Anila Jaleel | Ziauddin Medical University (original) (raw)

Papers by Anila Jaleel

Research paper thumbnail of A Systematic Review on the Mental Health Status of Patients Infected With Monkeypox Virus

Soa. ceongso'nyeon jeongsin yihag, Apr 1, 2024

This study aims to extract and summarize the literature on the mental health status of patients w... more This study aims to extract and summarize the literature on the mental health status of patients with monkeypox. Methods: This review was carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines using different databases and publishers such as Scopus, Sage, ScienceDirect, PubMed, BMJ, Wiley Online Library, Wolters Kluwer OVID-SP, and Google Scholar. The literature review was based on monkeypox and mental health. The year of publication was 2021-2023, during the monkeypox disease period. Data were extracted from opinions, editorials, empirical studies, and surveys. Results: Based on the literature related to the mental status of patients with monkeypox, the following themes and subthemes were identified: anxiety and depression, self-harm and suicidal tendencies, neuropsychiatric symptoms, mental health, social stigma, sex workers, vaccination, and stress-related diseases. Conclusion: A review of monkeypox virus infection studies reveals that 25%-50% of patients experience anxiety and depression due to isolation, boredom, and loneliness. Factors such as infected people, a lack of competence among healthcare professionals, and shame over physical symptoms exacerbate mental insults. The implications of society include increased self-harm, suicide, low productivity, fear of stigmatization, and transmission of infection.

Research paper thumbnail of Thrombocytopenia in preeclampsia: an earlier detector of HELLP syndrome

PubMed, Sep 1, 1997

Platelet count was determined in eighty four pregnant women by direct visual method. Among them t... more Platelet count was determined in eighty four pregnant women by direct visual method. Among them thirty normal pregnant women were taken as control. Twenty-seven were preeclamptic and twenty seven eclamptic women. There was significant (P < 0.01) reduction in platelet count of preeclamptic and highly significant (P < 0.001) in eclamptic women as compared to controls. It is concluded that there is need to do platelet count in all pregnancy induced hypertensive women, which can be an earlier detector for HELLP syndrome.

Research paper thumbnail of Correlation of Radiological Findings (High Resolution Computed Tomography Chest) with Anti-SARS-COV-2 Antibodies in Patients Visiting Tertiary Care Hospitals

Annals of King Edward Medical University, Nov 25, 2022

Correlation of Radiological Findings (High Resolution Computed Tomography Chest) with Anti-SARS-C... more Correlation of Radiological Findings (High Resolution Computed Tomography Chest) with Anti-SARS-COV-2 Antibodies in Patients Visiting Tertiary Care Hospitals T he second wave of COVID 19 has surfaced worldwide in developed as well as developing countries. The data shows that in Pakistan the severity has increased, 2665 new cases and 59 deaths have been reported in 1 Pakistan as of November 22, 2020. Positive infectivity rate in Pakistan is 7.46% (Official website, Government of Pakistan, 2020). The confirmed diagnoses of COVID 19 depend on molecular testing i.e. polymerase chain reaction (PCR of RNA virus). The limited infrastructure created a backlog of testing in developing countries. Peeling et al, 2020 suggested that the Rapid antibody testing of good performing characteristics Introduction: may supplement in screening COVID 19 patients and prevent unnecessary isolation of false positive individ-2-4 uals due to cross reactivity with seasonal flu. Seroconversion period time after the infection of SARS-CoV-2and formation of IgM and IgG are varied in studies. Studies have stated that the formation of antibodies IgG and IgM after infection with virus were noticed at an early stage after the onset of symptom in some patients, and at intermediate stage or lately in others. The time period of formation of IgM was shor-5,6 ter than IgG. Some studies found that the median seroconversion period was between 10 to 12 days for IgM 7,8 and 12 to 14 days for IgG. However, another study

Research paper thumbnail of katG Gene association with Isoniazid Resistance in Multiple Drug Resistant Tuberculosis: Kat G gene and Tuberculosis

