Pseudomonas aeruginosa severe skin infection in a toddler with X-linked agammaglobulinemia due to a novel BTK mutation. | Read by QxMD (original) (raw)
Case Reports
Journal Article
Niccoló Riccardi, Gioacchino Andrea Rotulo, Federica Favilli, Anna Loy, Daniele Moratto, Silvia Giliani, Alessio Mesini, Maria Victoria Romanini, Stefano Volpi, Andrea Moscatelli, Elio Castagnola
Agammaglobulinemia is a congenital deficit of humoral immunity characterized by a decreased level or complete absence of immunoglobulins and profound reduction of B-lymphocytes associated with an increased risk of life-threatening bacterial infection. We report a case of invasive Pseudomonas aeruginosa severe skin and soft tissue infection treated with vacuum-assisted closure and antibiotics in a toddler with a previously unreported mutation of the Bruton tyrosin kinase gene.
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