| dbo:abstract |
Arabinopyranosyl-N-methyl-N-nitrosourea, also known as Aranose (Араноза) is a cytostatic anticancer chemotherapeutic drug of an alkylating type. Chemically it is a nitrosourea derivative. It was developed in the Soviet Union in the 1970s. It was claimed by its developers that its advantages over other nitrosoureas are a relatively low hematological toxicity (compared to other nitrosoureas available at that time) and a wider therapeutic index, which allows for its outpatient administration. (en) Арабинопиранозил-N-метил-N-нитрозомочевина (Араноза) — цитостатический противоопухолевый химиотерапевтический лекарственный препарат алкилирующего типа действия, производное N-нитрозо-N-метилмочевины. Согласно утверждениям её разработчиков, преимущество арабинопиранозил-N-метил-N-нитрозомочевины перед другими производными нитрозомочевины — большая широта терапевтических доз и возможность применения в амбулаторных условиях. (ru) |
| dbo:alternativeName |
Aranose (en) |
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100.000000 (xsd:float) |
| dbo:casNumber |
167396-23-8 |
| dbo:fdaUniiCode |
7149VX7891 |
| dbo:pubchem |
208900 |
| dbo:thumbnail |
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http://oncology.ru/patient/medicine/aranoza/ |
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L01 (en) |
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| dbp:drugName |
Arabinopyranosyl-N-methyl-N-nitrosourea (en) |
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13 (xsd:integer) |
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1 (xsd:integer) |
| dbp:legalStatus |
Rx-only (en) |
| dbp:metabolism |
dbr:Hepatic |
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| dbp:pregnancyCategory |
D (en) |
| dbp:proteinBound |
50.0 |
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208900 (xsd:integer) |
| dbp:routesOfAdministration |
dbr:Intravenous_therapy |
| dbp:smiles |
CNN=O (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
BADMGRJDJPQBLS-UNTFVMJOSA-N (en) |
| dbp:synonyms |
Arabinopyranosyl methylnitrosourea; 3--1-methyl-1-nitrosourea (en) |
| dbp:tradename |
Aranose (en) |
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| dcterms:subject |
dbc:Arabinosides dbc:Nitrosoureas dbc:Soviet_inventions dbc:Amino_sugars dbc:Substances_discovered_in_the_1970s dbc:Drugs_in_the_Soviet_Union |
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| rdfs:comment |
Arabinopyranosyl-N-methyl-N-nitrosourea, also known as Aranose (Араноза) is a cytostatic anticancer chemotherapeutic drug of an alkylating type. Chemically it is a nitrosourea derivative. It was developed in the Soviet Union in the 1970s. It was claimed by its developers that its advantages over other nitrosoureas are a relatively low hematological toxicity (compared to other nitrosoureas available at that time) and a wider therapeutic index, which allows for its outpatient administration. (en) Арабинопиранозил-N-метил-N-нитрозомочевина (Араноза) — цитостатический противоопухолевый химиотерапевтический лекарственный препарат алкилирующего типа действия, производное N-нитрозо-N-метилмочевины. Согласно утверждениям её разработчиков, преимущество арабинопиранозил-N-метил-N-нитрозомочевины перед другими производными нитрозомочевины — большая широта терапевтических доз и возможность применения в амбулаторных условиях. (ru) |
| rdfs:label |
Arabinopyranosyl-N-methyl-N-nitrosourea (en) Арабинопиранозил-N-метил-N-нитрозомочевина (ru) |
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freebase:Arabinopyranosyl-N-methyl-N-nitrosourea yago-res:Arabinopyranosyl-N-methyl-N-nitrosourea wikidata:Arabinopyranosyl-N-methyl-N-nitrosourea dbpedia-ru:Arabinopyranosyl-N-methyl-N-nitrosourea https://global.dbpedia.org/id/3ksnG |
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wikipedia-en:Arabinopyranosyl-N-methyl-N-nitrosourea?oldid=1093432626&ns=0 |
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Arabinopyranosyl-N-methyl-N-nitrosourea (en) |
| is dbo:wikiPageRedirects of |
dbr:C7H13N3O6 dbr:Aranose dbr:Arabinopyranosyl_methylnitrosourea |
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wikipedia-en:Arabinopyranosyl-N-methyl-N-nitrosourea |
