Priya Shah | XLRI JAMSHEDPUR (original) (raw)
Papers by Priya Shah
Evidence-based Child Health: A Cochrane Review Journal, 2008
This is a summary of a Cochrane review, published in this issue of EBCH, first published as: Shah... more This is a summary of a Cochrane review, published in this issue of EBCH, first published as: Shah PS, Shah VS. Continuous heparin infusion to prevent thrombosis and catheter occlusion in neonates with peripherally placed percutaneous central venous catheters. Cochrane Database of Systematic Reviews 2008, Issue 2. Art. No.: CD002772. DOI: 10.1002/14651858.CD002772.pub3.Further information for this Cochrane review is available in this issue of EBCH in the accompanying Commentary and Characteristics and Key Findings Tables. Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Head & Neck Oncology, 2010
British Journal of Oral & Maxillofacial Surgery, 2009
Lasers in Surgery and Medicine, 2009
IntroductionInterstitial photodynamic therapy remains an attractive remedial option in minimally ... more IntroductionInterstitial photodynamic therapy remains an attractive remedial option in minimally invasive surgery. Our aim in this prospective study was to evaluate the outcome following ultrasound-guided iPDT of deep-seated pathologies. Patients' reports on quality of life with clinical and radiological evaluation were the main end point parameters used to assess the outcome.Interstitial photodynamic therapy remains an attractive remedial option in minimally invasive surgery. Our aim in this prospective study was to evaluate the outcome following ultrasound-guided iPDT of deep-seated pathologies. Patients' reports on quality of life with clinical and radiological evaluation were the main end point parameters used to assess the outcome.Materials and MethodsSixty-eight patients were referred to the UCLH Head and Neck Centre for treatment of various deep-seated pathologies involving the head and neck region, upper and lower limbs. All patients underwent interstitial photodynamic therapy under general anaesthesia, using 0.15 mg/kg mTHPC as the photosensitising agent. Following treatment, patients were followed-up for a mean of 7 months.Sixty-eight patients were referred to the UCLH Head and Neck Centre for treatment of various deep-seated pathologies involving the head and neck region, upper and lower limbs. All patients underwent interstitial photodynamic therapy under general anaesthesia, using 0.15 mg/kg mTHPC as the photosensitising agent. Following treatment, patients were followed-up for a mean of 7 months.ResultsAll three patients who presented with visual problems reported improvement after treatment. Also, 14/17 patients reported improvement of breathing. Improvement of swallowing was reported by 25/30 patients; while speaking improvement was evident in 16/22 patients and 33/40 reported reduction in the disfigurement caused by their pathology. All five patients with impeded limb function reported some degree of improvement. Clinical assessment showed that half of the patients had ‘good response’ to the treatment and a third reported ‘moderate response’ with two patients being free of disease. Radiological assessment comparing imaging 6-week post-PDT to the baseline showed stable pathology with no change in size in 13 patients, minimal response in 18 patients, moderate response in 23 patients and significant response in 11 patients.All three patients who presented with visual problems reported improvement after treatment. Also, 14/17 patients reported improvement of breathing. Improvement of swallowing was reported by 25/30 patients; while speaking improvement was evident in 16/22 patients and 33/40 reported reduction in the disfigurement caused by their pathology. All five patients with impeded limb function reported some degree of improvement. Clinical assessment showed that half of the patients had ‘good response’ to the treatment and a third reported ‘moderate response’ with two patients being free of disease. Radiological assessment comparing imaging 6-week post-PDT to the baseline showed stable pathology with no change in size in 13 patients, minimal response in 18 patients, moderate response in 23 patients and significant response in 11 patients.ConclusionThis study on 68 patients with deep-seated pathologies undergoing interstitial photodynamic therapy provided evidence that PDT can be the fourth modality in the management of tissue disease. Lasers Surg. Med. 41:612–621, 2009. © 2009 Wiley-Liss, Inc.This study on 68 patients with deep-seated pathologies undergoing interstitial photodynamic therapy provided evidence that PDT can be the fourth modality in the management of tissue disease. Lasers Surg. Med. 41:612–621, 2009. © 2009 Wiley-Liss, Inc.
