Bavituximab (original) (raw)

Property Value
dbo:abstract بافيتوكسيماب هو جسم مضاد وحيد النسيلة في طور التجارب السريرية لأجل استخدامه في علاج السرطان والأمراض الفيروسية. (ar) Bavituximab (PGN401) is a human-mouse chimeric monoclonal antibody against phosphatidylserine, which is a component of cell membranes that is exposed when a cell is transformed into solid tumor cancer cell or dies, and when cells are infected with hepatitis C. The process of cell death is highly controlled and so there usually no immune response to phosphatidylserine but when bavituximab binds to it, the conjugate appears to stimulate an immune response in humans. (en) Il Bavituximab è un anticorpo monoclonale chimerico, che è stato sperimentato come trattamento di tumori e infezioni virali.Il farmaco lega la fosfatidilserina che viene esposta sulla superficie di cellule animali atipiche, sui tumori e su sei differenti famiglie di virus. (it)
dbo:casNumber 648904-28-3
dbo:fdaUniiCode Q16CT95N25
dbo:wikiPageID 9124162 (xsd:integer)
dbo:wikiPageLength 7640 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID 1084697175 (xsd:integer)
dbo:wikiPageWikiLink dbr:Non-small_cell_lung_cancer dbr:Monoclonal_antibody dbc:Experimental_cancer_drugs dbr:Apoptosis dbr:Hepatitis_C dbr:Hepatocellular_carcinoma dbc:Monoclonal_antibodies_for_tumors dbr:Phosphatidylserine dbr:Influenza dbr:Malignant_transformation dbr:Solid_tumor dbr:Chimera_(protein) dbr:Lassa_fever_virus
dbp:atcPrefix none (en)
dbp:c 6446 (xsd:integer)
dbp:casNumber 648904 (xsd:integer)
dbp:chemspiderid none (en)
dbp:eliminationHalfLife 108000.0
dbp:h 9946 (xsd:integer)
dbp:mabType mab (en)
dbp:n 1702 (xsd:integer)
dbp:o 2042 (xsd:integer)
dbp:routesOfAdministration infusion (en)
dbp:s 42 (xsd:integer)
dbp:source xi/o (en)
dbp:target dbr:Phosphatidylserine
dbp:type mab (en)
dbp:unii Q16CT95N25 (en)
dbp:verifiedrevid 455435138 (xsd:integer)
dbp:wikiPageUsesTemplate dbt:Drugbox dbt:Reflist dbt:Rp dbt:Short_description dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Fdacite dbt:Monoclonals_for_tumors
dcterms:subject dbc:Experimental_cancer_drugs dbc:Monoclonal_antibodies_for_tumors
rdf:type owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:MonoclonalAntibody dbo:Drug
rdfs:comment بافيتوكسيماب هو جسم مضاد وحيد النسيلة في طور التجارب السريرية لأجل استخدامه في علاج السرطان والأمراض الفيروسية. (ar) Bavituximab (PGN401) is a human-mouse chimeric monoclonal antibody against phosphatidylserine, which is a component of cell membranes that is exposed when a cell is transformed into solid tumor cancer cell or dies, and when cells are infected with hepatitis C. The process of cell death is highly controlled and so there usually no immune response to phosphatidylserine but when bavituximab binds to it, the conjugate appears to stimulate an immune response in humans. (en) Il Bavituximab è un anticorpo monoclonale chimerico, che è stato sperimentato come trattamento di tumori e infezioni virali.Il farmaco lega la fosfatidilserina che viene esposta sulla superficie di cellule animali atipiche, sui tumori e su sei differenti famiglie di virus. (it)
rdfs:label بافيتوكسيماب (ar) Bavituximab (en) Bavituximab (it)
owl:sameAs yago-res:Bavituximab wikidata:Bavituximab dbpedia-ar:Bavituximab dbpedia-it:Bavituximab https://global.dbpedia.org/id/3M5ZX
prov:wasDerivedFrom wikipedia-en:Bavituximab?oldid=1084697175&ns=0
foaf:isPrimaryTopicOf wikipedia-en:Bavituximab
is dbo:wikiPageRedirects of dbr:C6446H9946N1702O2042S42
is dbo:wikiPageWikiLink of dbr:Monoclonal_antibody dbr:C6446H9946N1702O2042S42 dbr:Ipilimumab dbr:Humanized_antibody dbr:List_of_therapeutic_monoclonal_antibodies dbr:List_of_drugs:_Ba
is foaf:primaryTopic of wikipedia-en:Bavituximab