| dbo:abstract |
γ-Melanocyte-stimulating hormone (γ-MSH) is an endogenous peptide hormone and neuropeptide. It is a melanocortin, specifically, one of the three types of melanocyte-stimulating hormone (MSH), and is produced from proopiomelanocortin (POMC). It is an agonist of the MC1, MC3, MC4, and MC5 receptors. It exists in three forms, γ1-MSH, γ2-MSH, and γ3-MSH. Gamma-MSH regulated cardiovascular functions. Gama-MSH effects are measured through the effects it has on the central neural pathway dispersed throughout the kidney. It is not moderated based on tubular sodium transport. Gamma-MSH activates MC3R in renal tubular cells by limiting sodium absorption by inhibiting the central neural pathway.This regulates sodium balance and blood pressure. If MC3R is absent then there is resistance in γ-MSH which results in hypertension on HSD. (en) |
| dbo:alternativeName |
gamma-MSH, γ-melanotropin, γ-melanocortin, γ-intermedin (en) |
| dbo:iupacName |
L-Tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalaninamide (en) |
| dbo:wikiPageID |
46801915 (xsd:integer) |
| dbo:wikiPageLength |
3412 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1058134243 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Melanocortin dbr:Melanocortin_1_receptor dbr:Melanocortin_4_receptor dbr:Melanocortin_5_receptor dbr:Neuropeptide dbr:Proopiomelanocortin dbr:Melanocyte-stimulating_hormone dbr:Peptide_hormone dbr:Melanocortin_3_receptor dbr:Adrenocorticotropic_hormone dbr:Agonist dbc:Human_hormones dbr:Endogenous dbc:Peptide_hormones dbc:Melanocortin_receptor_agonists dbr:Α-Melanocyte-stimulating_hormone dbr:Β-Melanocyte-stimulating_hormone |
| dbp:iupacname |
L-Tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalaninamide (en) |
| dbp:othernames |
gamma-MSH, γ-melanotropin, γ-melanocortin, γ-intermedin (en) |
| dbp:wikiPageUsesTemplate |
dbt:Biochemistry-stub dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Hormones dbt:Reflist dbt:Melanocortin_receptor_modulators dbt:Neuropeptides |
| dct:subject |
dbc:Human_hormones dbc:Peptide_hormones dbc:Melanocortin_receptor_agonists |
| gold:hypernym |
dbr:Hormone |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 dbo:ChemicalCompound dbo:Protein |
| rdfs:comment |
γ-Melanocyte-stimulating hormone (γ-MSH) is an endogenous peptide hormone and neuropeptide. It is a melanocortin, specifically, one of the three types of melanocyte-stimulating hormone (MSH), and is produced from proopiomelanocortin (POMC). It is an agonist of the MC1, MC3, MC4, and MC5 receptors. It exists in three forms, γ1-MSH, γ2-MSH, and γ3-MSH. (en) |
| rdfs:label |
Gamma-Melanocyte-stimulating hormone (en) |
| owl:sameAs |
freebase:Gamma-Melanocyte-stimulating hormone yago-res:Gamma-Melanocyte-stimulating hormone wikidata:Gamma-Melanocyte-stimulating hormone https://global.dbpedia.org/id/xt48 |
| prov:wasDerivedFrom |
wikipedia-en:Gamma-Melanocyte-stimulating_hormone?oldid=1058134243&ns=0 |
| foaf:isPrimaryTopicOf |
wikipedia-en:Gamma-Melanocyte-stimulating_hormone |
| is dbo:wikiPageRedirects of |
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| is dbo:wikiPageWikiLink of |
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