Deepak Langade | Dr.D. Y. Patil University Navi Mumbai (original) (raw)
Papers by Deepak Langade
Journal of Yoga and Physiotherapy
Journal of Obstetrics and Gynaecology Research
The Physician
Poster presented at Forum for Interdisciplinary Research in Medicine, Science & Technology Confer... more Poster presented at Forum for Interdisciplinary Research in Medicine, Science & Technology Conference, Moscow 2020 Peer reviewed by JS Bamrah, Ananthakrishnan Raghuraman, Soumit Dasgupta & Jyothi Srinivasan
Cureus
Background Stress, anxiety and impeded sleep are a frequent feature of life in modern societies. ... more Background Stress, anxiety and impeded sleep are a frequent feature of life in modern societies. Across socioeconomic strata, stress, anxiety and ineffective sleep detract from healthful living and serve as precursors of various ailments. The use of herbs to offset these antecedents and outcomes has greatly increased in recent years. Ashwagandha, an adaptogenic Ayurvedic herb, has been often used to combat and reduce stress and thereby enhance general wellbeing. While there have been other studies documenting the use of Ashwagandha for stress resistance, this is the first study to use a high-concentration root extract while also varying the dosage substantially. Therefore, this is the first study to offer insight into dose-response of a high concentration root extract.
Advances in Therapy
The authors have noticed an error and omission since publication of their manuscript. Under the m... more The authors have noticed an error and omission since publication of their manuscript. Under the methods section (sixth paragraph, second sentence) the text ''Each symptom/sign was assessed on scale of 0-3 (0 = absent, 1 = mild, 2 = moderate, 3 = severe) with a maximum score of 18.'' should read: ''Each symptom/sign was assessed on scale of 1-4 (1 = absent, 2 = mild, 3 = moderate, 4 = severe) with a maximum score of 18.'' The authors would also like to acknowledge Rajkumar Sethi for his contribution towards the study planning, implementation and execution.
Cureus, 2016
Background and objectives Excessive and prolonged work-related stress has always been a cause for... more Background and objectives Excessive and prolonged work-related stress has always been a cause for burnout among healthcare professionals. This has led to emotional, mental, and physical exhaustion. This survey was conducted to assess the burnout among medical practitioners using the abbreviated Maslach Burnout Inventory (aMBI) and Burnout Clinical Subtype Questionnaire (BCSQ-12) scales.
Cureus
Background and objectives The most widely used emergency medical services (EMS) model in India is... more Background and objectives The most widely used emergency medical services (EMS) model in India is the '108' emergency service which primarily functions as an emergency response system to attend patients in need of critical care, trauma and accident victims. This is an observational cross-sectional study which was conducted using a questionnaire that asks the participants about their awareness and opinion of the current EMS system. The results of this study will enable us to ascertain the level of awareness of EMS among the population and address any misconceptions if they exist. Materials and methods All participants had to complete a 24-item self-administered questionnaire consisting of eight socio-demographic questions and 16 questions based on the EMS system. Questions regarding the development of the '112' unified emergency service were also included. The convenient sampling method was used for data collection. The distribution of responses was examined using frequencies and percentages. Further analysis was done using the Chi-square test to compare responses between various subgroups based on the age, gender, profession, and level of education.
Background: Adverse drug reactions (ADRs) are a major cause of morbidity and hospitalizations hav... more Background: Adverse drug reactions (ADRs) are a major cause of morbidity and hospitalizations have consistently increased, leading to economic burden to developing countries like India. Identification of ADRs and their reporting pattern can provide useful information for their management. Aims and Objectives: The objective of the study was to assess the pattern of ADRs in tertiary care teaching hospital with respective to various parameters. Materials and Methods: The present study was an observational, prospective study. ADR reports of 40 patients were collected from various clinical departments of Dr. D. Y. Patil School of Medicine, Navi Mumbai. The ADRs were collected during January 2018-July 2018, with ADR reporting form of Central Drugs Standard Control Organization, New Delhi. Data were analyzed using descriptive statistics. Results: A total of 40 ADRs were reported during this study; the mean age of the patients being 43.14 (±2.27) years. Gender distribution of the patients showed 26 (65%) female preponderance. The majority of ADRs were implicated to pulmonary department 13 (32.5%) and least in OBGY 2 (5%). Using Naranjo's causality assessment scale, there were 24 (60%) probable, 12 (30%) possible, and 4 (10%) doubtful/unlikely causality of the ADR with the suspected offending drug. Conclusion: We conclude that antitubercular, injectable iron, pentavalent vaccines, and psychotropic drugs are responsible for most of the ADRs and middle-aged population are most commonly affected with ADR. Completeness score was an average of 32.2 ± 2.6. The completeness score can be improved if the reporter spends sometime considering its their moral responsibility.
