GRSxE: Testing Gene-Environment Interactions Through Genetic Risk Scores (original) (raw)
Statistical testing procedures for detecting GxE (gene-environment) interactions. The main focus lies on GRSxE interaction tests that aim at detecting GxE interactions through GRS (genetic risk scores). Moreover, a novel testing procedure based on bagging and OOB (out-of-bag) predictions is implemented for incorporating all available observations at both GRS construction and GxE testing (Lau et al., 2023, <doi:10.1038/s41598-023-28172-4>).
Version: | 1.0.1 |
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Imports: | glmnet, ranger, stats, utils |
Published: | 2023-10-30 |
DOI: | 10.32614/CRAN.package.GRSxE |
Author: | Michael Lau [aut, cre] |
Maintainer: | Michael Lau <michael.lau at hhu.de> |
License: | MIT + file |
NeedsCompilation: | no |
Materials: | README |
CRAN checks: | GRSxE results |
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