Neslihan Taşdelen | Yeditepe University (original) (raw)

Papers by Neslihan Taşdelen

ÖZET Penil metastaz nadir görülen bir durumdur. Genelde orijin genitoüriner malignitelerdir. Many... more ÖZET Penil metastaz nadir görülen bir durumdur. Genelde orijin genitoüriner malignitelerdir. Manyetik rezonans görüntüleme (MRG) preoperatif görüntülemede kullanılabilecek bir tanı metodudur. Son dönemde tümöral görüntülemede ileri MRG tekniklerinden olan difüzyon ağırlıklı görüntüleme (DAG) kullanılmaktadır. Bu olgu sunumunda nadir görülen bir durum olan mesane kanseri penil metastazı radyolojik bulgularını özellikle tanıda yardımcı olduğunu düşündüğümüz DAG bulgularıyla ilgili literatür eşliğinde sunmayı amaçladık. Anahtar kelimeler: Diffüzyon ağırlıklı görüntüleme, Penil neoplaziler, Mesane neoplazileri, Manyetik rezonans görüntüleme ABSTRACT Penile metastasis is a very rare entity that mostly the origin of the tumor is the genitourinary malignancies. Magnetic resonance imaging (MRI) is the method of choice in the preoperative diagnosis. Recently, diffusion weighted imaging (DWI) is used in tumor imaging which is an advanced technique of MRI. We report a case of bladder carcinoma...

Penil metastaz nadir gorulen bir durumdur. Genelde orijin genitouriner malignitelerdir. Manyetik ... more Penil metastaz nadir gorulen bir durumdur. Genelde orijin genitouriner malignitelerdir. Manyetik rezonans goruntuleme (MRG) preoperatif goruntulemede kullanilabilecek bir tani metodudur. Son donemde tumoral goruntulemede ileri MRG tekniklerinden olan difuzyon agirlikli goruntuleme (DAG) kullanilmaktadir. Bu olgu sunumunda nadir gorulen bir durum olan mesane kanseri penil metastazi radyolojik bulgularini ozellikle tanida yardimci oldugunu dusundugumuz DAG bulgulariyla ilgili literatur esliginde sunmayi amacladik

Acta Radiologica, 2016

Background Chondromalacia patellae is a very common disorder. Although magnetic resonance imaging... more Background Chondromalacia patellae is a very common disorder. Although magnetic resonance imaging (MRI) is widely used to investigate patellar cartilage lesions, there is no descriptive MRI-based grading system for chondromalacia patellae. Purpose To propose a new MRI grading system for chondromalacia patellae with corresponding high resolution images which might be useful in precisely reporting and comparing knee examinations in routine daily practice and used in predicting natural course and clinical outcome of the patellar cartilage lesions. Material and Methods High resolution fat-saturated proton density (FS PD) images in the axial plane with corresponding T2 mapping images were reviewed. A detailed MRI grading system covering the deficiencies of the existing gradings has been set and presented on these images. Two experienced observers blinded to clinical data examined 44 knee MR images and evaluated patellar cartilage changes according to the proposed grading system. Inter- a...

