| dbo:abstract |
β-Peptide sind synthetische Peptide, bei denen im Gegensatz zu den biologischen Peptiden die Peptidbindung am β-Kohlenstoffatom liegt. β-Peptide gehören zu den Peptidmimetika. (de) Beta-peptides (β-peptides) are peptides derived from β-amino acids, in which the amino group is attached to the β-carbon (i.e. the carbon two atoms away from the carboxylate group). The parent β-amino acid is β-alanine (H2NCH2CH2CO2H), a common natural substance, but most examples feature substituents in place of one or more C-H bonds. β-peptides usually do not occur in nature. β-peptide-based antibiotics are being explored as ways of evading antibiotic resistance. Early studies in this field were published in 1996 by the group of Dieter Seebach and that of Samuel Gellman. (en) β-多肽（ Beta-多肽）是由β-氨基酸聚合而成的多肽。母体β-氨基酸是H2NCH2CH2COOH，但大多数的情况下，取代基取代了一个或多个CH键。唯一常见的天然存在的β氨基酸是β-丙氨酸。 自然界中一般不存在β-多肽。基于β肽的抗生素有潜力作为防止产生抗生素耐药性的方法，1996年由Dieter Seebach 小组和 Samuel Gellman 小组于发表相关的早期研究。 (zh) |
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| rdfs:comment |
β-Peptide sind synthetische Peptide, bei denen im Gegensatz zu den biologischen Peptiden die Peptidbindung am β-Kohlenstoffatom liegt. β-Peptide gehören zu den Peptidmimetika. (de) Beta-peptides (β-peptides) are peptides derived from β-amino acids, in which the amino group is attached to the β-carbon (i.e. the carbon two atoms away from the carboxylate group). The parent β-amino acid is β-alanine (H2NCH2CH2CO2H), a common natural substance, but most examples feature substituents in place of one or more C-H bonds. β-peptides usually do not occur in nature. β-peptide-based antibiotics are being explored as ways of evading antibiotic resistance. Early studies in this field were published in 1996 by the group of Dieter Seebach and that of Samuel Gellman. (en) β-多肽（ Beta-多肽）是由β-氨基酸聚合而成的多肽。母体β-氨基酸是H2NCH2CH2COOH，但大多数的情况下，取代基取代了一个或多个CH键。唯一常见的天然存在的β氨基酸是β-丙氨酸。 自然界中一般不存在β-多肽。基于β肽的抗生素有潜力作为防止产生抗生素耐药性的方法，1996年由Dieter Seebach 小组和 Samuel Gellman 小组于发表相关的早期研究。 (zh) |
| rdfs:label |
Β-Peptide (de) Beta-peptide (en) Β-多肽 (zh) |
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