3-Hydroxyphenazepam (original) (raw)
3-Hydroxyphenazepam is a benzodiazepine with hypnotic, sedative, anxiolytic, and anticonvulsant properties. It is an active metabolite of phenazepam, as well as the active metabolite of the benzodiazepine prodrug cinazepam. Relative to phenazepam, 3-hydroxyphenazepam has diminished myorelaxant properties, but is about equivalent in most other regards. Like other benzodiazepines, 3-hydroxyphenazepam behaves as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor with an EC50 value of 10.3 nM. It has been sold online as a designer drug.
| Property | Value |
|---|---|
| dbo:abstract | 3-Hydroxyphenazepam is a benzodiazepine with hypnotic, sedative, anxiolytic, and anticonvulsant properties. It is an active metabolite of phenazepam, as well as the active metabolite of the benzodiazepine prodrug cinazepam. Relative to phenazepam, 3-hydroxyphenazepam has diminished myorelaxant properties, but is about equivalent in most other regards. Like other benzodiazepines, 3-hydroxyphenazepam behaves as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor with an EC50 value of 10.3 nM. It has been sold online as a designer drug. (en) Le 3-hydroxyphénazépam est une benzodiazépine avec des effets anxiolytiques, hypnotiques, myorelaxants, amnésiants et anticonvulsivants.C'est un métabolite actif du phénazépam. (fr) Il 3-idrossifenazepam è uno psicofarmaco appartenente alla categoria delle benzodiazepine con proprietà ipnotiche, sedative, ansiolitiche e anticonvulsivanti. È un metabolita attivo sia del fenazepam, sia del cinazepam. Rispetto al fenazepam, il 3-idrossifenazepam ha proprietà miorilassanti ridotte, ma è pressoché equivalente alle altre benzodiazepine. (it) |
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| rdfs:comment | 3-Hydroxyphenazepam is a benzodiazepine with hypnotic, sedative, anxiolytic, and anticonvulsant properties. It is an active metabolite of phenazepam, as well as the active metabolite of the benzodiazepine prodrug cinazepam. Relative to phenazepam, 3-hydroxyphenazepam has diminished myorelaxant properties, but is about equivalent in most other regards. Like other benzodiazepines, 3-hydroxyphenazepam behaves as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor with an EC50 value of 10.3 nM. It has been sold online as a designer drug. (en) Le 3-hydroxyphénazépam est une benzodiazépine avec des effets anxiolytiques, hypnotiques, myorelaxants, amnésiants et anticonvulsivants.C'est un métabolite actif du phénazépam. (fr) Il 3-idrossifenazepam è uno psicofarmaco appartenente alla categoria delle benzodiazepine con proprietà ipnotiche, sedative, ansiolitiche e anticonvulsivanti. È un metabolita attivo sia del fenazepam, sia del cinazepam. Rispetto al fenazepam, il 3-idrossifenazepam ha proprietà miorilassanti ridotte, ma è pressoché equivalente alle altre benzodiazepine. (it) |
| rdfs:label | 3-Hydroxyphenazepam (en) 3-Idrossifenazepam (it) 3-Hydroxyphénazépam (fr) |
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