Mycobacterium Tuberculosis (MTB), the causative bacterial agent of tuberculosis, is the cause of ... more Mycobacterium Tuberculosis (MTB), the causative bacterial agent of tuberculosis, is the cause of health issues for about 10 million populations every year and is one of the leading causes of human deaths across the world. The prevalence of tuberculosis in Pakistan is reported to be 270/100,000 population 1. Pakistan is graded 5 th among 22 countries of the Eastern-Mediterranean territory. Prevalence of TB Multi drug-resistant (MDR) tuberculosis has emerged as a tenaciousperil, with 490,000 million cases registered in 2016 and around 110,000 cases that were sensitive to the anti-tuberculosis drug isoniazid but resistant to rifampicin, which is the most efficacious1stline anti-tuberculosis therapy (ATT) available in current era. Death due to MTB is graded above HIV infection in 2016 surveys 2. Multiple factors are responsible for spread of tuberculosis. It is due to penurious social, economic and political circumstances, absence of primary health facilities in many areas, malnourishment,

Research paper thumbnail of Correlation of Vitamin D with Monocytes and Lymphocytes in Care Takers of Tuberculosis Patients

Pakistan Journal of Medical and Health Sciences, Sep 30, 2022

Background: Close relatives of tuberculosis patients may be at increased risk of developing the d... more Background: Close relatives of tuberculosis patients may be at increased risk of developing the disease as they are in close contact with them Objectives: A cross-sectional research was conducted to determine correlation of Vitamin D with monocytes and lymphocytes in individuals with active tuberculosis as well as their care takers. Material and Methods: Total of 83 subjects was divided into three groups. Of the 83 participants, 31 had active tuberculosis, while 31 were adult family members who lived with and looked after the patients. 21 healthy age matched individuals were chosen to form the control group. SWISS Max analyzer was used to evaluate the levels of lymphocytes and monocytes in the blood and Vitamin D was measured by ELISA. Results: Vitamin D levels and monocyte lymphocyte count in the three groups showed substantial variation. The patient's monocyte and lymphocyte count showed a statistically significant correlation. However there was non-significant correlation of vitamin D with both monocyte and lymphocyte. Conclusion: Caretakers of active tuberculosis patients showed increased levels of circulating monocytes, lymphocytes as well as lower vitamin D levels with increased risk of developing tuberculosis.

Research paper thumbnail of Navigating Medical Education in the COVID-19 Era: Comparative Evaluation of Undergraduate Medical Curriculum Online vs. Hybrid Model

Background The evaluation of undergraduate medical curricula plays a crucial role in ensuring eff... more Background The evaluation of undergraduate medical curricula plays a crucial role in ensuring effectiveness and helps in continuous improvement. This study aimed to compare the context, input, process, and output of the first-year MBBS curriculum in the COVID-19 era (2019–20) and during the para-COVID-19 pandemic (2020–21) using online and hybrid teaching models. Methods A mixed-method study was conducted at Shalamar Medical and Dental College, Lahore, from April 2022 to April 2023. A committee consisting of medical educationists, administrators, and the first-year chairperson analyzed the curriculum. A questionnaire survey was administered, and focus group discussions (FGDs) were conducted with first-year students from the 2019–2020 and 2020–2021 batches, which were recorded. Various educational resources, including recorded lectures, guidebooks, planners, and question papers, were also analyzed. Additionally, admission merit, module assessments, and professional examination result...

Research paper thumbnail of Correlation of Vitamin D with Monocytes and Lymphocytes in Care Takers of Tuberculosis Patients

Pakistan Journal of Medical and Health Sciences

Background: Close relatives of tuberculosis patients may be at increased risk of developing the d... more Background: Close relatives of tuberculosis patients may be at increased risk of developing the disease as they are in close contact with them Objectives: A cross-sectional research was conducted to determine correlation of Vitamin D with monocytes and lymphocytes in individuals with active tuberculosis as well as their care takers. Material and Methods: Total of 83 subjects was divided into three groups. Of the 83 participants, 31 had active tuberculosis, while 31 were adult family members who lived with and looked after the patients. 21 healthy age matched individuals were chosen to form the control group. SWISS Max analyzer was used to evaluate the levels of lymphocytes and monocytes in the blood and Vitamin D was measured by ELISA. Results: Vitamin D levels and monocyte lymphocyte count in the three groups showed substantial variation. The patient's monocyte and lymphocyte count showed a statistically significant correlation. However there was non-significant correlation of ...