Context: Intramuscular (IM) butorphanol can be a convenient postoperative analgesia compared to e... more Context: Intramuscular (IM) butorphanol can be a convenient postoperative analgesia compared to epidural (EP) route. Aims: Compare the efficacy and safety of IM vs EP butorphanol (1 mg/2 mg) as postoperative analgesia. Settings and design: A randomized-controlled study. Materials and methods: This study was conducted on 120 adult patients of either sex in the age group of 20-60 years, undergoing lower abdominal or lower limb surgeries (American Society of Anesthesiologists [ASA] class-I/II). Patients were randomized to butorphanol intramuscularly (IM group) or EP injection (EP group). Each group had two equal subgroups where patients received either 1 mg or 2 mg by the respective route. The primary outcomes were onset of analgesia, peak time of analgesia, and duration of analgesia. Pain was assessed on a 0-10 visual analog scale (VAS), and vital parameters were assessed at baseline and after 10, 20, 30, 60, 90, 120, and 180 minutes. Clinical safety was assessed by the adverse events. Results: The duration of analgesia provided by both the routes was comparable (293.0 minutes IM and 270.25 minutes EP). However, duration of analgesia was longer (p, 0.043) with 2 mg compared to 1 mg. Similarly, the onset of analgesia, pain scores, and peak time of analgesia were similar (p > 0.05) in the two groups. No differences in the hemodynamic parameters and respiratory rate were observed in the two groups. Higher incidence of all the side effects (sedation, somnolence, pruritus) was observed with IM administration. All side effects were clinically insignificant. Conclusion: Intramuscular butorphanol is as effective as an EP for the management of immediate postoperative pain. Keymessages: Intramuscular analgesics could be more convenient and safer compared to EP administration. Butorphanol administered by the IM route is as effective and safe compared to EP administration.
Unprecedented scientific development in recent decades have led to worsening of quality of life (... more Unprecedented scientific development in recent decades have led to worsening of quality of life (QOL) due to stress, functional disorders, unrest and psychological disturbances. QOL questionnaire is a standard tool in research to assess the usefulness of interventions on QOL. We observed the effect of yoga consisting of warm-ups, loosening exercises, Asanas, Pranayama, relaxation techniques and meditation on the QOL in dental professionals at a teaching dental institution in India. Our objective was to assess whether a 6-weeks integrated yoga approach helps improve the QOL in dental professionals. Twenty dental professionals (7 male/13 female) with mean age 39.45 were trained using a 45-minute module consisting of warm-ups, loosening exercises, Asanas, Pranayama, relaxation techniques and meditation. All participants attended 20 sessions over a 6-week period. A 26-item WHO QOL-BREF questionnaire was used to assess the QOL in 5 domains (global, physical, psychological, social and environmental). The change in the scores from baseline were analyzed using Wilcoxon sign rank test and the mean scores for total QOL-BREF scores were also compared for differences using paired 't' test. The improvement in the QOL after a 6-week yoga sessions are discussed in the results. Integrated approach of yoga at workplace improves the QOL in dental professionals especially in physical domain.
Background: Remineralization of noncavitated enamel is dependent on the bioavailability of calciu... more Background: Remineralization of noncavitated enamel is dependent on the bioavailability of calcium, phosphate, and hydroxyl ions in saliva. However, it is enhanced by the presence of fluoride. This study compared the remineralizing potential of three different topical fluoride agents. Materials and Methods: Fifteen extracted premolars were selected for the study. The crown of each tooth was longitudinally sectioned buccolingually and mesiodistally using a diamond disc so as to obtain sixty specimens which were embedded in acrylic molds. The specimens were immersed in demineralizing solution for 3 days. The specimens were randomly assigned to four groups, namely Duraphat fluoride varnish, ReminPro paste, ClinPro Tooth Crème, and control group (no surface treatment). A pH cycling includes alternate demineralization and remineralization. Surface mean hardness (SMH) was recorded with 50 g load for 5 s using VHN machine at baseline, after demineralization and pH cycling. The four groups were compared for difference in SMH using one-way ANOVA followed by Tukey-Kramer test. All testing was done with alpha 0.05. Results: SMH recovery results for ClinPro, Duraphat, and ReminPro were 54.88%, 43.42%, and 26.86%, respectively. The difference in the percentage SMH recovery for ClinPro paste was better than Duraphat and ReminPro, and this difference was statistically significant (P < 0.05). Conclusions: ClinPro tooth Crème showed the best remineralization potential among the three materials tested followed by Duraphat and ReminPro.