Head & Neck Oncology, 2009
Head & Neck Oncology, 2009
O1 Elastic light scattering spectroscopy for the detection of pre-cancer: an overview Irving J Bi... more O1 Elastic light scattering spectroscopy for the detection of pre-cancer: an overview Irving J Bigio O2 The clinical application of elastic scattering spectroscopy in the head and neck Colin Hopper O3 Fluorescence spectroscopy and fluorescence imaging for tissue diagnostics -principles and methods Herbert Stepp et al O4 Diagnosis of head & neck malignancy using fluorescence spectroscopy and imaging Christian Stephan Betz et al O5 Optical coherence tomography: challenge and opportunity Zhongping Chen O6 The clinical application of optical coherence tomography in the head and neck Brian JF Wong O7 Differential pathlength spectroscopy for diagnosis of head and neck cancer Henricus JCM Sterenborg et al O8 Raman spectroscopy in clinical diagnosis of head & neck pathology Max JH Witjes O9 Role of histopathologic and phenotypic assessment in the development and validation of optical diagnostic devices for head and neck mucosal lesions Adel K El-Naggar O10 Ploidy analysis post Sudbø -where are we now? Marco Novelli O11 Optical technologies for detection and diagnosis of oral neoplasia Ann Gillenwater O12 Spectral scatter scanning system for surgical margin detection Brian W Pogue et al O13 Microimaging FT-IR of Head and Neck Tumours.The case of salivary glands Carla Conti et al O14 Characterization of laryngeal carcinoma by confocal endomicroscopy Muriel Abbaci et al O15 Early experience with in-vivo optical coherence tomography for differentiating lesions of the upper aerodigestive tract Christian Stephan Betz et al O16 Immediate ex-vivo optical coherence tomography of suspicious oral lesions Zaid Hamdoon et al O17 Qualitative diagnostics of oral mucosa by means of multiple fluorophore analysis Miriam Havel et al O18 Fluorescence kinetics of Foscan, Fospeg and Foslip in the window-chamber model Sebastiaan De Visscher et al O19 Interrogation of skin pathology using elastic scattering spectroscopy Yan Jiao et al Poster presentations P1 Optical diagnostic techniques in the head and neck Waseem Jerjes et al P2 Optical coherence tomography in the diagnosis of oral dysplasia Syeda Amna Azim et al P3 Fluorescence spectroscopy in the detection of oral dysplasia Iordanis Toursounidis et al P4 Raman spectroscopy and oral cancer Nasser Alqhtani et al P5 The clinical application of elastic scattering spectroscopy Adel Alenazi et al Open Access CONTENTS
Head & Neck Oncology, 2009
Lasers in Medical Science, 2009
Photodynamic therapy is an emerging technology and results from the interactions between a photos... more Photodynamic therapy is an emerging technology and results from the interactions between a photosensitiser, oxygen and light. The delivery of light may either be by surface illumination or by interstitial application. We describe the first clinical application of ultrasound-guided interstitial photodynamic therapy (US-iPDT). A total of 23 treatments with meta-tetra-hydroxyphenyl chlorine (mTHPC) and ultrasound-guided interstitial photodynamic therapy were performed on 21 patients with various conditions at the Head & Neck Centre, University College London Hospital. The needles could be clearly identified during insertion in all 23 treatments, and it was possible to guide parallel needle insertions using ultrasound. Although the resolution of ultrasound is not as high as that of other imaging modalities [i.e. computed tomography (CT) and magnetic resonance imaging (MRI)] it was satisfactory in identifying the centre and the peripheries of the pathological lesions. Ultrasound is very easy to perform, non-invasive, relatively inexpensive, quick, convenient, non-ionising, suited to the imaging of soft tissues and does not cause any discomfort. Ultrasound can be used to guide ‘real-time’ photodynamic therapy in deep-seated tumours and other malformations and can augment the information from other imaging modalities without affecting the patient’s treatment outcome.
Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, 2010
Objective. Earlier reports, including a preliminary study within our unit, have shown that the su... more Objective. Earlier reports, including a preliminary study within our unit, have shown that the surgeon's experience is one of the most influential factors in determining the likelihood of both permanent inferior alveolar nerve (IAN) and lingual nerve (LN) paresthesia, following third molar surgery. The effect of this and other factors influencing such prevalence are assessed in this study. Study design. This prospective study involved 3236 patients who underwent surgical removal of impacted third molars. Patients' demographics and radiological parameters were recorded along with the grade of the treating surgeon. The prevalence of inferior alveolar and lingual nerves paresthesia at 1 month, 6 months, and 18 to 24 months postoperatively were also traced. Results. At 1 month postoperatively, the incidence of IAN paresthesia was 1.5% and the LN was 1.8%. These figures decreased over time and 18 to 24 months postoperatively, the incidence of permanent dysfunction of the IAN was 0.6% and LN was 1.1%. With regard to inferior alveolar nerve paresthesia, risk factors included the patient's age (26-30 years), horizontally impacted teeth, close radiographic proximity to the inferior alveolar canal (IAC), and treatment by trainee surgeons. With regard to the lingual nerve, risk factors included male patients, distoangular impactions, close radiographic proximity to the IAC, and treatment by trainee surgeons. Conclusion. One of the main risk factors of developing permanent sensory dysfunction in the distribution of these nerves is related to the surgical skills/experience of the operator. Other factors are associated with the type of
Journal of Oral and Maxillofacial Surgery, 2010
Head & Neck Oncology, 2009
British Journal of Oral & Maxillofacial Surgery, 2009
Background: The clearance of surgical margins at the primary site is widely thought to influence ... more Background: The clearance of surgical margins at the primary site is widely thought to influence the subsequent course of the disease in patients operated on for oral and oropharyngeal carcinoma. In some reports the adverse impact of close or involved margins was not negated by postoperative radiotherapy. These findings, in addition to descriptive histopathological studies, have led some authors to recommend margins of more than a macroscopic clearance of 1 cm at certain subsites. We have therefore examined the relation between the condition of surgical margins and local recurrence and disease-specific survival. Methods: Identical treatment protocols were used to treat two independent groups of patients (Sydney, Australia, n = 237; Lanarkshire, n = 95) who presented with previously untreated carcinoma of the mouth or oropharynx. All patients were operated on with the primary objective of achieving a macroscopic clearance of 1 cm. Postoperative radiotherapy was used according to a protocol. Data about patients were entered into comprehensive computerised databases prospectively. Known clinical and pathological prognostic indicators, in addition to the condition of surgical margins, were analysed to find out if they were predictive of local recurrence and disease-specific survival using the Cox proportional hazard model. Results: Local recurrence was predicted by the presence of perineural invasion at the primary site in both groups. Disease-specific survival was predicted by the presence and extent of regional lymph node metastases in both groups. The condition of surgical margins (clear, close, or involved) did not predict local recurrence, or disease-specific survival on multivariate analysis. Conclusions: A macroscopic margin of 1 cm seems adequate in the surgical management of oral and oropharyngeal carcinoma. For most patients who have close or involved margins the biology of the disease influences the subsequent course irrespective of the width of clearance of tumour.
Head & Neck Oncology, 2009
British Journal of Oral & Maxillofacial Surgery, 2009
Medical Image Analysis, Volume 47, Issue 7, Pages e11, October 2009, Authors:WaseemJerjes; Tahwin... more Medical Image Analysis, Volume 47, Issue 7, Pages e11, October 2009, Authors:WaseemJerjes; Tahwinder Upile; Mohammed El-Maaytah; Syedda Abbas; Farai Nhembe; Dipali Gudka; Priya Shah; Shinali Patel; Maria Kalkani; Colin Hopper. ...
