Hüseyin Akdeniz | Yuzuncu Yil University (original) (raw)
Papers by Hüseyin Akdeniz
Current Medical Imaging Formerly: Current Medical Imaging Reviews
Background: Chronic pelvic pain (CPP) is a common complaint in women, and is the key factor in th... more Background: Chronic pelvic pain (CPP) is a common complaint in women, and is the key factor in the diagnosis of pelvic congestion syndrome (PCS). Introduction: Consecutive abdominal and pelvic computed tomography (CT) scans in adult female patients not diagnosed with PCS and collected over a period of 3 years were evaluated retrospectively to determine the prevalence of underestimated pelvic congestion (PC). Methods: 500 consecutive abdominal and pelvic CT scans collected from female patients aged 18-80 years were retrospectively analyzed for the presence of PC. Results: 90 of the CT scans examined showed the presence of PC (18 %). These patients were divided into two groups: Group I had 52 scans with unilateral PC, while Group II had 38 scans with the bilateral enlarged ovarian vein (OV). Left and right OV diameters were measured as 7.14±2.15 and 5.56±1.87 mm, respectively. Co-occurrence of additional vascular anomalies, such as nutcracker-type compression of the left renal vein, a...
Acta Radiologica
Background Idiopathic granulomatous mastitis (IGM) is a chronic, unpleasant autoimmune inflammato... more Background Idiopathic granulomatous mastitis (IGM) is a chronic, unpleasant autoimmune inflammatory condition and is clinically and radiologically often confused with breast malignancy. Purpose To investigate the contributions of qualitative and quantitative aspects of acoustic radiation force impulse (ARFI) elastography to the differential diagnosis between IGM and invasive ductal carcinoma (IDC) in the breast. Material and Methods Ninety-four women with IDC and 39 with IGM were included in the study. Shear wave velocity (SWV) was calculated for all lesions using quantitative elastography. Next, each lesion’s correspondence on qualitative elastographic images to those on the B-mode images was evaluated: pattern 1, no findings on elastography images; pattern 2, lesions that were bright inside; pattern 3, lesions that contained both bright and dark areas; and pattern 4, lesions that were dark inside. Pattern 4 was subdivided into 4a (dark area same size as lesion) and 4b (dark area l...
Eastern Journal Of Medicine
Eastern Journal Of Medicine
The aim of this study is to evaluate results of the screening program of the development al dyspl... more The aim of this study is to evaluate results of the screening program of the development al dysplasia of the hip (DDH) examined in newborn period. The problems encountered in the applicability of the early screening program were e valuated. By interviewing with the family of 1680 newborns born in our institution or referred, the information was given about the DDH and its risk factors, obtained results were recorded. The families were told to bring their babies for examination and hip ultrasound at the 3 rd or 4 th week of birth. In addition, all the parents were called by telephone the day prior to their appointments. Five hundred and thirty-six babies (31.3%) were brought to the first appointment. Forty-two hips (3.9%) of the 30 infants (5.6%) were detected as dislocated (Type 2c, D, 3). The 8 of these 30 patients (26.7%) whom the treatment was started were brought for the second control. Asymmetry of th igh folds was positive in the highest rate as the finding of the examination in the infants brought to the appointment. The rate of swaddling at the first appointment was found to be 74.2%. Surprisingly, less than one third of children were brought to ultr asound examination at first control. Similarly, about 3/4 of the parents continued to use swaddling for their babies. For the success of national DDH screening program, additional precautions must be taken to ensure the participation of the families and re lease of the swaddling.
Acta Radiologica
Background X-rays are defined as ionizing radiation and hydrolyze the water, causing free radical... more Background X-rays are defined as ionizing radiation and hydrolyze the water, causing free radical formation. Oxidative stress is the damage that occurs in cells due to the lack of antioxidants, which detoxifies them, with the increased production of free radicals that occur during normal cellular metabolism. Purpose To examine the acute effects of computed tomography (CT), i.e. ionizing radiation, on oxidative stress and antioxidant defense mechanisms. Material and Methods The study included a total of 53 patients that were selected among the patients that underwent non-contrast full-body CT. Malondialdehyde (MDA) and reduced glutathione (GSH) levels and superoxide dismutase (SOD) and catalase (CAT) activities were investigated in blood samples taken from patients. Results The post-scan levels of MDA increased significantly while the post-scan levels of GSH, SOD, and CAT decreased significantly compared to their pre-scan levels. Conclusion CT, which is a widely used X-ray imaging te...
