WormWiring (original) (raw)

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A website hosting nematode connectomics data and tools for its visualization and analysis

Caenorhabditis elegans

• Adult hermaphrodite, Data of White et al., 1986,The Structure of the Nervous System of the Nematode Caenorhabditis elegans (The Mind of a Worm) Phil. Trans. R. Soc. Lond. B, 314, 1-340.
  Available through WormAtlas.org:https://wormatlas.org/MoW_built0.92/MoW.html
  Skeleton and some volumetric maps of all neuron classes and most individual neurons; Connections of ventral neuron motor neurons by class; Drawings of cell body positions and neuron tracts; Chemical and gap junction synapses; Number of synapses given by class.
• Adult hermaphrodite, Data of Chen, Hall, and Chklovskii, 2006,Wiring optimization can relate neuronal structure and function, PNAS 103: 4723-4728 (doi:10.1073/pnas.0506806103) and_Varshney, Chen, Paniaqua, Hall and Chklovskii, 2011, Structural properties of the C. elegans neuronal network, PLoS Comput. Biol. 3:7:e1001066 (doi:10.1371/journal.pcbi.1001066)._
  Data of White et al., 1986, with additional connectivity in the ventral cord from reannotation of original electron micrographs.
  Connectivity table available through WormAtlas.org: Connectivity Data-download [.xls]
  Number of chemical and gap junction (electrical) synapses for all neurons and motor neurons. Number of NMJ’s for all ventral cord motor neurons.
• Adult hermaphrodite and adult male Data of Cook et al., 2019, Jarrell et al., 2012, and updates. Emmons laboratory data.
  Complete chemical and gap junction connectivity between all neurons, between neurons and end organs (muscles, gonad, gut, hypodermis), and gap junctions between the muscle cells. Connection weights from number of synapses and synapse sizes. Skeleton diagrams and synapse lists for all neurons and muscles directly reconstructed from electron micrographs. Monadic or polyadic structure of each synapse is given. From a reanalysis of the electron micrographs of White et al., 1986 (adult hermaphrodite), Sulston et al., 1980 (male tail), and new electron micrographs, Cook et al., 2019 (male head). WormWiring v1.1 release April 18, 2020
• Witvliet et al Witvliet et al

Pristionchus pacificus

• Adult hermaphrodite pharynx, Data of Bumbarger and Sommer, 2013,System-wide rewiring underlies behavioral differences in predatory and bacterial-feeding nematodes, Cell 152, 109–119. DOI:https://doi.org/10.1016/j.cell.2012.12.013
  • Synapse Connectivity [.xlsx]
  • Consensus Network [.xlsx]
• Adult hermaphrodite chemosensory (amphidial) nervous system. Data of Hong et al., 2019,Evolution of neuronal anatomy and circuitry in two highly divergent nematode species, eLife 2019;8:e47155. DOI: https://doi.org/10.7554/eLife.47155
  • Connectivity table