British Journal of Oral & Maxillofacial Surgery, 2009
O1 Elastic light scattering spectroscopy for the detection of pre-cancer: an overview Irving J Bi... more O1 Elastic light scattering spectroscopy for the detection of pre-cancer: an overview Irving J Bigio O2 The clinical application of elastic scattering spectroscopy in the head and neck Colin Hopper O3 Fluorescence spectroscopy and fluorescence imaging for tissue diagnostics -principles and methods Herbert Stepp et al O4 Diagnosis of head & neck malignancy using fluorescence spectroscopy and imaging Christian Stephan Betz et al O5 Optical coherence tomography: challenge and opportunity Zhongping Chen O6 The clinical application of optical coherence tomography in the head and neck Brian JF Wong O7 Differential pathlength spectroscopy for diagnosis of head and neck cancer Henricus JCM Sterenborg et al O8 Raman spectroscopy in clinical diagnosis of head & neck pathology Max JH Witjes O9 Role of histopathologic and phenotypic assessment in the development and validation of optical diagnostic devices for head and neck mucosal lesions Adel K El-Naggar O10 Ploidy analysis post Sudbø -where are we now? Marco Novelli O11 Optical technologies for detection and diagnosis of oral neoplasia Ann Gillenwater O12 Spectral scatter scanning system for surgical margin detection Brian W Pogue et al O13 Microimaging FT-IR of Head and Neck Tumours.The case of salivary glands Carla Conti et al O14 Characterization of laryngeal carcinoma by confocal endomicroscopy Muriel Abbaci et al O15 Early experience with in-vivo optical coherence tomography for differentiating lesions of the upper aerodigestive tract Christian Stephan Betz et al O16 Immediate ex-vivo optical coherence tomography of suspicious oral lesions Zaid Hamdoon et al O17 Qualitative diagnostics of oral mucosa by means of multiple fluorophore analysis Miriam Havel et al O18 Fluorescence kinetics of Foscan, Fospeg and Foslip in the window-chamber model Sebastiaan De Visscher et al O19 Interrogation of skin pathology using elastic scattering spectroscopy Yan Jiao et al Poster presentations P1 Optical diagnostic techniques in the head and neck Waseem Jerjes et al P2 Optical coherence tomography in the diagnosis of oral dysplasia Syeda Amna Azim et al P3 Fluorescence spectroscopy in the detection of oral dysplasia Iordanis Toursounidis et al P4 Raman spectroscopy and oral cancer Nasser Alqhtani et al P5 The clinical application of elastic scattering spectroscopy Adel Alenazi et al Open Access CONTENTS
Head & Neck Oncology, 2009
Evidence-based Child Health: A Cochrane Review Journal, 2008
This is a summary of a Cochrane review, published in this issue of EBCH, first published as: Shah... more This is a summary of a Cochrane review, published in this issue of EBCH, first published as: Shah PS, Shah VS. Continuous heparin infusion to prevent thrombosis and catheter occlusion in neonates with peripherally placed percutaneous central venous catheters. Cochrane Database of Systematic Reviews 2008, Issue 2. Art. No.: CD002772. DOI: 10.1002/14651858.CD002772.pub3.Further information for this Cochrane review is available in this issue of EBCH in the accompanying Commentary and Characteristics and Key Findings Tables. Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Head & Neck Oncology, 2010
British Journal of Oral & Maxillofacial Surgery, 2009
Lasers in Surgery and Medicine, 2009
IntroductionInterstitial photodynamic therapy remains an attractive remedial option in minimally ... more IntroductionInterstitial photodynamic therapy remains an attractive remedial option in minimally invasive surgery. Our aim in this prospective study was to evaluate the outcome following ultrasound-guided iPDT of deep-seated pathologies. Patients' reports on quality of life with clinical and radiological evaluation were the main end point parameters used to assess the outcome.Interstitial photodynamic therapy remains an attractive remedial option in minimally invasive surgery. Our aim in this prospective study was to evaluate the outcome following ultrasound-guided iPDT of deep-seated pathologies. Patients' reports on quality of life with clinical and radiological evaluation were the main end point parameters used to assess the outcome.Materials and MethodsSixty-eight patients were referred to the UCLH Head and Neck Centre for treatment of various deep-seated pathologies involving the head and neck region, upper and lower limbs. All patients underwent interstitial photodynamic therapy under general anaesthesia, using 0.15 mg/kg mTHPC as the photosensitising agent. Following treatment, patients were followed-up for a mean of 7 months.Sixty-eight patients were referred to the UCLH Head and Neck Centre for treatment of various deep-seated pathologies involving the head and neck region, upper and lower limbs. All patients underwent interstitial photodynamic therapy under general anaesthesia, using 0.15 mg/kg mTHPC as the photosensitising agent. Following treatment, patients were followed-up for a mean of 7 months.ResultsAll three patients who presented with visual problems reported