Eastern Journal Of Medicine
Materials and Methods Subjects: This study was carried out at Chest Diseases Clinic (14 bed) and ... more Materials and Methods Subjects: This study was carried out at Chest Diseases Clinic (14 bed) and Anesthesiology Intensive Care Unit (15 bed) of Dursun Odabaş Medical Center of Yüzüncü Yıl University and Chest Diseases Department (10 bed) and Intensive Care Unit (12 bed) of Lokman Hekim Hospital in Van, Turkey. The approval of Ethics Committee of Yüzüncü Yıl University was obtained. The records of 77 adult patients, who have been hospitalized with suspicion of swine H1N1 virus pneumonia, were retrospectively evaluated. By using the reverse transcriptase-polymerase chain reaction (RT-PCR) assay in their pharyngeal swab, 17 patients, who have been confirmed to have
Van Medical Journal
Basit faringeal cerrahi prosedürler sırasında internal karotis arter zedelenmeleri kanama riski a... more Basit faringeal cerrahi prosedürler sırasında internal karotis arter zedelenmeleri kanama riski açısından felaketle sonuçlanabilir. Bu çalışmada internal karotis arter servikal segmenti mediale dispozisyonu ve bu varyasyonun "rutin" farengeal cerrahi işlemler açısından olası risk faktörlerini değerlendirmektir.
Van Medical Journal
Objective: We aimed to investigate the contribution of strain elastosonography to the distinction... more Objective: We aimed to investigate the contribution of strain elastosonography to the distinction of benign and malignant thyroid nodules. Materials and Methods: The retrospective study included 135 patients who were detected with thyroid nodules on ultrasonography and then underwent fineneedle aspiration biopsy (FNAB). Semi-quantitative strain elastographic evaluation was performed and mean strain ratio was calculated for each nodule. The elastograms were classified using the Tsukuba fivepattern visual scoring system. Accordingly, the lesions with scores 1 and 2 were accepted as soft nodules (benign), score 3 as moderately hard nodules, and scores 4 and 5 as hard nodules (malignant). The nodules were divided as benign and malignant depending on the histopathological results. The FNAB results were compared with elasticity scores. Results: The patients included 18 (13.3%) men and 117 (86.7%) women. Of the 135 lesions, 113 (83.7%) were benign and 22 (16.3%) were malignant. Strain ratio value was statistically higher in malignant lesions compared to benign lesions (p<0.01). When compared with the histopathological results, elastosonography scoring had a sensitivity of 81.8%, specificity of 89.4%, positive predictive value (PPV) of 96.2%, and negative predictive value (NPV) of 64.7%. However, compared with the strain ratio values, elastosonography scoring had a sensitivity of 77.3%, specificity of 87.6%, PPV of 95.2%, and NPV of 54.8% at a cutoff point of 4.850. Conclusion: Elastosonography is highly effective in the differentiation of benign and malignant lesions.
Journal of medical ultrasonics (2001), 2018
The aim of the present study was to quantify the stiffness of the median nerve (MN) at the carpal... more The aim of the present study was to quantify the stiffness of the median nerve (MN) at the carpal tunnel inlet by acoustic radiation force impulse (ARFI) elastography and to evaluate whether ARFI can be used in diagnosis and staging of carpal tunnel syndrome (CTS). Sonographic examinations of 96 wrists in 50 patients were included in the study. The cross-sectional area and stiffness of the MN were quantitatively measured by B-mode ultrasonography (USG) and ARFI. The findings of CTS were assigned to four groups: (I) normal (n = 21), (II) mild (n = 39), (III) moderate (n = 38), and (IV) severe (n = 19). The differences between CTS patients and controls and the differences in electrodiagnostic tests among subgroups were statistically compared. ROC analysis was performed to determine the cut-off values between subgroups. Bilateral CTS was present in 46 patients (92 wrists) and unilateral CTS in four patients. Of the 96 nerves in the 50 symptomatic "idiopathic CTS" patients (48...
