Athymhormic syndrome (original) (raw)
Athymhormic syndrome (from Ancient Greek θυμός thūmós, "mood" or "affect", and hormḗ, "impulse", "drive" or "appetite"), psychic akinesia, or auto-activation deficit (AAD) is a rare psychopathological and neurological syndrome characterized by extreme passivity, apathy, blunted affect and a profound generalized loss of self-motivation and conscious thought. For example, a patient spent 45 minutes with his hands on a lawn mower, totally unable to initiate the act of mowing. This “kinetic blockade” disappeared instantaneously when his son told him to move. The existence of such symptoms in patients after damage to certain structures in the brain has been used in support of a physical model of motivation in human beings, wherein the limbic loop of the basal ganglia is the initiator of directe
| Property | Value |
|---|---|
| dbo:abstract | Athymhormic syndrome (from Ancient Greek θυμός thūmós, "mood" or "affect", and hormḗ, "impulse", "drive" or "appetite"), psychic akinesia, or auto-activation deficit (AAD) is a rare psychopathological and neurological syndrome characterized by extreme passivity, apathy, blunted affect and a profound generalized loss of self-motivation and conscious thought. For example, a patient spent 45 minutes with his hands on a lawn mower, totally unable to initiate the act of mowing. This “kinetic blockade” disappeared instantaneously when his son told him to move. The existence of such symptoms in patients after damage to certain structures in the brain has been used in support of a physical model of motivation in human beings, wherein the limbic loop of the basal ganglia is the initiator of directed action and thought. First described by French neurologist Dominique Laplane in 1982 as "PAP syndrome" (French: perte d'auto-activation psychique, or "loss of psychic autoactivation"), the syndrome is believed to be due to damage to areas of the basal ganglia or frontal cortex, specifically the striatum and globus pallidus, responsible for motivation and executive functions. It may occur without any preexisting psychiatric condition. (en) |
| dbo:wikiPageID | 5166016 (xsd:integer) |
| dbo:wikiPageLength | 3938 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1059569449 (xsd:integer) |
| dbo:wikiPageWikiLink | dbc:Psychopathological_syndromes dbr:Apathy dbr:Huntington's_disease dbr:Frontal_cortex dbr:Compulsive_behavior dbr:French_people dbr:Brain dbr:Motivation dbr:Major_depressive_disorder dbr:Progressive_supranuclear_palsy dbr:Syndrome dbr:Aboulia dbr:Ancient_Greek dbr:Akinetic_mutism dbr:Basal_ganglia dbr:Blunted_affect dbr:Globus_pallidus dbr:Psychiatry dbr:Athymhormia dbc:Symptoms_and_signs_of_mental_disorders dbr:Tic dbr:Ventral_tegmental_area dbr:Striatum |
| dbp:specialty | psychiatry (en) |
| dbp:wikiPageUsesTemplate | dbt:Empty_section dbt:Infobox_medical_condition_(new) dbt:Reflist dbt:Short_description |
| dcterms:subject | dbc:Psychopathological_syndromes dbc:Symptoms_and_signs_of_mental_disorders |
| gold:hypernym | dbr:Syndrome |
| rdf:type | owl:Thing wikidata:Q12136 yago:WikicatNeurologicalDisorders yago:Abstraction100002137 yago:Attribute100024264 yago:Condition113920835 yago:Disorder114052403 yago:NervousDisorder114084880 yago:PhysicalCondition114034177 dbo:Disease yago:State100024720 |
| rdfs:comment | Athymhormic syndrome (from Ancient Greek θυμός thūmós, "mood" or "affect", and hormḗ, "impulse", "drive" or "appetite"), psychic akinesia, or auto-activation deficit (AAD) is a rare psychopathological and neurological syndrome characterized by extreme passivity, apathy, blunted affect and a profound generalized loss of self-motivation and conscious thought. For example, a patient spent 45 minutes with his hands on a lawn mower, totally unable to initiate the act of mowing. This “kinetic blockade” disappeared instantaneously when his son told him to move. The existence of such symptoms in patients after damage to certain structures in the brain has been used in support of a physical model of motivation in human beings, wherein the limbic loop of the basal ganglia is the initiator of directe (en) |
| rdfs:label | Athymhormic syndrome (en) |
| owl:sameAs | freebase:Athymhormic syndrome yago-res:Athymhormic syndrome wikidata:Athymhormic syndrome https://global.dbpedia.org/id/4TCT2 |
| prov:wasDerivedFrom | wikipedia-en:Athymhormic_syndrome?oldid=1059569449&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Athymhormic_syndrome |
| is dbo:wikiPageRedirects of | dbr:Psychic_akinesia dbr:PAP_syndrome |
| is dbo:wikiPageWikiLink of | dbr:Akinetic_mutism dbr:Basal_ganglia dbr:Athymhormia dbr:Neuroanatomy_of_memory dbr:List_of_syndromes dbr:Psychic_akinesia dbr:PAP_syndrome |
| is foaf:primaryTopic of | wikipedia-en:Athymhormic_syndrome |