| dbo:abstract |
Lophophine (MMDPEA or 3-methoxy-4,5-methylenedioxyphenethylamine) is a putative psychedelic and entactogen drug of the methylenedioxyphenethylamine class. It is the α-demethylated homologue of MMDA, and is also closely related to mescaline. Alexander Shulgin originally suggested that lophophine may be a natural constituent of peyote (Lophophora williamsii) due to it being the only logical chemical intermediate for the biosynthesis of several tetrahydroisoquinolines known to be present in this cactus species. Subsequently, lophophine was indeed shown to be a minor component of both peyote and San Pedro cactus. Shulgin reports that lophophine is active in the dosage range of 150–250 mg. He states that at these doses, lophophine has some similarity to mescaline in action, in producing a peaceful elevation of mood, euphoria, and mild enhancement of visual perception, but without the generation of closed-eye mental imagery. Shulgin also notes that (in contrast to mescaline), lophophine causes no nausea. (en) 3-甲氧基-4,5-亚甲二氧基苯乙胺，简称MMDPEA是类的迷幻药和药物。它是的α-脱甲基化类似物，也和麦司卡林紧密相关。 亚历山大·舒尔金最初认为3-甲氧基-4,5-亚甲二氧基苯乙胺可能是乌羽玉（Lophophora williamsii）的天然成分，因为它是已知存在于这种仙人掌物种中的几种四氢异喹啉生物合成唯一合乎逻辑的中间体。随后，3-甲氧基-4,5-亚甲二氧基苯乙胺确实被证明是乌羽玉和的次要成分。 舒尔金报告说，3-甲氧基-4,5-亚甲二氧基苯乙胺在150至250毫克的剂量范围内具有活性。他指出，在这些剂量下，3-甲氧基-4,5-亚甲二氧基苯乙胺在作用上与麦司卡林有一些相似之处，产生平静的情绪提升、欣快感和视觉感知的轻度增强，但没有产生心像。舒尔金还指出（与麦司卡林相比），3-甲氧基-4,5-亚甲二氧基苯乙胺不会引起恶心。 (zh) |
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90239 |
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| rdfs:comment |
3-甲氧基-4,5-亚甲二氧基苯乙胺，简称MMDPEA是类的迷幻药和药物。它是的α-脱甲基化类似物，也和麦司卡林紧密相关。 亚历山大·舒尔金最初认为3-甲氧基-4,5-亚甲二氧基苯乙胺可能是乌羽玉（Lophophora williamsii）的天然成分，因为它是已知存在于这种仙人掌物种中的几种四氢异喹啉生物合成唯一合乎逻辑的中间体。随后，3-甲氧基-4,5-亚甲二氧基苯乙胺确实被证明是乌羽玉和的次要成分。 舒尔金报告说，3-甲氧基-4,5-亚甲二氧基苯乙胺在150至250毫克的剂量范围内具有活性。他指出，在这些剂量下，3-甲氧基-4,5-亚甲二氧基苯乙胺在作用上与麦司卡林有一些相似之处，产生平静的情绪提升、欣快感和视觉感知的轻度增强，但没有产生心像。舒尔金还指出（与麦司卡林相比），3-甲氧基-4,5-亚甲二氧基苯乙胺不会引起恶心。 (zh) Lophophine (MMDPEA or 3-methoxy-4,5-methylenedioxyphenethylamine) is a putative psychedelic and entactogen drug of the methylenedioxyphenethylamine class. It is the α-demethylated homologue of MMDA, and is also closely related to mescaline. (en) |
| rdfs:label |
Lophophine (en) 3-甲氧基-4,5-亚甲二氧基苯乙胺 (zh) |
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freebase:Lophophine yago-res:Lophophine wikidata:Lophophine dbpedia-sh:Lophophine dbpedia-sr:Lophophine dbpedia-zh:Lophophine https://global.dbpedia.org/id/XtA5 |
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dbr:List_of_adrenergic_drugs dbr:List_of_dopaminergic_drugs dbr:List_of_naturally_occurring_phenethylamines dbr:List_of_psychedelic_drugs dbr:MMDA_(drug) dbr:5-Methoxymethylone dbr:3-methoxy-4,5-methylenedioxyphenethylamine dbr:Methoxymethylenedioxyphenethylamine dbr:Substituted_phenethylamine dbr:PiHKAL dbr:2-(7-methoxy-1,3-benzodioxol-5-yl)ethanamine dbr:3-Methoxy-4,5-methylendioxyphenethylamine dbr:3-Methoxy-4,5-methylenedioxyphenethylamine dbr:3-methoxy-4,5-methylendioxyphenethylamine dbr:Homomyristicylamine dbr:MMDPEA |
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