Medical science monitor : international medical journal of experimental and clinical research, Jan 11, 2018
BACKGROUND In the present study, the role and efficiency of strain elastography (SE) were evaluat... more BACKGROUND In the present study, the role and efficiency of strain elastography (SE) were evaluated in diagnosis and staging of acute appendicitis in pediatric patients. MATERIAL AND METHODS We enrolled 225 pediatric patients with suspected clinical and laboratory findings of acute appendicitis. Gray-scale sonographic findings were recorded and staging was made by the colorization method of SE imaging. Appendectomy was performed in all patients and the results of the surgical pathology were compared with the imaging findings. The sensitivity, specificity, and accuracy of SE imaging were determined in terms of evaluating the "acute appendicitis". RESULTS Sonographic evaluation revealed acute appendicitis in 100 patients. Regarding the SE analysis, cases with appendicitis were classified into 3 groups as: mild (n=17), moderate (n=39), and severe (n=44). The pathological evaluation revealed 95 different stages of appendicitis and normal appendix in 5 cases: acute focal (n=10)...
Kafkas Journal of Medical Sciences
Aim: We aimed to investigate the efficacy and tolerability of modified FOLFIRI-Bevacizumab (mFOLF... more Aim: We aimed to investigate the efficacy and tolerability of modified FOLFIRI-Bevacizumab (mFOLFIRI-B) regime in the secondline treatment of metastatic colorectal cancer (mCRC) patients who received oxaliplatin-based regimen in the first-line treatment. Material and Method: The patients treated with mFOLFIRI-B regimen in second-line therapy who had progressed after oxaliplatin-based chemotherapy were included in this study. The datas of toxicity and efficacy of the regimen were retrospectively evaluated. Results: Total 172 mCRC patients had received mFOLFIRI-B regime in the second-line treatment. 39.5% objective response rate, 9.0 months (7.6 to 10.3) median progression-free survival, 19.0 months (15.1 to 26.2) median overall survival were found. Grade 3/4 toxicity was observed in 33.7%. Grade 3/4 hematologic toxicity was most frequently observed toxicity (31.9%). Conclusion: mFOLFIRI-B is an efficient and safe regimen for the second-line treatment of mCRC patients after the oxaliplatinbased regimen.
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2016
The incidence of all malignant tumours during pregnancy is extremely rare and esophageal carcinom... more The incidence of all malignant tumours during pregnancy is extremely rare and esophageal carcinoma ranges from 0.07 to 0.1% of all malignant neoplasms. The physiological changes during pregnancy frequently mask the complaints and symptoms related to the disease. The physical and physiological clinical conditions limit the diagnostic approaches. Therefore, the stage of cancer at the time of diagnosis is usually advanced. The management with cancer surgery and chemotherapy regimens must be modified in pregnant women in order to minimize fetal and maternal risks. Here, we report a very rare case of metastatic esophagus cancer in a 39-year-old woman with 28 weeks of pregnancy and aim to show the ultrasound (USG) and magnetic resonance imaging (MRI) findings with treatment and follow up management.
Case Reports in Obstetrics and Gynecology, 2015
Introduction. Vulvar cyst in adolescent girls is very uncommon. Epidermoid cyst can be seen in ma... more Introduction. Vulvar cyst in adolescent girls is very uncommon. Epidermoid cyst can be seen in many sites including face, trunk, and extremities but its occurrence in vulva is uncommon. This is the first case of epidermoid cyst of vulva reported in an adolescent girl.Case. A 17-year-old, adolescent girl admitted to our gynecology outpatient clinic with a complaint of painful and palpable mass in her vulva. On examination, a giant mass located in left vulva and labia majora with 11 cm in diameter was seen. The magnetic resonance imaging (MRI) showed a well-defined cystic mass without contrast enhancement. The surgery was advised to the patient and the pathologic examination of mass revealed vulvar epidermoid cyst.Discussion. Vulvar cysts generally grow slowly and the main etiologies are vulvar trauma and surgical interventions including episiotomy and female circumcision in some culture. The exact treatment is total surgical excision and pathologic examination. MRI is an important im...