Research paper thumbnail of Correlation of Radiological Findings (High Resolution Computed Tomography Chest) with Anti-SARS-COV-2 Antibodies in Patients Visiting Tertiary Care Hospitals

Annals of King Edward Medical University

Background: Coronavirus (COVID 19) pandemic has taken so many lives and has contributed to an inc... more Background: Coronavirus (COVID 19) pandemic has taken so many lives and has contributed to an increase in morbidity due to its complications. The research is still in infancy and much has yet to be investigated. Objective: To correlate the HRCT findings on chest with antibody testing in patients visiting tertiary care hospitals in Lahore. Methodology: Three hundred and thirty-two patients with mild, moderate and severe symptoms of COVID 19 were recruited. Those with raised CRP levels were sent for HRCT chest and PCR testing as protocol of the hospitals. All patients were tested with Rapid antibody kits for reactivity. Results: Showed that males were affected more than females. Similarly, non-health care workers were more affected. All patients with bilateral involvement of lungs on HRCT chest and positive PCR findings also tested reactive on antibody testing. However, a few people with bilateral lung involvement and negative on PCR testing got reactive results on Rapid antibody test...

Research paper thumbnail of Impact of Online Teaching during COVID-19 Pandemic on Outcome of Medical students in Pakistan

Pakistan journal of medicine and dentistry, Jul 14, 2021

Research paper thumbnail of Association of Various Biomarkers and Liver Enzymes with Severity of COVID-19

Pakistan journal of medicine and dentistry, Jul 14, 2021

Research paper thumbnail of katG Gene association with Isoniazid Resistance in Multiple Drug Resistant Tuberculosis

Background: TB has been announced as a global emergency of this millennium. It is one of the lead... more Background: TB has been announced as a global emergency of this millennium. It is one of the leading causes of death among adults due to a single infectious agent. Pakistan is fifth among the twenty two Eastern Mediterranean Region countries with the highest burden of disease which is approximately 270 per 100,000. The emergence of drug resistant MTB poses a serious threat to the ongoing efforts to control the disease epidemic. Drug resistance to the first line drugs such as Isoniazid (INH) and Rifampicin (RIF) needs to be investigated. In this respect the role of various genes conferring resistance should be studied to find better treatment alternatives. The current practice of drug sensitivity testing requiring approximately three weeks is time consuming and a major cause of treatment delay. Objectives: The aim of the present study was to sequence the mutations in katG gene which contribute towards INH resistance and to study association of katG gene with INH resistance in MTB. Me...

Research paper thumbnail of Comparative Study on Effect of Condense Tannins of Supari and Neem Extract on the Liver Function of Rats

Aim: To see the effect of condense tannins of neem extract and supari extract on, the rats and to... more Aim: To see the effect of condense tannins of neem extract and supari extract on, the rats and to investigate the effect of condense tannins of supari and neem extract on the liver of rats. Results shows that condense tannins damage the liver of rats. The serum level of AST, ALP, ALT rises and as well as total protein level decreases.

Research paper thumbnail of Has the inclusion of a longitudinally integrated communication skills program improved consultation skills in medical students? A pilot study

Journal of Family Medicine and Primary Care, 2016

Background: Evidence highlights a lack of communication skills in doctors leading to dysfunctiona... more Background: Evidence highlights a lack of communication skills in doctors leading to dysfunctional consultations. To address this deficit, a private medical college instituted curricular reforms with inclusion of a longitudinal communication skills program. A pilot study was undertaken to evaluate the effectiveness of this program by comparing the consultation skills of medical students of this college with a medical college without a communication skills program. Methods: A 4-station Objective Structured Clinical Examination (OSCE) was conducted in the third and final year. Mann-Whitney U-test was used to compare the difference in the distribution between OSCE stations total and construct scores. Results: At the end of the third year, 21 (31.34%), students of the study site (medical college 1 [college with integrated longitudinal communication skills program]) and 31 (46.26%) students from the comparison site (medical college 2 [comparable college without communication skills program]) consented. Medical college 1 achieved a significantly higher overall mean total station score of 68.0% (standard deviation [SD] =13.5) versus 57.2% (SD = 15.4) (P < 0.001). Significantly higher mean scores were achieved on three stations. At the end of the final year, 19 students (29.3%) from medical college 1 and 22 (34%) students from medical college 2 consented. The difference in overall mean total station score reduced from 9.2% to 7.1% (70.2) (SD = 13.7) versus 63.1 (SD = 15.2) (P = 0.004). The mean scores of both colleges decreased in "Patient presenting with Hepatitis C Report" station (P values 0.004 and 0.775) and in "Patient Request for Faith Healing Therapy in Diabetes Mellitus" station (P values 0.0046 and 0.036), respectively. Conclusion: Longitudinal communication skills in an undergraduate curriculum positively impacted consultation skills. Community-based training and faculty development are required to develop effective patient-centered consultation skills.