improvement after treatment. Also, 14/17 patients reported improvement of breathing. Improvement of swallowing was reported by 25/30 patients; while speaking improvement was evident in 16/22 patients and 33/40 reported reduction in the disfigurement caused by their pathology. All five patients with impeded limb function reported some degree of improvement. Clinical assessment showed that half of the patients had ‘good response’ to the treatment and a third reported ‘moderate response’ with two patients being free of disease. Radiological assessment comparing imaging 6-week post-PDT to the baseline showed stable pathology with no change in size in 13 patients, minimal response in 18 patients, moderate response in 23 patients and significant response in 11 patients.All three patients who presented with visual problems reported improvement after treatment. Also, 14/17 patients reported improvement of breathing. Improvement of swallowing was reported by 25/30 patients; while speaking improvement was evident in 16/22 patients and 33/40 reported reduction in the disfigurement caused by their pathology. All five patients with impeded limb function reported some degree of improvement. Clinical assessment showed that half of the patients had ‘good response’ to the treatment and a third reported ‘moderate response’ with two patients being free of disease. Radiological assessment comparing imaging 6-week post-PDT to the baseline showed stable pathology with no change in size in 13 patients, minimal response in 18 patients, moderate response in 23 patients and significant response in 11 patients.ConclusionThis study on 68 patients with deep-seated pathologies undergoing interstitial photodynamic therapy provided evidence that PDT can be the fourth modality in the management of tissue disease. Lasers Surg. Med. 41:612–621, 2009. © 2009 Wiley-Liss, Inc.This study on 68 patients with deep-seated pathologies undergoing interstitial photodynamic therapy provided evidence that PDT can be the fourth modality in the management of tissue disease. Lasers Surg. Med. 41:612–621, 2009. © 2009 Wiley-Liss, Inc.
Head & Neck Oncology, 2009
Head & Neck Oncology, 2009
O1 Elastic light scattering spectroscopy for the detection of pre-cancer: an overview Irving J Bi... more O1 Elastic light scattering spectroscopy for the detection of pre-cancer: an overview Irving J Bigio O2 The clinical application of elastic scattering spectroscopy in the head and neck Colin Hopper O3 Fluorescence spectroscopy and fluorescence imaging for tissue diagnostics -principles and methods Herbert Stepp et al O4 Diagnosis of head & neck malignancy using fluorescence spectroscopy and imaging Christian Stephan Betz et al O5 Optical coherence tomography: challenge and opportunity Zhongping Chen O6 The clinical application of optical coherence tomography in the head and neck Brian JF Wong O7 Differential pathlength spectroscopy for diagnosis of head and neck cancer Henricus JCM Sterenborg et al O8 Raman spectroscopy in clinical diagnosis of head & neck pathology Max JH Witjes O9 Role of histopathologic and phenotypic assessment in the development and validation of optical diagnostic devices for head and neck mucosal lesions Adel K El-Naggar O10 Ploidy analysis post Sudbø -where are we now? Marco Novelli O11 Optical technologies for detection and diagnosis of oral neoplasia Ann Gillenwater O12 Spectral scatter scanning system for surgical margin detection Brian W Pogue et al O13 Microimaging FT-IR of Head and Neck Tumours.The case of salivary glands Carla Conti et al O14 Characterization of laryngeal carcinoma by confocal endomicroscopy Muriel Abbaci et al O15 Early experience with in-vivo optical coherence tomography for differentiating lesions of the upper aerodigestive tract Christian Stephan Betz et al O16 Immediate ex-vivo optical coherence tomography of suspicious oral lesions Zaid Hamdoon et al O17 Qualitative diagnostics of oral mucosa by means of multiple fluorophore analysis Miriam Havel et al O18 Fluorescence kinetics of Foscan, Fospeg and Foslip in the window-chamber model Sebastiaan De Visscher et al O19 Interrogation of skin pathology using elastic scattering spectroscopy Yan Jiao et al Poster presentations P1 Optical diagnostic techniques in the head and neck Waseem Jerjes et al P2 Optical coherence tomography in the diagnosis of oral dysplasia Syeda Amna Azim et al P3 Fluorescence spectroscopy in the detection of oral dysplasia Iordanis Toursounidis et al P4 Raman spectroscopy and oral cancer Nasser Alqhtani et al P5 The clinical application of elastic scattering spectroscopy Adel Alenazi et al Open Access CONTENTS
Head & Neck Oncology, 2009
Lasers in Medical Science, 2009