![Research paper thumbnail of [Value of diffusion weighted imaging in diagnosis of nodular lesions of thyroid: a preliminary study]](https://attachments.academia-assets.com/72875739/thumbnails/1.jpg)
](Zhonghua yi xue za zhi, Jan 21, 2010
To investigate the value of magnetic resonance diffusion weighted imaging (DWI) in the differenti... more To investigate the value of magnetic resonance diffusion weighted imaging (DWI) in the differential diagnoses of malignant and benign thyroid lesions. Using echo planner imaging sequence with b value of 0, 100, 200, 300 and 400 s/mm(2) respectively, DWI was performed in 60 patients of focal thyroid lesions. The diagnosis was confirmed by pathological examination (benign, n = 30; malignant, n = 30). Apparent diffusion coefficient (ADC) values were measured. The differences were analyzed between two groups. With b value of 0, 100, 200, 300 and 400 s/mm(2) respectively, there were statistical differences in ADC values between benign and malignant lesions. The ADC value of malignant lesions was smaller than that of benign lesions (P < 0.05). Among different b values, 400 s/mm(2) was the most optimal one to diagnose thyroid nodular lesions. DWI with a b value of 400 s/mm(2) had a proper signal-to-noise ratio (SNO). And ADC value could be measured correctly. With a b value of 400 s/mm(...
Case reports in medicine, 2010
Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is an extremely rare complica... more Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is an extremely rare complication of infectious diseases. A rare case of brucellosis complicated by syndrome of inappropriate secretion of antidiuretic hormone (SIADH) cholestasis and pericardial involvement is reported. A 27-year-old woman was admitted for fever, abdominal pain, and scleral icterus. Her medical history revealed no recent use of diuretic agents. In addition to cholestasis and elevated liver enzymes, euvolemic hyponatremia, hypouricemia, low plasma osmolality, and high urinary osmolality were also detected. Surrenal and thyroid tests were also within normal range. Echocardiography revealed minimal pericardial effusion with normal cardiac functions. The final diagnosis was SIADH due to Brucellosis. Hyponatremia, cholestasis, and pericardial disease were resolved with effective antibrucellar treatment with streptomycine and doxycycline. After completing treatment of brucellosis, there was not any more ...
Case Reports in Infectious Diseases, 2015
Thyroid gland infection, although rare, may be a life threatening disease. Thyroid abscess, arisi... more Thyroid gland infection, although rare, may be a life threatening disease. Thyroid abscess, arising from acute suppurative thyroiditis (AST), is a rare clinic condition depending on widespread use of antibiotics. Infection may involve one or both lobes and abscess formation may not be apparent until late stage of the progress of illness. Thyroid left lobe is more often affected than the right one. Brucellosis, especially obvious in endemic areas, is a widely seen zoonosis around the world. Although brucella infection can affect many organs through various complications, thyroid gland infection is rare. We aimed to present ultrasonography (USG) and magnetic resonance images (MRI) of a case with an acute thyroiditis which rapidly developed and grew fast on the left half of the neck during the first postpartum month. As far as we know from literature reviewing, our case is the first case report of a thyroid abscess arising from brucella infection which is developed in first postpartum ...
Case Reports in Medicine, 2010
Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is an extremely rare complica... more Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is an extremely rare complication of infectious diseases. A rare case of brucellosis complicated by syndrome of inappropriate secretion of antidiuretic hormone (SIADH) cholestasis and pericardial involvement is reported. A 27-year-old woman was admitted for fever, abdominal pain, and scleral icterus. Her medical history revealed no recent use of diuretic agents. In addition to cholestasis and elevated liver enzymes, euvolemic hyponatremia, hypouricemia, low plasma osmolality, and high urinary osmolality were also detected. Surrenal and thyroid tests were also within normal range. Echocardiography revealed minimal pericardial effusion with normal cardiac functions. The final diagnosis was SIADH due to Brucellosis. Hyponatremia, cholestasis, and pericardial disease were resolved with effective antibrucellar treatment with streptomycine and doxycycline. After completing treatment of brucellosis, there was not any more ...
Journal of Clinical Imaging Science, 2014
Ectopic neurohypophysis is a pituitary gland abnormality, which can accompany growth hormone defi... more Ectopic neurohypophysis is a pituitary gland abnormality, which can accompany growth hormone deficiency associated with dwarfism. Here we present magnetic resonance imaging (MRI) findings of a rare case of ectopic neurohypophysis, corpus callosum dysgenesis, and periventricular neuronal heterotopia coexisting, with a review of the literature.