Research paper thumbnail of Classification and criteria for diagnosis of diabetes mellitus: recent proposal

JPMA. The Journal of the Pakistan Medical Association, 1999

Research paper thumbnail of Stress level in medical students

Research paper thumbnail of Does Vitamin D Deficiency Contribute to the Severity of Asthma in Children and Adults?

Journal of Ayub Medical College, Abbottabad : JAMC

Role of vitamin D in the health of bones has been well established for over decades; It was known... more Role of vitamin D in the health of bones has been well established for over decades; It was known that its deficiency caused rickets in children and osteomalacia in adults. Later it was discovered that these can be corrected by giving vitamin D. Researchers discovered that vitamin D can be synthesized by exposure to sun. Hence it was also named "the sunshine vitamin". As time passed it was observed that low levels of vitamin D were associated with multiple diseases. This sparked the interest of the scientific community to further the research on vitamin D which led to the studies that started associating vitamin D with various diseases like cancers (prostate, colon and breast), autoimmune diseases (rheumatoid arthritis), infectious diseases (tuberculosis, hepatitis B, hepatitis C, HIV), cardiovascular diseases, mental illnesses (schizophrenia), diabetes mellitus (type 1, type 2 and gestational) and allergic conditions like asthma. With time, more studies were carried out r...

Research paper thumbnail of Circulating Levels of Adipokines and TNF in Patients with and without Type 1 Diabetes

Journal of the Dow University of Health Sciences, 2013

Objective: The aim of this study was to evaluate circulating levels of adiponectin, resistin, vis... more Objective: The aim of this study was to evaluate circulating levels of adiponectin, resistin, visfatin and TNFin type1 diabetic children and young adolescents.Patients and Methods:Design: Cross-sectional studySetting: Ziauddin University KarachiSubjects: 90 subjects (30 type I diabetic (T1DM) subjects and 60 non-diabetic controls) between the age of05-15 years.Methods: Serum adiponectin, resistin, visfatin, TNF and insulin were measured using ELISA and fastingblood sugar by glucose oxidase (Standard Kit method).Results: Out of 90 study subjects, 30 were type 1 diabetic patients and 60 non-diabetic controls. Increased levelsof serum adiponectin levels were significant in type I diabetic subjects (TIDM) (10.83+1.73) compared withcontrols (9.07+1.25). Same pattern was observed for serum TNF in diabetic subjects (10.82+4.53) comparedwith controls (7.22+ 2.22). Significantly increased serum visfatin levels were found in TIDM patients (10.89+2.72)compared with controls (4.97+1.57). Signif...

Research paper thumbnail of Ageing and health: free radicals and oxidative stress

Journal of the College of Physicians and Surgeons, 2008

Research paper thumbnail of Discriminant Validity and Reliability of Scores of Multiple Choice and Short Essay Questions

Research paper thumbnail of Perception of Medical Students on Structured Viva Examination in an Integrated Undergraduate Curriculum at Ziauddin University

Journal of the Dow University of Health Sciences, 2010

Introduction: Exponential growth ofknowledge in the biomedical field has forced the medical educa... more Introduction: Exponential growth ofknowledge in the biomedical field has forced the medical educators for a change from traditional to integrated curriculum and conventional assessment techniques to newer structured techniques. Objective: Survey of medical students' views about the Structured Viva Examination (SVE) in an integrated curriculum. Methods: Feedback forms of Structured Viva Examination (SVE) were given to 144 students o f first and second year MBBS (2008), after they completed their professional examination. SVE feedback form was c a te g o riz e d in the dom ains o f agree, disag ree and n e u tra l w ith five d iffe re n t statem ents. Results: Out o f 144 students 140 responded. One hundred and thirteen out ofhundred and forty (80.71%) students agreed that the language o f the cases was simple and easy to understand. One hundred and ten (78.57%) stated that the reading time of cases was adequate. One hundred and seven (76.42%) agreed that the time was adequately s...