Photodynamic therapy is an emerging technology and results from the interactions between a photos... more Photodynamic therapy is an emerging technology and results from the interactions between a photosensitiser, oxygen and light. The delivery of light may either be by surface illumination or by interstitial application. We describe the first clinical application of ultrasound-guided interstitial photodynamic therapy (US-iPDT). A total of 23 treatments with meta-tetra-hydroxyphenyl chlorine (mTHPC) and ultrasound-guided interstitial photodynamic therapy were performed on 21 patients with various conditions at the Head & Neck Centre, University College London Hospital. The needles could be clearly identified during insertion in all 23 treatments, and it was possible to guide parallel needle insertions using ultrasound. Although the resolution of ultrasound is not as high as that of other imaging modalities [i.e. computed tomography (CT) and magnetic resonance imaging (MRI)] it was satisfactory in identifying the centre and the peripheries of the pathological lesions. Ultrasound is very easy to perform, non-invasive, relatively inexpensive, quick, convenient, non-ionising, suited to the imaging of soft tissues and does not cause any discomfort. Ultrasound can be used to guide ‘real-time’ photodynamic therapy in deep-seated tumours and other malformations and can augment the information from other imaging modalities without affecting the patient’s treatment outcome.
Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, 2010
Objective. Earlier reports, including a preliminary study within our unit, have shown that the su... more Objective. Earlier reports, including a preliminary study within our unit, have shown that the surgeon's experience is one of the most influential factors in determining the likelihood of both permanent inferior alveolar nerve (IAN) and lingual nerve (LN) paresthesia, following third molar surgery. The effect of this and other factors influencing such prevalence are assessed in this study. Study design. This prospective study involved 3236 patients who underwent surgical removal of impacted third molars. Patients' demographics and radiological parameters were recorded along with the grade of the treating surgeon. The prevalence of inferior alveolar and lingual nerves paresthesia at 1 month, 6 months, and 18 to 24 months postoperatively were also traced. Results. At 1 month postoperatively, the incidence of IAN paresthesia was 1.5% and the LN was 1.8%. These figures decreased over time and 18 to 24 months postoperatively, the incidence of permanent dysfunction of the IAN was 0.6% and LN was 1.1%. With regard to inferior alveolar nerve paresthesia, risk factors included the patient's age (26-30 years), horizontally impacted teeth, close radiographic proximity to the inferior alveolar canal (IAC), and treatment by trainee surgeons. With regard to the lingual nerve, risk factors included male patients, distoangular impactions, close radiographic proximity to the IAC, and treatment by trainee surgeons. Conclusion. One of the main risk factors of developing permanent sensory dysfunction in the distribution of these nerves is related to the surgical skills/experience of the operator. Other factors are associated with the type of
Journal of Oral and Maxillofacial Surgery, 2010
Head & Neck Oncology, 2009
British Journal of Oral & Maxillofacial Surgery, 2009
Background: The clearance of surgical margins at the primary site is widely thought to influence ... more Background: The clearance of surgical margins at the primary site is widely thought to influence the subsequent course of the disease in patients operated on for oral and oropharyngeal carcinoma. In some reports the adverse impact of close or involved margins was not negated by postoperative radiotherapy. These findings, in addition to descriptive histopathological studies, have led some authors to recommend margins of more than a macroscopic clearance of 1 cm at certain subsites. We have therefore examined the relation between the condition of surgical margins and local recurrence and disease-specific survival. Methods: Identical treatment protocols were used to treat two independent groups of patients (Sydney, Australia, n = 237; Lanarkshire, n = 95) who presented with previously untreated carcinoma of the mouth or oropharynx. All patients were operated on with the primary objective of achieving a macroscopic clearance of 1 cm. Postoperative radiotherapy was used according to a protocol. Data about patients were entered into comprehensive computerised databases prospectively. Known clinical and pathological prognostic indicators, in addition to the condition of surgical margins, were analysed to find out if they were predictive of local recurrence and disease-specific survival using the Cox proportional hazard model. Results: Local recurrence was predicted by the presence of perineural invasion at the primary site in both groups. Disease-specific survival was predicted by the presence and extent of regional lymph node metastases in both groups. The condition of surgical margins (clear, close, or involved) did not predict local recurrence, or disease-specific survival on multivariate analysis. Conclusions: A macroscopic margin of 1 cm seems adequate in the surgical management of oral and oropharyngeal carcinoma. For most patients who have close or involved margins the biology of the disease influences the subsequent course irrespective of the width of clearance of tumour.