Current Medical Imaging Formerly: Current Medical Imaging Reviews
Background: Chronic pelvic pain (CPP) is a common complaint in women, and is the key factor in th... more Background: Chronic pelvic pain (CPP) is a common complaint in women, and is the key factor in the diagnosis of pelvic congestion syndrome (PCS). Introduction: Consecutive abdominal and pelvic computed tomography (CT) scans in adult female patients not diagnosed with PCS and collected over a period of 3 years were evaluated retrospectively to determine the prevalence of underestimated pelvic congestion (PC). Methods: 500 consecutive abdominal and pelvic CT scans collected from female patients aged 18-80 years were retrospectively analyzed for the presence of PC. Results: 90 of the CT scans examined showed the presence of PC (18 %). These patients were divided into two groups: Group I had 52 scans with unilateral PC, while Group II had 38 scans with the bilateral enlarged ovarian vein (OV). Left and right OV diameters were measured as 7.14±2.15 and 5.56±1.87 mm, respectively. Co-occurrence of additional vascular anomalies, such as nutcracker-type compression of the left renal vein, a...
Acta Radiologica
Background Idiopathic granulomatous mastitis (IGM) is a chronic, unpleasant autoimmune inflammato... more Background Idiopathic granulomatous mastitis (IGM) is a chronic, unpleasant autoimmune inflammatory condition and is clinically and radiologically often confused with breast malignancy. Purpose To investigate the contributions of qualitative and quantitative aspects of acoustic radiation force impulse (ARFI) elastography to the differential diagnosis between IGM and invasive ductal carcinoma (IDC) in the breast. Material and Methods Ninety-four women with IDC and 39 with IGM were included in the study. Shear wave velocity (SWV) was calculated for all lesions using quantitative elastography. Next, each lesion’s correspondence on qualitative elastographic images to those on the B-mode images was evaluated: pattern 1, no findings on elastography images; pattern 2, lesions that were bright inside; pattern 3, lesions that contained both bright and dark areas; and pattern 4, lesions that were dark inside. Pattern 4 was subdivided into 4a (dark area same size as lesion) and 4b (dark area l...
Eastern Journal Of Medicine
Eastern Journal Of Medicine
The aim of this study is to evaluate results of the screening program of the development al dyspl... more The aim of this study is to evaluate results of the screening program of the development al dysplasia of the hip (DDH) examined in newborn period. The problems encountered in the applicability of the early screening program were e valuated. By interviewing with the family of 1680 newborns born in our institution or referred, the information was given about the DDH and its risk factors, obtained results were recorded. The families were told to bring their babies for examination and hip ultrasound at the 3 rd or 4 th week of birth. In addition, all the parents were called by telephone the day prior to their appointments. Five hundred and thirty-six babies (31.3%) were brought to the first appointment. Forty-two hips (3.9%) of the 30 infants (5.6%) were detected as dislocated (Type 2c, D, 3). The 8 of these 30 patients (26.7%) whom the treatment was started were brought for the second control. Asymmetry of th igh folds was positive in the highest rate as the finding of the examination in the infants brought to the appointment. The rate of swaddling at the first appointment was found to be 74.2%. Surprisingly, less than one third of children were brought to ultr asound examination at first control. Similarly, about 3/4 of the parents continued to use swaddling for their babies. For the success of national DDH screening program, additional precautions must be taken to ensure the participation of the families and re lease of the swaddling.
Acta Radiologica
Background X-rays are defined as ionizing radiation and hydrolyze the water, causing free radical... more Background X-rays are defined as ionizing radiation and hydrolyze the water, causing free radical formation. Oxidative stress is the damage that occurs in cells due to the lack of antioxidants, which detoxifies them, with the increased production of free radicals that occur during normal cellular metabolism. Purpose To examine the acute effects of computed tomography (CT), i.e. ionizing radiation, on oxidative stress and antioxidant defense mechanisms. Material and Methods The study included a total of 53 patients that were selected among the patients that underwent non-contrast full-body CT. Malondialdehyde (MDA) and reduced glutathione (GSH) levels and superoxide dismutase (SOD) and catalase (CAT) activities were investigated in blood samples taken from patients. Results The post-scan levels of MDA increased significantly while the post-scan levels of GSH, SOD, and CAT decreased significantly compared to their pre-scan levels. Conclusion CT, which is a widely used X-ray imaging te...