Research paper thumbnail of A Systematic Review on the Mental Health Status of Patients Infected With Monkeypox Virus

Soa. ceongso'nyeon jeongsin yihag, Apr 1, 2024

This study aims to extract and summarize the literature on the mental health status of patients w... more This study aims to extract and summarize the literature on the mental health status of patients with monkeypox. Methods: This review was carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines using different databases and publishers such as Scopus, Sage, ScienceDirect, PubMed, BMJ, Wiley Online Library, Wolters Kluwer OVID-SP, and Google Scholar. The literature review was based on monkeypox and mental health. The year of publication was 2021-2023, during the monkeypox disease period. Data were extracted from opinions, editorials, empirical studies, and surveys. Results: Based on the literature related to the mental status of patients with monkeypox, the following themes and subthemes were identified: anxiety and depression, self-harm and suicidal tendencies, neuropsychiatric symptoms, mental health, social stigma, sex workers, vaccination, and stress-related diseases. Conclusion: A review of monkeypox virus infection studies reveals that 25%-50% of patients experience anxiety and depression due to isolation, boredom, and loneliness. Factors such as infected people, a lack of competence among healthcare professionals, and shame over physical symptoms exacerbate mental insults. The implications of society include increased self-harm, suicide, low productivity, fear of stigmatization, and transmission of infection.

Research paper thumbnail of Thrombocytopenia in preeclampsia: an earlier detector of HELLP syndrome

PubMed, Sep 1, 1997

Platelet count was determined in eighty four pregnant women by direct visual method. Among them t... more Platelet count was determined in eighty four pregnant women by direct visual method. Among them thirty normal pregnant women were taken as control. Twenty-seven were preeclamptic and twenty seven eclamptic women. There was significant (P < 0.01) reduction in platelet count of preeclamptic and highly significant (P < 0.001) in eclamptic women as compared to controls. It is concluded that there is need to do platelet count in all pregnancy induced hypertensive women, which can be an earlier detector for HELLP syndrome.

Research paper thumbnail of Correlation of Radiological Findings (High Resolution Computed Tomography Chest) with Anti-SARS-COV-2 Antibodies in Patients Visiting Tertiary Care Hospitals

Annals of King Edward Medical University, Nov 25, 2022

Correlation of Radiological Findings (High Resolution Computed Tomography Chest) with Anti-SARS-C... more Correlation of Radiological Findings (High Resolution Computed Tomography Chest) with Anti-SARS-COV-2 Antibodies in Patients Visiting Tertiary Care Hospitals T he second wave of COVID 19 has surfaced worldwide in developed as well as developing countries. The data shows that in Pakistan the severity has increased, 2665 new cases and 59 deaths have been reported in 1 Pakistan as of November 22, 2020. Positive infectivity rate in Pakistan is 7.46% (Official website, Government of Pakistan, 2020). The confirmed diagnoses of COVID 19 depend on molecular testing i.e. polymerase chain reaction (PCR of RNA virus). The limited infrastructure created a backlog of testing in developing countries. Peeling et al, 2020 suggested that the Rapid antibody testing of good performing characteristics Introduction: may supplement in screening COVID 19 patients and prevent unnecessary isolation of false positive individ-2-4 uals due to cross reactivity with seasonal flu. Seroconversion period time after the infection of SARS-CoV-2and formation of IgM and IgG are varied in studies. Studies have stated that the formation of antibodies IgG and IgM after infection with virus were noticed at an early stage after the onset of symptom in some patients, and at intermediate stage or lately in others. The time period of formation of IgM was shor-5,6 ter than IgG. Some studies found that the median seroconversion period was between 10 to 12 days for IgM 7,8 and 12 to 14 days for IgG. However, another study

Research paper thumbnail of katG Gene association with Isoniazid Resistance in Multiple Drug Resistant Tuberculosis: Kat G gene and Tuberculosis

