DSS (original) (raw)

This is the released version of DSS; for the devel version, seeDSS.

Dispersion shrinkage for sequencing data

Bioconductor version: Release (3.20)

DSS is an R library performing differntial analysis for count-based sequencing data. It detectes differentially expressed genes (DEGs) from RNA-seq, and differentially methylated loci or regions (DML/DMRs) from bisulfite sequencing (BS-seq). The core of DSS is a new dispersion shrinkage method for estimating the dispersion parameter from Gamma-Poisson or Beta-Binomial distributions.

Author: Hao Wu<hao.wu at emory.edu>, Hao Feng

Maintainer: Hao Wu <hao.wu at emory.edu>, Hao Feng

Citation (from within R, enter citation("DSS")):

Installation

To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DSS")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DSS")

Details

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Follow Installation instructions to use this package in your R session.