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The Primary Care Companionfor CNS Disorders
Advancing primary care with essential peer-reviewed research and insights into CNS disorders
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Case Report
Catatonia Associated With Post-Acute COVID-19 in a Young Child
January 9, 2025
A 4-year-old girl with high-functioning autism spectrum disorder experienced catatonia associated with the post-acute phase of SARS-CoV-2 infection.
Andrew Van Pay, Sarah Mohiuddin, Neera Ghaziuddin
PCC
Case Report
Sodium Valproate–Associated Psoriasis
January 9, 2025
The authors present a rare case of exacerbation of psoriasiform eruptions in a patient who was prescribed sodium valproate for seizures.
Anusha Aggarwal, Neeti Kumari, Amrit Pattojoshi, et al
PCC
Case Report
Treating Trichotillomania Via Tele-Based Habit Reversal Therapy
January 7, 2025
The authors present a case of trichotillomania in a patient who was managed via telepsychiatry-based habit reversal therapy during the COVID-19 pandemic.
Rika Rijal, Himani Adarsh, Nidhi Chauhan
PCC
Case Report
Broad Differential Diagnoses in a Case of Catatonia
January 3, 2025
This case presents a complex clinical scenario in which no single diagnosis fully accounted for the presenting symptoms.
Chin Kuo, Eun K. Hwang, Sara V. Carlini, et al
PCC
Rounds in the General Hospital
Focal Impaired Awareness Seizures: Evaluation and Management
January 3, 2025
Focal impaired awareness seizures can look like other psychiatric, neurological, and medical presentations, and due to the changes in affect, behavior, and cognition, are often misdiagnosed as a primary…
Caitlin Adams, Lara Basovic, Adriana Cantos, et al
PCC
Case Report
Antipsychotic-Induced Lingual Dystonia With Bradycardia
December 26, 2024
The authors present a rare case of antipsychotic-induced lingual dystonia that led to hemodynamic changes in a 15-year-old boy.
Diveesha Munipati, Sai K. Tikka, Barikar C. Malathesh, et al
Vol 26 • 2024 • Number 6
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Narrative Review Dextromethorphan-Quinidine for Agitation in Dementia Original Research Psychiatric Comorbidities in Adolescents With Polycystic Ovary Syndrome Original Research Intervention to Enhance Mental Health Competency Original Research Evolution of Treatment Modalities for PTSD Rounds in the General Hospital Etiology, Prevention, and Management of TD Rounds in the General Hospital Comorbid Bipolar Disorder and PTSD
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Rounds in the General Hospital Rounds from Banner Alzheimer's Institute
Original Research
PCC
Original Research
Psychological Resilience of Mental Health Workers During the Russia-Ukraine War
October 22, 2024
Interventions that bolster social connectedness, meaning in life, and optimism may help promote psychological resilience among mental health workers exposed to ongoing war-related and work-related stressors.
Hun Kang, Ian C. Fischer, Viktor Vus, et al
PCC
Original Research
Relationship Between Social Isolation and Substance Abuse
September 24, 2024
This study highlights the connection between social isolation and substance use disorder, emphasizing the need to address social isolation as a public health issue.
Rupak Desai, Sulaiman Karim, Jasmin Freeborn, et al
PCC
Original Research
Childhood Separation Anxiety Disorder and Panic Disorder
September 17, 2024
The respiratory subtype of panic disorder demonstrated a stronger association with childhood separation anxiety disorder when compared to the nonrespiratory subtype.
Mariana Costa do Cabo, Julio Cezar Albuquerque da Costa, Antonio Egidio Nardi, et al
Review Articles
PCC
Narrative Review
Improving Collaboration Between Neuropsychology and Primary Care
October 31, 2024
Collaboration between neuropsychologists and physicians significantly improves patient care by enhancing diagnostic precision and treatment planning. Read on to find out more.
Lynn A. Schaefer, Thomas J. Farrer, Dennis J. Dowling
PCC
Narrative Review
Understanding the Child and Adolescent Mental Health Crisis
October 24, 2024
The authors delve into current mental health challenges facing children and youth, examining perspectives from both pre-pandemic and pandemic periods.
Mayank Gupta, Kristie Ladegard, Nihit Gupta, et al
PCC
Narrative Review
Management of Sleep Disturbances in Veterans Following Mild TBI
September 12, 2024
The authors developed an evidence- and consensus-based clinical recommendation regarding primary care management of insufficient and disturbed sleep associated with concussion/mild traumatic brain injury in service members and veterans.
Joanne M. Gold, Amanda L. Gano, Gary L. McKinney, et al
PCC
Narrative Review
Management of ADHD in Adolescents and Young Adults
August 6, 2024
Drawing on their clinical experiences of implementing evidence-based guidelines and feedback from patients, the authors describe innovative strategies and solutions for improving the management of ADHD in adolescents and…
Tom Janzen, Samuel Chang, Geraldine Farrelly
PCC
Narrative Review
Tech Gaming Designs, Neurodevelopmental Vulnerabilities, and Internet Gaming Disorder Risk
July 23, 2024
The authors review the relevant research in the field of internet gaming disorder and provide an approach to identification and management.