Eastern Journal Of Medicine
Materials and Methods Subjects: This study was carried out at Chest Diseases Clinic (14 bed) and ... more Materials and Methods Subjects: This study was carried out at Chest Diseases Clinic (14 bed) and Anesthesiology Intensive Care Unit (15 bed) of Dursun Odabaş Medical Center of Yüzüncü Yıl University and Chest Diseases Department (10 bed) and Intensive Care Unit (12 bed) of Lokman Hekim Hospital in Van, Turkey. The approval of Ethics Committee of Yüzüncü Yıl University was obtained. The records of 77 adult patients, who have been hospitalized with suspicion of swine H1N1 virus pneumonia, were retrospectively evaluated. By using the reverse transcriptase-polymerase chain reaction (RT-PCR) assay in their pharyngeal swab, 17 patients, who have been confirmed to have
Van Medical Journal
Basit faringeal cerrahi prosedürler sırasında internal karotis arter zedelenmeleri kanama riski a... more Basit faringeal cerrahi prosedürler sırasında internal karotis arter zedelenmeleri kanama riski açısından felaketle sonuçlanabilir. Bu çalışmada internal karotis arter servikal segmenti mediale dispozisyonu ve bu varyasyonun "rutin" farengeal cerrahi işlemler açısından olası risk faktörlerini değerlendirmektir.
Van Medical Journal
Objective: We aimed to investigate the contribution of strain elastosonography to the distinction... more Objective: We aimed to investigate the contribution of strain elastosonography to the distinction of benign and malignant thyroid nodules. Materials and Methods: The retrospective study included 135 patients who were detected with thyroid nodules on ultrasonography and then underwent fineneedle aspiration biopsy (FNAB). Semi-quantitative strain elastographic evaluation was performed and mean strain ratio was calculated for each nodule. The elastograms were classified using the Tsukuba fivepattern visual scoring system. Accordingly, the lesions with scores 1 and 2 were accepted as soft nodules (benign), score 3 as moderately hard nodules, and scores 4 and 5 as hard nodules (malignant). The nodules were divided as benign and malignant depending on the histopathological results. The FNAB results were compared with elasticity scores. Results: The patients included 18 (13.3%) men and 117 (86.7%) women. Of the 135 lesions, 113 (83.7%) were benign and 22 (16.3%) were malignant. Strain ratio value was statistically higher in malignant lesions compared to benign lesions (p<0.01). When compared with the histopathological results, elastosonography scoring had a sensitivity of 81.8%, specificity of 89.4%, positive predictive value (PPV) of 96.2%, and negative predictive value (NPV) of 64.7%. However, compared with the strain ratio values, elastosonography scoring had a sensitivity of 77.3%, specificity of 87.6%, PPV of 95.2%, and NPV of 54.8% at a cutoff point of 4.850. Conclusion: Elastosonography is highly effective in the differentiation of benign and malignant lesions.
Journal of medical ultrasonics (2001), 2018
The aim of the present study was to quantify the stiffness of the median nerve (MN) at the carpal... more The aim of the present study was to quantify the stiffness of the median nerve (MN) at the carpal tunnel inlet by acoustic radiation force impulse (ARFI) elastography and to evaluate whether ARFI can be used in diagnosis and staging of carpal tunnel syndrome (CTS). Sonographic examinations of 96 wrists in 50 patients were included in the study. The cross-sectional area and stiffness of the MN were quantitatively measured by B-mode ultrasonography (USG) and ARFI. The findings of CTS were assigned to four groups: (I) normal (n = 21), (II) mild (n = 39), (III) moderate (n = 38), and (IV) severe (n = 19). The differences between CTS patients and controls and the differences in electrodiagnostic tests among subgroups were statistically compared. ROC analysis was performed to determine the cut-off values between subgroups. Bilateral CTS was present in 46 patients (92 wrists) and unilateral CTS in four patients. Of the 96 nerves in the 50 symptomatic "idiopathic CTS" patients (48...