Mycobacterium Tuberculosis (MTB), the causative bacterial agent of tuberculosis, is the cause of ... more Mycobacterium Tuberculosis (MTB), the causative bacterial agent of tuberculosis, is the cause of health issues for about 10 million populations every year and is one of the leading causes of human deaths across the world. The prevalence of tuberculosis in Pakistan is reported to be 270/100,000 population 1. Pakistan is graded 5 th among 22 countries of the Eastern-Mediterranean territory. Prevalence of TB Multi drug-resistant (MDR) tuberculosis has emerged as a tenaciousperil, with 490,000 million cases registered in 2016 and around 110,000 cases that were sensitive to the anti-tuberculosis drug isoniazid but resistant to rifampicin, which is the most efficacious1stline anti-tuberculosis therapy (ATT) available in current era. Death due to MTB is graded above HIV infection in 2016 surveys 2. Multiple factors are responsible for spread of tuberculosis. It is due to penurious social, economic and political circumstances, absence of primary health facilities in many areas, malnourishment,

Research paper thumbnail of Correlation of Vitamin D with Monocytes and Lymphocytes in Care Takers of Tuberculosis Patients

Pakistan Journal of Medical and Health Sciences, Sep 30, 2022

Background: Close relatives of tuberculosis patients may be at increased risk of developing the d... more Background: Close relatives of tuberculosis patients may be at increased risk of developing the disease as they are in close contact with them Objectives: A cross-sectional research was conducted to determine correlation of Vitamin D with monocytes and lymphocytes in individuals with active tuberculosis as well as their care takers. Material and Methods: Total of 83 subjects was divided into three groups. Of the 83 participants, 31 had active tuberculosis, while 31 were adult family members who lived with and looked after the patients. 21 healthy age matched individuals were chosen to form the control group. SWISS Max analyzer was used to evaluate the levels of lymphocytes and monocytes in the blood and Vitamin D was measured by ELISA. Results: Vitamin D levels and monocyte lymphocyte count in the three groups showed substantial variation. The patient's monocyte and lymphocyte count showed a statistically significant correlation. However there was non-significant correlation of vitamin D with both monocyte and lymphocyte. Conclusion: Caretakers of active tuberculosis patients showed increased levels of circulating monocytes, lymphocytes as well as lower vitamin D levels with increased risk of developing tuberculosis.

Research paper thumbnail of Navigating Medical Education in the COVID-19 Era: Comparative Evaluation of Undergraduate Medical Curriculum Online vs. Hybrid Model

Background The evaluation of undergraduate medical curricula plays a crucial role in ensuring eff... more Background The evaluation of undergraduate medical curricula plays a crucial role in ensuring effectiveness and helps in continuous improvement. This study aimed to compare the context, input, process, and output of the first-year MBBS curriculum in the COVID-19 era (2019–20) and during the para-COVID-19 pandemic (2020–21) using online and hybrid teaching models. Methods A mixed-method study was conducted at Shalamar Medical and Dental College, Lahore, from April 2022 to April 2023. A committee consisting of medical educationists, administrators, and the first-year chairperson analyzed the curriculum. A questionnaire survey was administered, and focus group discussions (FGDs) were conducted with first-year students from the 2019–2020 and 2020–2021 batches, which were recorded. Various educational resources, including recorded lectures, guidebooks, planners, and question papers, were also analyzed. Additionally, admission merit, module assessments, and professional examination result...

Research paper thumbnail of Correlation of Vitamin D with Monocytes and Lymphocytes in Care Takers of Tuberculosis Patients

Pakistan Journal of Medical and Health Sciences

Background: Close relatives of tuberculosis patients may be at increased risk of developing the d... more Background: Close relatives of tuberculosis patients may be at increased risk of developing the disease as they are in close contact with them Objectives: A cross-sectional research was conducted to determine correlation of Vitamin D with monocytes and lymphocytes in individuals with active tuberculosis as well as their care takers. Material and Methods: Total of 83 subjects was divided into three groups. Of the 83 participants, 31 had active tuberculosis, while 31 were adult family members who lived with and looked after the patients. 21 healthy age matched individuals were chosen to form the control group. SWISS Max analyzer was used to evaluate the levels of lymphocytes and monocytes in the blood and Vitamin D was measured by ELISA. Results: Vitamin D levels and monocyte lymphocyte count in the three groups showed substantial variation. The patient's monocyte and lymphocyte count showed a statistically significant correlation. However there was non-significant correlation of ...