Maneesh Chidambaram, Mayank Gupta, Nihit Gupta
PCC
Narrative Review
Alternative Treatment for Agitation in Schizophrenia and Bipolar Disorder
January 30, 2024
While oral and intramuscular formulations of pharmacologic agents continue to be commonly used to treat acute agitation, novel agents with alternative routes of delivery are becoming available.
Leslie Citrome, Christoph U. Correll, Luis San, et al
Rounds in the General Hospital
PCC
Rounds in the General Hospital
Treatment of Pain in the Context of Alcohol and Substance Use Disorders
October 17, 2024
When prescribing opioids for pain, prescription monitoring programs should be checked, regular urine toxicology screening should be conducted, and patients with an opioid use disorder should receive FDA-approved medication…
Sofia E. Matta, Olga Terechin, Rene M. Lento, et al
PCC
Rounds in the General Hospital
Talking to Your Patients About Psychedelics
October 15, 2024
Given the precipitous increase in both scientific publications and public interest in psychedelics, clinicians should learn more about how they work, what they might work for, and what their…
Franklin King IV, Acile Nahlawi, Theodore A. Stern
PCC
Rounds in the General Hospital
Clozapine: Its Use and Monitoring
July 30, 2024
The authors provide the latest information on clozapine use, including when your patients should receive or avoid taking it, what laboratory tests are required before and during administration, and…
Desta S. Lissanu, Chirag M. Vyas, Carol S. Lim, et al
PCC
Rounds in the General Hospital
Pharmacologic Management of TBI
July 16, 2024
Cognitive complaints, including difficulties with attention, concentration, and memory, are common in patients post-TBI; however, many medications have been studied in the treatment of cognition after TBI. Read on…
Sofia E. Matta, Christina LaCroix, Kaloyan Tanev, et al
PCC
Rounds in the General Hospital
Evaluation and Management of Treatment-Resistant Schizophrenia
July 2, 2024
If you have ever been uncertain about how to evaluate patients with a chronic psychotic illness or struggled over how best to manage treatment-resistant schizophrenia, then this case vignette…
PCC
Rounds in the General Hospital
Neuropsychiatric Complications of Hypervitaminosis D
June 13, 2024
A 28-year-old man presented to the emergency department with severe agitation, insomnia, weakness, constipation, and muscle jerks after nonsuicidal overdosing of vitamin D.
Case Reports
PCC
Case Report
Cyberbullying and Adolescent Mental Health
December 26, 2024
Two patients admitted to an inpatient psychiatric unit for suicidality cited interactions with users on the messaging app Discord as a significant stressor contributing to their presentation.
Tyler J. Thompson, Sahil Munjal
PCC
Case Report
Unexpected Hypersensitivity to Bupropion
December 5, 2024
A 33-year-old man with a history of depression presented to the emergency department with a rash 3 weeks after starting bupropion.
Samuel Bucek, Christopher Conquest, Priya Srivastava, et al
PCC
Case Report
Pindolol for Treatment-Refractory Panic Disorder
November 28, 2024
A patient with treatment-resistant panic disorder experienced a significant reduction in the frequency and severity of his attacks after pindolol treatment.
Melissa Vaz-Ayes, Bernard Sarmiento, Matthew Gunther, et al
PCC
Case Report
Recurrent Catatonia Following Hypothyroidism
November 26, 2024
The authors present the case of a 41-year-old woman with schizophrenia, in whom hypothyroidism and recurrent catatonia appear to be linked.
Vincent Zhang, Anmol Dhingra, Sabeeha Hussain, et al
PCC
Case Report
Panic Attacks in COVID-19
November 21, 2024
This case describes panic attacks that occurred repeatedly as part of the constellation of presenting symptomatology during 2 separate COVID-19 infections.
Tej Joshi, Rita Suri
PCC
Case Report
Eating Disorders and Alcohol Misuse
November 14, 2024
This report highlights associations between anorexia nervosa and alcohol use disorder, emphasizing biological and psychological aspects of both conditions.
Kevin Chen, Patrick Ho, Eduardo Andres Calagua-Bedoya
Letter to the Editor
PCC
Letter to the Editor
Notice of Retraction: Gawash A, et al. Association of Body Dysmorphic–Induced Anabolic-Androgenic Steroid Use With Mental Health Outcomes: A Systematic Review. Prim Care Companion CNS Disord. 2023;25(5):23r03532.
December 10, 2024
Ahmed Gawash, Hasan Zia, Usmaan Al-Shehab, et al
PCC
Letter to the Editor
Is Bariatric Surgery an Antidepressant?
October 29, 2024
The effect of bariatric surgery on mood disorders is uncertain. Read on to find out more.