Medical science monitor : international medical journal of experimental and clinical research, Jan 11, 2018
BACKGROUND In the present study, the role and efficiency of strain elastography (SE) were evaluat... more BACKGROUND In the present study, the role and efficiency of strain elastography (SE) were evaluated in diagnosis and staging of acute appendicitis in pediatric patients. MATERIAL AND METHODS We enrolled 225 pediatric patients with suspected clinical and laboratory findings of acute appendicitis. Gray-scale sonographic findings were recorded and staging was made by the colorization method of SE imaging. Appendectomy was performed in all patients and the results of the surgical pathology were compared with the imaging findings. The sensitivity, specificity, and accuracy of SE imaging were determined in terms of evaluating the "acute appendicitis". RESULTS Sonographic evaluation revealed acute appendicitis in 100 patients. Regarding the SE analysis, cases with appendicitis were classified into 3 groups as: mild (n=17), moderate (n=39), and severe (n=44). The pathological evaluation revealed 95 different stages of appendicitis and normal appendix in 5 cases: acute focal (n=10)...
Kafkas Journal of Medical Sciences
Aim: We aimed to investigate the efficacy and tolerability of modified FOLFIRI-Bevacizumab (mFOLF... more Aim: We aimed to investigate the efficacy and tolerability of modified FOLFIRI-Bevacizumab (mFOLFIRI-B) regime in the secondline treatment of metastatic colorectal cancer (mCRC) patients who received oxaliplatin-based regimen in the first-line treatment. Material and Method: The patients treated with mFOLFIRI-B regimen in second-line therapy who had progressed after oxaliplatin-based chemotherapy were included in this study. The datas of toxicity and efficacy of the regimen were retrospectively evaluated. Results: Total 172 mCRC patients had received mFOLFIRI-B regime in the second-line treatment. 39.5% objective response rate, 9.0 months (7.6 to 10.3) median progression-free survival, 19.0 months (15.1 to 26.2) median overall survival were found. Grade 3/4 toxicity was observed in 33.7%. Grade 3/4 hematologic toxicity was most frequently observed toxicity (31.9%). Conclusion: mFOLFIRI-B is an efficient and safe regimen for the second-line treatment of mCRC patients after the oxaliplatinbased regimen.
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2016
The incidence of all malignant tumours during pregnancy is extremely rare and esophageal carcinom... more The incidence of all malignant tumours during pregnancy is extremely rare and esophageal carcinoma ranges from 0.07 to 0.1% of all malignant neoplasms. The physiological changes during pregnancy frequently mask the complaints and symptoms related to the disease. The physical and physiological clinical conditions limit the diagnostic approaches. Therefore, the stage of cancer at the time of diagnosis is usually advanced. The management with cancer surgery and chemotherapy regimens must be modified in pregnant women in order to minimize fetal and maternal risks. Here, we report a very rare case of metastatic esophagus cancer in a 39-year-old woman with 28 weeks of pregnancy and aim to show the ultrasound (USG) and magnetic resonance imaging (MRI) findings with treatment and follow up management.
Case Reports in Obstetrics and Gynecology, 2015
Introduction. Vulvar cyst in adolescent girls is very uncommon. Epidermoid cyst can be seen in ma... more Introduction. Vulvar cyst in adolescent girls is very uncommon. Epidermoid cyst can be seen in many sites including face, trunk, and extremities but its occurrence in vulva is uncommon. This is the first case of epidermoid cyst of vulva reported in an adolescent girl.Case. A 17-year-old, adolescent girl admitted to our gynecology outpatient clinic with a complaint of painful and palpable mass in her vulva. On examination, a giant mass located in left vulva and labia majora with 11 cm in diameter was seen. The magnetic resonance imaging (MRI) showed a well-defined cystic mass without contrast enhancement. The surgery was advised to the patient and the pathologic examination of mass revealed vulvar epidermoid cyst.Discussion. Vulvar cysts generally grow slowly and the main etiologies are vulvar trauma and surgical interventions including episiotomy and female circumcision in some culture. The exact treatment is total surgical excision and pathologic examination. MRI is an important im...