Research paper thumbnail of Correlation of Radiological Findings (High Resolution Computed Tomography Chest) with Anti-SARS-COV-2 Antibodies in Patients Visiting Tertiary Care Hospitals

Annals of King Edward Medical University

Background: Coronavirus (COVID 19) pandemic has taken so many lives and has contributed to an inc... more Background: Coronavirus (COVID 19) pandemic has taken so many lives and has contributed to an increase in morbidity due to its complications. The research is still in infancy and much has yet to be investigated. Objective: To correlate the HRCT findings on chest with antibody testing in patients visiting tertiary care hospitals in Lahore. Methodology: Three hundred and thirty-two patients with mild, moderate and severe symptoms of COVID 19 were recruited. Those with raised CRP levels were sent for HRCT chest and PCR testing as protocol of the hospitals. All patients were tested with Rapid antibody kits for reactivity. Results: Showed that males were affected more than females. Similarly, non-health care workers were more affected. All patients with bilateral involvement of lungs on HRCT chest and positive PCR findings also tested reactive on antibody testing. However, a few people with bilateral lung involvement and negative on PCR testing got reactive results on Rapid antibody test...

Research paper thumbnail of Impact of Online Teaching during COVID-19 Pandemic on Outcome of Medical students in Pakistan

Pakistan journal of medicine and dentistry, Jul 14, 2021

Research paper thumbnail of Association of Various Biomarkers and Liver Enzymes with Severity of COVID-19

Pakistan journal of medicine and dentistry, Jul 14, 2021

Research paper thumbnail of katG Gene association with Isoniazid Resistance in Multiple Drug Resistant Tuberculosis

Background: TB has been announced as a global emergency of this millennium. It is one of the lead... more Background: TB has been announced as a global emergency of this millennium. It is one of the leading causes of death among adults due to a single infectious agent. Pakistan is fifth among the twenty two Eastern Mediterranean Region countries with the highest burden of disease which is approximately 270 per 100,000. The emergence of drug resistant MTB poses a serious threat to the ongoing efforts to control the disease epidemic. Drug resistance to the first line drugs such as Isoniazid (INH) and Rifampicin (RIF) needs to be investigated. In this respect the role of various genes conferring resistance should be studied to find better treatment alternatives. The current practice of drug sensitivity testing requiring approximately three weeks is time consuming and a major cause of treatment delay. Objectives: The aim of the present study was to sequence the mutations in katG gene which contribute towards INH resistance and to study association of katG gene with INH resistance in MTB. Me...

Research paper thumbnail of Comparative Study on Effect of Condense Tannins of Supari and Neem Extract on the Liver Function of Rats

Aim: To see the effect of condense tannins of neem extract and supari extract on, the rats and to... more Aim: To see the effect of condense tannins of neem extract and supari extract on, the rats and to investigate the effect of condense tannins of supari and neem extract on the liver of rats. Results shows that condense tannins damage the liver of rats. The serum level of AST, ALP, ALT rises and as well as total protein level decreases.

Research paper thumbnail of Has the inclusion of a longitudinally integrated communication skills program improved consultation skills in medical students? A pilot study

Journal of Family Medicine and Primary Care, 2016

Background: Evidence highlights a lack of communication skills in doctors leading to dysfunctiona... more Background: Evidence highlights a lack of communication skills in doctors leading to dysfunctional consultations. To address this deficit, a private medical college instituted curricular reforms with inclusion of a longitudinal communication skills program. A pilot study was undertaken to evaluate the effectiveness of this program by comparing the consultation skills of medical students of this college with a medical college without a communication skills program. Methods: A 4-station Objective Structured Clinical Examination (OSCE) was conducted in the third and final year. Mann-Whitney U-test was used to compare the difference in the distribution between OSCE stations total and construct scores. Results: At the end of the third year, 21 (31.34%), students of the study site (medical college 1 [college with integrated longitudinal communication skills program]) and 31 (46.26%) students from the comparison site (medical college 2 [comparable college without communication skills program]) consented. Medical college 1 achieved a significantly higher overall mean total station score of 68.0% (standard deviation [SD] =13.5) versus 57.2% (SD = 15.4) (P < 0.001). Significantly higher mean scores were achieved on three stations. At the end of the final year, 19 students (29.3%) from medical college 1 and 22 (34%) students from medical college 2 consented. The difference in overall mean total station score reduced from 9.2% to 7.1% (70.2) (SD = 13.7) versus 63.1 (SD = 15.2) (P = 0.004). The mean scores of both colleges decreased in "Patient presenting with Hepatitis C Report" station (P values 0.004 and 0.775) and in "Patient Request for Faith Healing Therapy in Diabetes Mellitus" station (P values 0.0046 and 0.036), respectively. Conclusion: Longitudinal communication skills in an undergraduate curriculum positively impacted consultation skills. Community-based training and faculty development are required to develop effective patient-centered consultation skills.

