doi:10.1177/1740774520988244>. The Indifference-zone approach is based on Sobel and Huyett (1957) <doi:10.1002/j.1538-7305.1957.tb02411.x> and Bechhofer, Santner, and Goldsman (1995, ISBN:978-0-471-57427-9).">

ssutil: Sample Size Calculation Tools (original) (raw)

Functions for sample size estimation and simulation in clinical trials. Includes methods for selecting the best group using the Indifference-zone approach, as well as designs for non-inferiority, equivalence, and negative binomial models. For the sample size calculation for non-inferiority of vaccines, the approach is based on Fleming, Powers, and Huang (2021) <doi:10.1177/1740774520988244>. The Indifference-zone approach is based on Sobel and Huyett (1957) <doi:10.1002/j.1538-7305.1957.tb02411.x> and Bechhofer, Santner, and Goldsman (1995, ISBN:978-0-471-57427-9).

Version: 1.0.0
Depends: R (≥ 4.1)
Imports: stats, stringr, broom, MASS, gsDesign, mvtnorm, tibble
Suggests: knitr, rmarkdown, spelling, testthat (≥ 3.0.0)
Published: 2025-06-12
DOI: 10.32614/CRAN.package.ssutil
Author: John J. Aponte ORCID iD [aut, cre], Chris Gast [ctb]
Maintainer: John J. Aponte <john.j.aponte at gmail.com>
BugReports: https://github.com/johnaponte/ssutil/issues
License: AGPL (≥ 3)
URL: https://johnaponte.github.io/ssutil/,https://github.com/johnaponte/ssutil
NeedsCompilation: no
Language: en-US
Materials: README, NEWS
CRAN checks: ssutil results

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