Zhonghua yi xue za zhi, Jan 21, 2010
To investigate the value of magnetic resonance diffusion weighted imaging (DWI) in the differenti... more To investigate the value of magnetic resonance diffusion weighted imaging (DWI) in the differential diagnoses of malignant and benign thyroid lesions. Using echo planner imaging sequence with b value of 0, 100, 200, 300 and 400 s/mm(2) respectively, DWI was performed in 60 patients of focal thyroid lesions. The diagnosis was confirmed by pathological examination (benign, n = 30; malignant, n = 30). Apparent diffusion coefficient (ADC) values were measured. The differences were analyzed between two groups. With b value of 0, 100, 200, 300 and 400 s/mm(2) respectively, there were statistical differences in ADC values between benign and malignant lesions. The ADC value of malignant lesions was smaller than that of benign lesions (P < 0.05). Among different b values, 400 s/mm(2) was the most optimal one to diagnose thyroid nodular lesions. DWI with a b value of 400 s/mm(2) had a proper signal-to-noise ratio (SNO). And ADC value could be measured correctly. With a b value of 400 s/mm(...
Case reports in medicine, 2010
Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is an extremely rare complica... more Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is an extremely rare complication of infectious diseases. A rare case of brucellosis complicated by syndrome of inappropriate secretion of antidiuretic hormone (SIADH) cholestasis and pericardial involvement is reported. A 27-year-old woman was admitted for fever, abdominal pain, and scleral icterus. Her medical history revealed no recent use of diuretic agents. In addition to cholestasis and elevated liver enzymes, euvolemic hyponatremia, hypouricemia, low plasma osmolality, and high urinary osmolality were also detected. Surrenal and thyroid tests were also within normal range. Echocardiography revealed minimal pericardial effusion with normal cardiac functions. The final diagnosis was SIADH due to Brucellosis. Hyponatremia, cholestasis, and pericardial disease were resolved with effective antibrucellar treatment with streptomycine and doxycycline. After completing treatment of brucellosis, there was not any more ...
Case Reports in Infectious Diseases, 2015
Thyroid gland infection, although rare, may be a life threatening disease. Thyroid abscess, arisi... more Thyroid gland infection, although rare, may be a life threatening disease. Thyroid abscess, arising from acute suppurative thyroiditis (AST), is a rare clinic condition depending on widespread use of antibiotics. Infection may involve one or both lobes and abscess formation may not be apparent until late stage of the progress of illness. Thyroid left lobe is more often affected than the right one. Brucellosis, especially obvious in endemic areas, is a widely seen zoonosis around the world. Although brucella infection can affect many organs through various complications, thyroid gland infection is rare. We aimed to present ultrasonography (USG) and magnetic resonance images (MRI) of a case with an acute thyroiditis which rapidly developed and grew fast on the left half of the neck during the first postpartum month. As far as we know from literature reviewing, our case is the first case report of a thyroid abscess arising from brucella infection which is developed in first postpartum ...
Case Reports in Medicine, 2010
Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is an extremely rare complica... more Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is an extremely rare complication of infectious diseases. A rare case of brucellosis complicated by syndrome of inappropriate secretion of antidiuretic hormone (SIADH) cholestasis and pericardial involvement is reported. A 27-year-old woman was admitted for fever, abdominal pain, and scleral icterus. Her medical history revealed no recent use of diuretic agents. In addition to cholestasis and elevated liver enzymes, euvolemic hyponatremia, hypouricemia, low plasma osmolality, and high urinary osmolality were also detected. Surrenal and thyroid tests were also within normal range. Echocardiography revealed minimal pericardial effusion with normal cardiac functions. The final diagnosis was SIADH due to Brucellosis. Hyponatremia, cholestasis, and pericardial disease were resolved with effective antibrucellar treatment with streptomycine and doxycycline. After completing treatment of brucellosis, there was not any more ...
Journal of Clinical Imaging Science, 2014
Ectopic neurohypophysis is a pituitary gland abnormality, which can accompany growth hormone defi... more Ectopic neurohypophysis is a pituitary gland abnormality, which can accompany growth hormone deficiency associated with dwarfism. Here we present magnetic resonance imaging (MRI) findings of a rare case of ectopic neurohypophysis, corpus callosum dysgenesis, and periventricular neuronal heterotopia coexisting, with a review of the literature.