3,4-Methylenedioxyphenethylamine (original) (raw)
3,4-Methylenedioxyphenethylamine, also known as 3,4-MDPEA, MDPEA, and homopiperonylamine, is a substituted phenethylamine formed by adding a methylenedioxy group to phenethylamine. It is structurally similar to MDA, but without the methyl group at the alpha position.
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| dbo:abstract | 3,4-Methylenedioxyphenethylamine, also known as 3,4-MDPEA, MDPEA, and homopiperonylamine, is a substituted phenethylamine formed by adding a methylenedioxy group to phenethylamine. It is structurally similar to MDA, but without the methyl group at the alpha position. According to Alexander Shulgin in his book PiHKAL, MDPEA appears to be biologically inactive. This is likely because of extensive first-pass metabolism by the enzyme monoamine oxidase. However, if MDPEA were either used in high enough of doses (e.g., 1-2 grams), or in combination with a monoamine oxidase inhibitor (MAOI), it is probable that it would become sufficiently active, though it would likely have a relatively short duration of action. This idea is similar in concept to the use of selective MAOA inhibitors and selective MAOB inhibitors in augmentation of dimethyltryptamine (DMT) and phenethylamine (PEA), respectively. (en) Le 3,4-méthylènedioxyphénéthylamine (MDPEA), également connu sous le nom homopipéronylamine, est une phénéthylamine substituée formée par l'addition d'un groupe méthylènedioxy sur la phénéthylamine. Il ressemble à la MDA, mais sans le groupe méthyle en position alpha. Selon Alexander Shulgin dans son livre PiHKAL, MDPEA semble être biologiquement inactif. Cela est probablement dû au premier passage hépatique et au métabolisme qui détruit la MDPEA par la monoamine oxydase (MAO). Toutefois, si MDPEA était pris à haute dose (par exemple, un ou deux grammes), ou en combinaison avec un inhibiteur de la monoamine oxydase (IMAO), il est probable qu'il deviendrait actif mais il aurait probablement une courte durée d'action. (fr) |
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| rdfs:comment | 3,4-Methylenedioxyphenethylamine, also known as 3,4-MDPEA, MDPEA, and homopiperonylamine, is a substituted phenethylamine formed by adding a methylenedioxy group to phenethylamine. It is structurally similar to MDA, but without the methyl group at the alpha position. (en) Le 3,4-méthylènedioxyphénéthylamine (MDPEA), également connu sous le nom homopipéronylamine, est une phénéthylamine substituée formée par l'addition d'un groupe méthylènedioxy sur la phénéthylamine. Il ressemble à la MDA, mais sans le groupe méthyle en position alpha. (fr) |
| rdfs:label | 3,4-Methylenedioxyphenethylamine (en) Méthylènedioxyphénéthylamine (fr) |
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