Balkan Medical Journal, 2016

Background: Diffusion and diffusion tensor imaging techniques (DTI) are widely available and used... more Background: Diffusion and diffusion tensor imaging techniques (DTI) are widely available and used both in central nervous system and body imaging, including gynecological diseases. Aims: The aims of this study were to assess the capability of DTI of uterine zones in relation to the menstrual cycle and ascertain the normal apparent diffusion coefficient and fractional anisotropy values at 3T magnetic resonance imaging (MRI). Study Design: Prospective clinical study. Methods: A total of 13 young reproductive and 12 postmenopausal healthy volunteers were included in the study. MRI examination included sagittal T2-weighted and singleshot echo planar imaging DTI obtained under free breathing. Fractional anisotropy (FA) values of the endometrium, junctional zone, and myometrium were determined. Results: The median (minimum-maximum) FA of the endometrium, myometrium, and junctional zone of the reproductive group were 0.31 (0.260-0.465), 0.42 (0.302-0.664), and 0.58 (0.420-0.745), respectively, in the proliferative phase and 0.26 (0.180-0.413), 0.48 (0.357-0.656), and 0.59 (0.490-0.675)], respectively, in the secretory phase. In the postmenopausal group, the FA values of the endometrium, myometrium, and junctional zone were 0.275 (0.136-0.425), 0.255 (0.191-0.553), and 0.27 (0.129-0.397), respectively. Apparent diffusion coefficient (ADC) values of the endometrium, myometrium, and junctional zone of the reproductive group were 1.25±0.254 (0.970-1.463), 1.67 (1.213-1.854), and 1.23 (0.853-1.301), respectively, in the proliferative phase and 1.32±0.283 (1.165-1.706), 1.55 (1.360-1.791), and 1.17 (1.163-1.705), respectively, in the secretory phase. In the postmenopausal group, the ADC values of the endometrium, myometrium, and junctional zone were measured as 1.100±0.192 (0.850-1.302), 1.14 (0.864-1.283), and 1.09 (0.912-1.291). The FA values of the endometrium and myometrium were lower in the secretory phase of the reproductive group, while ADC values were higher. However, both the FA and ADC values were lower in the postmenopausal group. Conclusion: The present study showed that uterine DTI is feasible when used quantitatively. While FA values tend to decrease, ADC values increase significantly in all zones in the secretory phase except the junctional zone. Zonal FA and ADC values of postmenopausal women are lower in comparison to those in young women.

Cerrahpasa Tıp Dergisi, 2008

Tek tarafl› spondilolizis varl›¤›nda karfl› pedikülde skleroz geliflimi nisbeten nadir olarak gör... more Tek tarafl› spondilolizis varl›¤›nda karfl› pedikülde skleroz geliflimi nisbeten nadir olarak görülebilen bir durumdur. Tan›mlanan görünüm ba-z› durumlarda tan› güçlü¤üne yol açabilmekte ve gereksiz cerrahilere zemin haz›rlayabilmektedir. Bu sunumdaki amac›m›z olgular eflli¤inde konuyu sunmak ve literatür eflli¤inde tart›flmakt›r.

Türkiye Fiziksel Tip ve Rehabilitasyon Dergisi, 2015

Endometriosis is a common disease characterized by the presence of endometrial tissue outside the... more Endometriosis is a common disease characterized by the presence of endometrial tissue outside the uterus, such as over, colon, nasal mucosa. Furthermore, it can affect sciatic nerve as a rare presentation causing cyclic sciatica, chronic pelvic pain, paresis, and paresthesia. Early diagnosis and treatment is very important to minimize the nerve damage caused by endometrial focus on sciatic nerve. Diagnosis of sciatica due to endometriosis can be made by magnetic resonance neurography (MRN), thereby identifying abnormalities of the sciatic nerve in patients with unexplained sciatica. MRN is a sensitive tool for evaluating both the lumbosacral plexus and sciatic nerve. We described a 38-year-old female patient with cyclic sciatica for 4 years. She had an endometrial focus compressing sciatic nerve at left sciatic foramen level that was diagnosed by MRN. In this case report, we aimed to underline the importance of appropriate diagnostic tools in the patients with extraspinal sciatica.

Balkan Medical Journal, 2016

Cerrahpasa Tıp Dergisi, 2008

Türkiye Fiziksel Tip ve Rehabilitasyon Dergisi, 2015

Diagnostic and interventional radiology (Ankara, Turkey), 2009

The purpose of this study was to evaluate the feasibility of diffusion-weighted imaging in the di... more The purpose of this study was to evaluate the feasibility of diffusion-weighted imaging in the diagnosis of the urinary bladder and prostate carcinomas. The apparent diffusion coefficient (ADC) values of the malignant and normal tissues were correlated. A total of 23 patients with 14 urinary bladder carcinomas and 9 prostate carcinomas, and 50 healthy controls with normal ultrasonographic urinary bladder and prostate gland imaging findings were enrolled in the study. The ADC values were reported as the mean +/- standard deviation. Student's t test was performed to compare the ADC values of the normal and pathological tissues. Diffusion-weighted imaging (DWI) was performed with b factors of 0, 500, and 1000 s/mm(2), and the ADC values of the normal tissues and lesions were calculated. The mean ADC value of the urinary bladder wall of the control group and bladder carcinomas were (2.08 +/- 0.22 x 10(-3)mm(2)/s) and (0.94 +/- 0.18 x 10(-3)mm(2)/s), respectively. In addition, the AD...