Head & Neck Oncology, 2009
British Journal of Oral & Maxillofacial Surgery, 2009
Medical Image Analysis, Volume 47, Issue 7, Pages e11, October 2009, Authors:WaseemJerjes; Tahwin... more Medical Image Analysis, Volume 47, Issue 7, Pages e11, October 2009, Authors:WaseemJerjes; Tahwinder Upile; Mohammed El-Maaytah; Syedda Abbas; Farai Nhembe; Dipali Gudka; Priya Shah; Shinali Patel; Maria Kalkani; Colin Hopper. ...
British Journal of Oral & Maxillofacial Surgery, 2009
O1 Elastic light scattering spectroscopy for the detection of pre-cancer: an overview Irving J Bi... more O1 Elastic light scattering spectroscopy for the detection of pre-cancer: an overview Irving J Bigio O2 The clinical application of elastic scattering spectroscopy in the head and neck Colin Hopper O3 Fluorescence spectroscopy and fluorescence imaging for tissue diagnostics -principles and methods Herbert Stepp et al O4 Diagnosis of head & neck malignancy using fluorescence spectroscopy and imaging Christian Stephan Betz et al O5 Optical coherence tomography: challenge and opportunity Zhongping Chen O6 The clinical application of optical coherence tomography in the head and neck Brian JF Wong O7 Differential pathlength spectroscopy for diagnosis of head and neck cancer Henricus JCM Sterenborg et al O8 Raman spectroscopy in clinical diagnosis of head & neck pathology Max JH Witjes O9 Role of histopathologic and phenotypic assessment in the development and validation of optical diagnostic devices for head and neck mucosal lesions Adel K El-Naggar O10 Ploidy analysis post Sudbø -where are we now? Marco Novelli O11 Optical technologies for detection and diagnosis of oral neoplasia Ann Gillenwater O12 Spectral scatter scanning system for surgical margin detection Brian W Pogue et al O13 Microimaging FT-IR of Head and Neck Tumours.The case of salivary glands Carla Conti et al O14 Characterization of laryngeal carcinoma by confocal endomicroscopy Muriel Abbaci et al O15 Early experience with in-vivo optical coherence tomography for differentiating lesions of the upper aerodigestive tract Christian Stephan Betz et al O16 Immediate ex-vivo optical coherence tomography of suspicious oral lesions Zaid Hamdoon et al O17 Qualitative diagnostics of oral mucosa by means of multiple fluorophore analysis Miriam Havel et al O18 Fluorescence kinetics of Foscan, Fospeg and Foslip in the window-chamber model Sebastiaan De Visscher et al O19 Interrogation of skin pathology using elastic scattering spectroscopy Yan Jiao et al Poster presentations P1 Optical diagnostic techniques in the head and neck Waseem Jerjes et al P2 Optical coherence tomography in the diagnosis of oral dysplasia Syeda Amna Azim et al P3 Fluorescence spectroscopy in the detection of oral dysplasia Iordanis Toursounidis et al P4 Raman spectroscopy and oral cancer Nasser Alqhtani et al P5 The clinical application of elastic scattering spectroscopy Adel Alenazi et al Open Access CONTENTS
Head & Neck Oncology, 2009