=0.22 and 2.0(1.5–2.6), P<0.001 for ESS ≥11. The corresponding ORs for weight gain of ≥10.0 kg compared with weight change less than ±5.0 kg were 2.0(1.7–2.4), P<0.001 for RDI ≥10 and 1.5(1.2–2.0), _P_=0.002 for ESS ≥11. Similar trends were observed for RDI ≥20.

Conclusion:

Our results suggest that an increase in BMI of ≥5 kg/m2 or weight gain of ≥10 kg is a risk factor for SDB and excessive daytime sleepiness among Japanese truck drivers.