Simple Method for the Esterification of Carboxylic Acids (original) (raw)

Bernhard Neises and Wolfgang Steglich*

*Institut f�r Organische Chemie und Biochemie der Universit�t, Gerhard-Domagk-Strasse 1, D-5300 Bonn (Germany)

B. Neises, W. Steglich, Angew. Chem. Int. Ed., 1978, 17, 522-524.

DOI: 10.1002/anie.197805221


Abstract

The addition of 3-10 mol-% DMAP accelerates the DCC-activated esterification of carboxylic acids with alcohols and thiols to such an extent that formation of side products is suppressed and even sterically demanding esters are formed in good yields at room temperature.

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Key Words

Steglich Esterification, esters,thioesters


ID: J06-Y1978-040