ARTICLE INFO ABSTRACT Objective: To assess the number of Private Dental Practitioners (PDPs) prac... more ARTICLE INFO ABSTRACT Objective: To assess the number of Private Dental Practitioners (PDPs) practicing and not practicing dental implantology and to evaluate their knowledge, awareness and practice about implant dentistry. Methods: A self-structured questionnaire was distributed to 200 PDPs of Navi Mumbai. The questionnaire covered general basic information and assessed the knowledge, attitude and practice of PDPs regarding implant dentistry. Descriptive analysis was carried out for the responses. Results: Out of 200 PDPs 45% were Bachelor of Dental Surgery(BDS) and most of them were not practicing implant dentistry due to lack of skills, while 55% were Master of Dental Surgery (MDS) in various fields and were practicing implant dentistry by themselves.
Context: Zenith points are the most apical position of the cervical tooth margin where the gingiv... more Context: Zenith points are the most apical position of the cervical tooth margin where the gingiva is most scalloped. To establish the appropriate gingival zenith is of utmost importance in the field of esthetic dentistry. Any alterations in symmetry and gingival contour can significantly have impact on harmony of both natural and artificial teeth. Aims: To measure the deviation of Gingival zenith (GZ) of maxillary anterior with the Vertical Bisected Midline (VBM) and Apico coronal displacement of lateral incisor zenith from Gingival Zenith Level (GZL) of central incisor and canine Settings and Design: 50 patient was enrolled in our study who satisfy the inclusion and exclusion criteria. Six maxillary anterior teeth was assessed for each subject and hence the total sample size was 300 teeth.
Journal of Yoga and Physiotherapy
Journal of Obstetrics and Gynaecology Research
The Physician
Poster presented at Forum for Interdisciplinary Research in Medicine, Science & Technology Confer... more Poster presented at Forum for Interdisciplinary Research in Medicine, Science & Technology Conference, Moscow 2020 Peer reviewed by JS Bamrah, Ananthakrishnan Raghuraman, Soumit Dasgupta & Jyothi Srinivasan
Cureus
Background Stress, anxiety and impeded sleep are a frequent feature of life in modern societies. ... more Background Stress, anxiety and impeded sleep are a frequent feature of life in modern societies. Across socioeconomic strata, stress, anxiety and ineffective sleep detract from healthful living and serve as precursors of various ailments. The use of herbs to offset these antecedents and outcomes has greatly increased in recent years. Ashwagandha, an adaptogenic Ayurvedic herb, has been often used to combat and reduce stress and thereby enhance general wellbeing. While there have been other studies documenting the use of Ashwagandha for stress resistance, this is the first study to use a high-concentration root extract while also varying the dosage substantially. Therefore, this is the first study to offer insight into dose-response of a high concentration root extract.
Advances in Therapy
The authors have noticed an error and omission since publication of their manuscript. Under the m... more The authors have noticed an error and omission since publication of their manuscript. Under the methods section (sixth paragraph, second sentence) the text ''Each symptom/sign was assessed on scale of 0-3 (0 = absent, 1 = mild, 2 = moderate, 3 = severe) with a maximum score of 18.'' should read: ''Each symptom/sign was assessed on scale of 1-4 (1 = absent, 2 = mild, 3 = moderate, 4 = severe) with a maximum score of 18.'' The authors would also like to acknowledge Rajkumar Sethi for his contribution towards the study planning, implementation and execution.
Cureus, 2016
Background and objectives Excessive and prolonged work-related stress has always been a cause for... more Background and objectives Excessive and prolonged work-related stress has always been a cause for burnout among healthcare professionals. This has led to emotional, mental, and physical exhaustion. This survey was conducted to assess the burnout among medical practitioners using the abbreviated Maslach Burnout Inventory (aMBI) and Burnout Clinical Subtype Questionnaire (BCSQ-12) scales.