Research paper thumbnail of Classification and criteria for diagnosis of diabetes mellitus: recent proposal

JPMA. The Journal of the Pakistan Medical Association, 1999

Research paper thumbnail of Stress level in medical students

Research paper thumbnail of Does Vitamin D Deficiency Contribute to the Severity of Asthma in Children and Adults?

Journal of Ayub Medical College, Abbottabad : JAMC

Role of vitamin D in the health of bones has been well established for over decades; It was known... more Role of vitamin D in the health of bones has been well established for over decades; It was known that its deficiency caused rickets in children and osteomalacia in adults. Later it was discovered that these can be corrected by giving vitamin D. Researchers discovered that vitamin D can be synthesized by exposure to sun. Hence it was also named "the sunshine vitamin". As time passed it was observed that low levels of vitamin D were associated with multiple diseases. This sparked the interest of the scientific community to further the research on vitamin D which led to the studies that started associating vitamin D with various diseases like cancers (prostate, colon and breast), autoimmune diseases (rheumatoid arthritis), infectious diseases (tuberculosis, hepatitis B, hepatitis C, HIV), cardiovascular diseases, mental illnesses (schizophrenia), diabetes mellitus (type 1, type 2 and gestational) and allergic conditions like asthma. With time, more studies were carried out r...

Research paper thumbnail of Circulating Levels of Adipokines and TNF in Patients with and without Type 1 Diabetes

Journal of the Dow University of Health Sciences, 2013

Objective: The aim of this study was to evaluate circulating levels of adiponectin, resistin, vis... more Objective: The aim of this study was to evaluate circulating levels of adiponectin, resistin, visfatin and TNFin type1 diabetic children and young adolescents.Patients and Methods:Design: Cross-sectional studySetting: Ziauddin University KarachiSubjects: 90 subjects (30 type I diabetic (T1DM) subjects and 60 non-diabetic controls) between the age of05-15 years.Methods: Serum adiponectin, resistin, visfatin, TNF and insulin were measured using ELISA and fastingblood sugar by glucose oxidase (Standard Kit method).Results: Out of 90 study subjects, 30 were type 1 diabetic patients and 60 non-diabetic controls. Increased levelsof serum adiponectin levels were significant in type I diabetic subjects (TIDM) (10.83+1.73) compared withcontrols (9.07+1.25). Same pattern was observed for serum TNF in diabetic subjects (10.82+4.53) comparedwith controls (7.22+ 2.22). Significantly increased serum visfatin levels were found in TIDM patients (10.89+2.72)compared with controls (4.97+1.57). Signif...

Research paper thumbnail of Ageing and health: free radicals and oxidative stress

Journal of the College of Physicians and Surgeons, 2008

Research paper thumbnail of Discriminant Validity and Reliability of Scores of Multiple Choice and Short Essay Questions

Research paper thumbnail of Perception of Medical Students on Structured Viva Examination in an Integrated Undergraduate Curriculum at Ziauddin University

Journal of the Dow University of Health Sciences, 2010

Introduction: Exponential growth ofknowledge in the biomedical field has forced the medical educa... more Introduction: Exponential growth ofknowledge in the biomedical field has forced the medical educators for a change from traditional to integrated curriculum and conventional assessment techniques to newer structured techniques. Objective: Survey of medical students' views about the Structured Viva Examination (SVE) in an integrated curriculum. Methods: Feedback forms of Structured Viva Examination (SVE) were given to 144 students o f first and second year MBBS (2008), after they completed their professional examination. SVE feedback form was c a te g o riz e d in the dom ains o f agree, disag ree and n e u tra l w ith five d iffe re n t statem ents. Results: Out o f 144 students 140 responded. One hundred and thirteen out ofhundred and forty (80.71%) students agreed that the language o f the cases was simple and easy to understand. One hundred and ten (78.57%) stated that the reading time of cases was adequate. One hundred and seven (76.42%) agreed that the time was adequately s...