Ahmed Naguy
PCC
Letter to the Editor
Harm Reduction in Adolescent Inhalant Use
October 15, 2024
The authors discuss harm reduction efforts targeting inhalant use in the adolescent population.
Vania Modesto-Lowe, Roseane Rodrigues, Deanna Sgambato
PCC
Letter to the Editor
Empathy in AI: Insights from Psychodermatology
October 10, 2024
The authors assessed which AI modality has the most potential to help a patient with delusional parasitosis based on the Empathy Scale for Human–Computer Communication score.
Kripa Ahuja, Peter Lio
PCC
Letter to the Editor
Smartphone Applications: Therapy at Your Fingertips
August 20, 2024
Dr Modesto-Lowe and colleagues discuss the advancements in smartphone applications for psychiatry, as well as some of the risks.
Vania Modesto-Lowe, Sofia Adams, Amanda Rossi
PCC
Letter to the Editor
Zeroing in on Xylazine
August 15, 2024
Dr Kaur and colleagues discuss the need to raise awareness among US public and health care professionals about xylazine due to its infiltration into the illicit drug supply.
Jasleen Kaur, Megan Nosol, Vania Modesto-Lowe
More Articles from The Primary Care Companion for DNS Disorders
PCC
Case Series
Alzheimer’s Dementia Confirmed by FDG-PET After Negative Neuropsychological Tests
December 17, 2024
This case series presents several patients who underwent formal neuropsychological testing that did not diagnose dementia, but whose clinical course and neuroimaging findings were consistent with the diagnosis.
Richard Wu, Anshumaan Maharaj, Anne E. Johnson, et al
PCC
Case Series
Cyproheptadine and Dexamethasone Dependence
December 10, 2024
Three cases of cyproheptadine and dexamethasone dependence are presented, with individuals misusing the drugs for rapid weight and muscle gain.
Aniket Mukherjee, Riyal Das, Mayank Kumar, et al
PCC
Case Report
Cisplatin-Etoposide–Induced Hyperammonemic Encephalopathy
November 12, 2024
A 68-year-old cancer patient experienced delirium during the third cycle of treatment with cisplatin-etoposide.
Tanvi Mittal, Arundhathi Krishna Komathodi, Nishanth Jalaja Haridas
PCC
Case Report
Ototoxicity Associated With Mirtazapine
November 7, 2024
A 57-year-old woman experienced hearing loss, tinnitus, and musical hallucinations following several months of mirtazapine use.
Vincent Zhang, Douglas J. Opler
PCC
Case Report
Misdiagnosis of Uremia-Induced Unilateral Visual Hallucination
November 5, 2024
A male patient in his late 40s with type 1 diabetes and chronic stage 3 kidney disease presented with suicidal ideation and persistent unilateral visual hallucinations in his right…
Theodore Huo, Kassidy Kanja, Miki Kiyokawa
PCC
Case Report
Complex Diagnosis of Psychogenic Nonepileptic Seizures
October 31, 2024
Diagnosis and treatment of PNES presents a multifaceted challenge. An interdisciplinary approach involving neurology and psychiatry allows for a comprehensive evaluation and tailored therapeutic interventions.
Sai Niharika Tammineedi, Sindhu Mukesh, Emad Singer, et al
PCC
Correction
Correction: Error in Author Degree
October 31, 2024
PCC
Case Report
Autoimmune Thyroid Disease–Induced Catatonia With Normal Thyroid Function
October 17, 2024
A 26-year-old woman with catatonia and worsening anxiety, insomnia, and alterations in cognition was found to concurrently have autoimmune thyroid disease, but due to an unremarkable initial workup, accurate…
Savana V. Nawojski, Marcus L. Judah, Grace L. Kelly, et al
PCC
Case Report
Self-Harm Obsessions in OCD With Pica
October 10, 2024
A 34-year-old woman presented with self-harm obsessions and compulsions with pica-like behavior in the background of iron deficiency anemia.
Tanvi Mittal, Nishanth Jalaja Haridas
PCC
Brief Report
ED Visit Trends in Children and Youth With Autism
October 8, 2024
Approximately 38.7% of children and youth presented to the emergency department with a concurrent psychiatric diagnosis, highlighting the importance of a holistic psychiatric care approach, irrespective of the primary…
Abid Rizvi, Karrar Husain, Sahar Ashraf, et al
PCC
Case Report
Black Hairy Tongue: A Rare Adverse Effect of Olanzapine
October 3, 2024
A young woman recently diagnosed with a manic episode developed black discoloration on the dorsum of her tongue 3 weeks after starting olanzapine.
Preeti Dalal, Tanisha Pruthi, Manish R. Thakur, et al
PCC
Case Report
Age-Friendly Health Systems
October 3, 2024
The age-friendly health systems movement promotes 4 evidence-based geriatric care principles known as the “4Ms”: What Matters, Medications, Mobility, and Mentation. Read on to find out more.
Carter H. Davis, Christine E. Gould, Susan K. Schultz
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