Cureus
Background and objectives The most widely used emergency medical services (EMS) model in India is... more Background and objectives The most widely used emergency medical services (EMS) model in India is the '108' emergency service which primarily functions as an emergency response system to attend patients in need of critical care, trauma and accident victims. This is an observational cross-sectional study which was conducted using a questionnaire that asks the participants about their awareness and opinion of the current EMS system. The results of this study will enable us to ascertain the level of awareness of EMS among the population and address any misconceptions if they exist. Materials and methods All participants had to complete a 24-item self-administered questionnaire consisting of eight socio-demographic questions and 16 questions based on the EMS system. Questions regarding the development of the '112' unified emergency service were also included. The convenient sampling method was used for data collection. The distribution of responses was examined using frequencies and percentages. Further analysis was done using the Chi-square test to compare responses between various subgroups based on the age, gender, profession, and level of education.
Background: Adverse drug reactions (ADRs) are a major cause of morbidity and hospitalizations hav... more Background: Adverse drug reactions (ADRs) are a major cause of morbidity and hospitalizations have consistently increased, leading to economic burden to developing countries like India. Identification of ADRs and their reporting pattern can provide useful information for their management. Aims and Objectives: The objective of the study was to assess the pattern of ADRs in tertiary care teaching hospital with respective to various parameters. Materials and Methods: The present study was an observational, prospective study. ADR reports of 40 patients were collected from various clinical departments of Dr. D. Y. Patil School of Medicine, Navi Mumbai. The ADRs were collected during January 2018-July 2018, with ADR reporting form of Central Drugs Standard Control Organization, New Delhi. Data were analyzed using descriptive statistics. Results: A total of 40 ADRs were reported during this study; the mean age of the patients being 43.14 (±2.27) years. Gender distribution of the patients showed 26 (65%) female preponderance. The majority of ADRs were implicated to pulmonary department 13 (32.5%) and least in OBGY 2 (5%). Using Naranjo's causality assessment scale, there were 24 (60%) probable, 12 (30%) possible, and 4 (10%) doubtful/unlikely causality of the ADR with the suspected offending drug. Conclusion: We conclude that antitubercular, injectable iron, pentavalent vaccines, and psychotropic drugs are responsible for most of the ADRs and middle-aged population are most commonly affected with ADR. Completeness score was an average of 32.2 ± 2.6. The completeness score can be improved if the reporter spends sometime considering its their moral responsibility.
Context: Intramuscular (IM) butorphanol can be a convenient postoperative analgesia compared to e... more Context: Intramuscular (IM) butorphanol can be a convenient postoperative analgesia compared to epidural (EP) route. Aims: Compare the efficacy and safety of IM vs EP butorphanol (1 mg/2 mg) as postoperative analgesia. Settings and design: A randomized-controlled study. Materials and methods: This study was conducted on 120 adult patients of either sex in the age group of 20-60 years, undergoing lower abdominal or lower limb surgeries (American Society of Anesthesiologists [ASA] class-I/II). Patients were randomized to butorphanol intramuscularly (IM group) or EP injection (EP group). Each group had two equal subgroups where patients received either 1 mg or 2 mg by the respective route. The primary outcomes were onset of analgesia, peak time of analgesia, and duration of analgesia. Pain was assessed on a 0-10 visual analog scale (VAS), and vital parameters were assessed at baseline and after 10, 20, 30, 60, 90, 120, and 180 minutes. Clinical safety was assessed by the adverse events. Results: The duration of analgesia provided by both the routes was comparable (293.0 minutes IM and 270.25 minutes EP). However, duration of analgesia was longer (p, 0.043) with 2 mg compared to 1 mg. Similarly, the onset of analgesia, pain scores, and peak time of analgesia were similar (p > 0.05) in the two groups. No differences in the hemodynamic parameters and respiratory rate were observed in the two groups. Higher incidence of all the side effects (sedation, somnolence, pruritus) was observed with IM administration. All side effects were clinically insignificant. Conclusion: Intramuscular butorphanol is as effective as an EP for the management of immediate postoperative pain. Keymessages: Intramuscular analgesics could be more convenient and safer compared to EP administration. Butorphanol administered by the IM route is as effective and safe compared to EP administration.
