spatialGE: Visualization and Analysis of Spatial Heterogeneity in Spatially-Resolved Gene Expression (original) (raw)

Visualization and analysis of spatially resolved transcriptomics data. The 'spatialGE' R package provides methods for visualizing and analyzing spatially resolved transcriptomics data, such as 10X Visium, CosMx, or csv/tsv gene expression matrices. It includes tools for spatial interpolation, autocorrelation analysis, tissue domain detection, gene set enrichment, and differential expression analysis using spatial mixed models.

Version:

1.2.2

Imports:

arrow, BiocParallel, concaveman, ComplexHeatmap, data.table, DelayedArray, DelayedMatrixStats, dynamicTreeCut, dplyr, EBImage, ggforce, ggplot2, ggpolypath, ggrepel, gstat, GSVA, hdf5r, jpeg, jsonlite, khroma (≥ 1.6.0), magrittr, Matrix, MASS, methods, parallel, png, RColorBrewer, Rcpp (≥ 1.0.7), readr, readxl, rlang, scales, sctransform, sfsmisc, sf, sp, spaMM, spdep, stats, stringr, tibble, tidyr, utils, uwot, wordspace

LinkingTo:

Rcpp, RcppEigen, RcppProgress

Suggests:

curl, geoR, ggpubr, httr, janitor, kableExtra, knitr, msigdbr, progress, rmarkdown, rpart, R.utils, scSpatialSIM, spatstat, SeuratObject, tidyverse, testthat (≥ 3.0.0)

Published:

2025-06-04

DOI:

10.32614/CRAN.package.spatialGE

Author:

Oscar Ospina ORCID iD [aut, cre], Alex Soupir ORCID iD [aut], Brooke Fridley ORCID iD [aut], Satija Lab [cph] (Copyright holder of code fragments from Seurat function FindVariableFeatures)

Maintainer:

Oscar Ospina <oscar.ospina at jhmi.edu>

License:

MIT + file

Copyright:

ins/COPYRIGHT

NeedsCompilation:

yes

Materials:

README NEWS

CRAN checks:

spatialGE results