Diagnostic and Interventional Radiology, 2010

Diagnostic and Interventional Radiology, 2011

C arpal tunnel syndrome (CTS) is the most common peripheral neuropathy of an upper extremity, and... more C arpal tunnel syndrome (CTS) is the most common peripheral neuropathy of an upper extremity, and it is caused by an entrapment of the median nerve at the level of the carpal tunnel (1). The carpal tunnel is formed by the carpal bones, which form a concave arch, and the transverse carpal ligament, which lies on the arch. The ligament is also fused to the pisiform, the hook of the hamate at the ulnar side, the tubercle of the navicular bone, the crest of the trapezium, and the radial styloid (2). CTS is a common disorder with an estimated 8% annual incidence rate, and an accurate diagnosis can be achieved by considering the patient's electrodiagnostic features and symptom characteristics. Electrodiagnostic testing is considered the single most accurate method of diagnosis, but a high rate of false negatives and positives are also well documented. If electrodiagnostic findings are not available, then the patient's characteristic symptoms and physical examination may provide the best diagnostic information (3). Fat-saturated, T2-weighted magnetic resonance imaging (MRI) can reveal morphological changes in CTS patients, such as nerve enlargement, nerve flattening, increased nerve signal intensity, and bowing of the flexor retinaculum at the level of the hamate hook. However, the sensitivity and specificity of MRI findings are low; therefore, conventional MRI may provide insufficient diagnostic data for clinically assessing CTS (1). Diffusion tensor imaging (DTI) is an advanced MRI technique that is used to measure the diffusion of water in tissue (4). In white matter, water diffusion is anisotropic due to its impermeable boundaries, and this anisotropy can be measured with DTI; therefore, its main clinical application is white-matter tract visualization, but recently, it has been shown that DTI can be useful for imaging non-neural tissue, such as peripheral nerves (5-8), muscle (9), and prostate (10). There are a few preliminary reports in the literature on the application of DTI for diagnosis of CTS, but they include a limited number of subjects. Nevertheless, these reports found decreased fractional anisotropy (FA) and increased radial diffusivity at the median nerve within the carpal tunnel (8, 11, 12). Here, we investigated DTI's diagnostic utility in a large group of CTS patients using two quantitative measures: FA and the apparent diffusion coefficient (ADC). We also measured the correlation between CTS severity and FA. Materials and methods Patients We prospectively evaluated 57 wrists in 38 CTS patients (34 females and 4 males; mean age, 48 years; age range, 25-73 years; median age, MUSCULOSKELETAL IMAGING

Acta Radiologica, 2009

Background: Magnetic resonance (MR) imaging has been established as the best imaging modality for... more Background: Magnetic resonance (MR) imaging has been established as the best imaging modality for the detection, localization, and staging of uterine cancers. Recently, the usefulness of diffusion-weighted imaging (DWI) in the diagnosis of cancers has been reported in several studies. Purpose: To calculate the apparent diffusion coefficient (ADC) values of normal uterine zones as well as benign and malignant uterine diseases, and to determine a cut-off ADC value for the quantitative detection of uterine malignancies with DWI. Material and Methods: Eighty-seven patients (mean age 53 years) with 107 benign and malignant uterine pathologies and 50 healthy controls (mean age 38 years) were enrolled in the study. DWI was performed with b factors of 0, 500, and 1000 s/mm2. Results: The ADC values of benign and malignant lesions were compared using Student's t test. The mean and the standard deviation of the ADC values of the control group were as follows: myometrium 1.76±0.19×10−3 mm2...

European Journal of Radiology Extra, 2009

Acta Radiologica, 2016

Balkan Medical Journal, 2016

Cerrahpasa Tıp Dergisi, 2008

Türkiye Fiziksel Tip ve Rehabilitasyon Dergisi, 2015

Balkan Medical Journal, 2016

Cerrahpasa Tıp Dergisi, 2008

Türkiye Fiziksel Tip ve Rehabilitasyon Dergisi, 2015

Diagnostic and interventional radiology (Ankara, Turkey), 2009

Diagnostic and Interventional Radiology, 2010

Diagnostic and Interventional Radiology, 2011

Acta Radiologica, 2009

European Journal of Radiology Extra, 2009