Unprecedented scientific development in recent decades have led to worsening of quality of life (... more Unprecedented scientific development in recent decades have led to worsening of quality of life (QOL) due to stress, functional disorders, unrest and psychological disturbances. QOL questionnaire is a standard tool in research to assess the usefulness of interventions on QOL. We observed the effect of yoga consisting of warm-ups, loosening exercises, Asanas, Pranayama, relaxation techniques and meditation on the QOL in dental professionals at a teaching dental institution in India. Our objective was to assess whether a 6-weeks integrated yoga approach helps improve the QOL in dental professionals. Twenty dental professionals (7 male/13 female) with mean age 39.45 were trained using a 45-minute module consisting of warm-ups, loosening exercises, Asanas, Pranayama, relaxation techniques and meditation. All participants attended 20 sessions over a 6-week period. A 26-item WHO QOL-BREF questionnaire was used to assess the QOL in 5 domains (global, physical, psychological, social and environmental). The change in the scores from baseline were analyzed using Wilcoxon sign rank test and the mean scores for total QOL-BREF scores were also compared for differences using paired 't' test. The improvement in the QOL after a 6-week yoga sessions are discussed in the results. Integrated approach of yoga at workplace improves the QOL in dental professionals especially in physical domain.
Background: Remineralization of noncavitated enamel is dependent on the bioavailability of calciu... more Background: Remineralization of noncavitated enamel is dependent on the bioavailability of calcium, phosphate, and hydroxyl ions in saliva. However, it is enhanced by the presence of fluoride. This study compared the remineralizing potential of three different topical fluoride agents. Materials and Methods: Fifteen extracted premolars were selected for the study. The crown of each tooth was longitudinally sectioned buccolingually and mesiodistally using a diamond disc so as to obtain sixty specimens which were embedded in acrylic molds. The specimens were immersed in demineralizing solution for 3 days. The specimens were randomly assigned to four groups, namely Duraphat fluoride varnish, ReminPro paste, ClinPro Tooth Crème, and control group (no surface treatment). A pH cycling includes alternate demineralization and remineralization. Surface mean hardness (SMH) was recorded with 50 g load for 5 s using VHN machine at baseline, after demineralization and pH cycling. The four groups were compared for difference in SMH using one-way ANOVA followed by Tukey-Kramer test. All testing was done with alpha 0.05. Results: SMH recovery results for ClinPro, Duraphat, and ReminPro were 54.88%, 43.42%, and 26.86%, respectively. The difference in the percentage SMH recovery for ClinPro paste was better than Duraphat and ReminPro, and this difference was statistically significant (P < 0.05). Conclusions: ClinPro tooth Crème showed the best remineralization potential among the three materials tested followed by Duraphat and ReminPro.
ARTICLE INFO ABSTRACT Objective: To assess the number of Private Dental Practitioners (PDPs) prac... more ARTICLE INFO ABSTRACT Objective: To assess the number of Private Dental Practitioners (PDPs) practicing and not practicing dental implantology and to evaluate their knowledge, awareness and practice about implant dentistry. Methods: A self-structured questionnaire was distributed to 200 PDPs of Navi Mumbai. The questionnaire covered general basic information and assessed the knowledge, attitude and practice of PDPs regarding implant dentistry. Descriptive analysis was carried out for the responses. Results: Out of 200 PDPs 45% were Bachelor of Dental Surgery(BDS) and most of them were not practicing implant dentistry due to lack of skills, while 55% were Master of Dental Surgery (MDS) in various fields and were practicing implant dentistry by themselves.
Context: Zenith points are the most apical position of the cervical tooth margin where the gingiv... more Context: Zenith points are the most apical position of the cervical tooth margin where the gingiva is most scalloped. To establish the appropriate gingival zenith is of utmost importance in the field of esthetic dentistry. Any alterations in symmetry and gingival contour can significantly have impact on harmony of both natural and artificial teeth. Aims: To measure the deviation of Gingival zenith (GZ) of maxillary anterior with the Vertical Bisected Midline (VBM) and Apico coronal displacement of lateral incisor zenith from Gingival Zenith Level (GZL) of central incisor and canine Settings and Design: 50 patient was enrolled in our study who satisfy the inclusion and exclusion criteria. Six maxillary anterior teeth was assessed for each subject and hence the total sample size was 300 teeth.