dbo:abstract |
The c-myc internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of C-myc and allows cap-independent translation. The mammalian c-myc gene is a proto-oncogene which is required for cell proliferation, transformation and death. c-myc mRNA has an alternative method of translation via internal ribosome entry where ribosomes are recruited to the IRES located in the 5' UTR thus bypassing the typical eukaryotic cap-dependent translation pathway. (en) |
dbo:thumbnail |
wiki-commons:Special:FilePath/RF00216.jpg?width=300 |
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11420733 (xsd:integer) |
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1642 (xsd:nonNegativeInteger) |
dbo:wikiPageRevisionID |
919474635 (xsd:integer) |
dbo:wikiPageWikiLink |
dbr:C-myc dbr:Internal_ribosome_entry_site dbr:MRNA dbr:Eukaryota dbc:Cis-regulatory_RNA_elements dbr:Cis-regulatory_element dbr:Sequence_conservation dbr:Five_prime_untranslated_region dbr:Secondary_structure |
dbp:altsymbols |
c-myc_IRES (en) |
dbp:caption |
Predicted secondary structure and sequence conservation of IRES_c-myc (en) |
dbp:id |
RF00216 (en) |
dbp:name |
c-myc internal ribosome entry site (en) |
dbp:rfam |
RF00216 (en) |
dbp:rnaType |
dbr:Internal_ribosome_entry_site dbr:Cis-regulatory_element |
dbp:symbol |
IRES_c-myc (en) |
dbp:taxDomain |
dbr:Eukaryota |
dbp:wikiPageUsesTemplate |
dbt:Reflist dbt:GO dbt:SO dbt:Infobox_rfam dbt:Molecular-cell-biology-stub dbt:Rfam |
dct:subject |
dbc:Cis-regulatory_RNA_elements |
gold:hypernym |
dbr:Element |
rdf:type |
yago:WikicatCis-regulatoryRNAElements yago:Abstraction100002137 yago:Cognition100023271 yago:Component105868954 yago:Concept105835747 yago:Content105809192 yago:Idea105833840 yago:Part105867413 yago:PsychologicalFeature100023100 dbo:MilitaryUnit |
rdfs:comment |
The c-myc internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of C-myc and allows cap-independent translation. The mammalian c-myc gene is a proto-oncogene which is required for cell proliferation, transformation and death. c-myc mRNA has an alternative method of translation via internal ribosome entry where ribosomes are recruited to the IRES located in the 5' UTR thus bypassing the typical eukaryotic cap-dependent translation pathway. (en) |
rdfs:label |
C-myc internal ribosome entry site (IRES) (en) |
owl:sameAs |
freebase:C-myc internal ribosome entry site (IRES) yago-res:C-myc internal ribosome entry site (IRES) wikidata:C-myc internal ribosome entry site (IRES) https://global.dbpedia.org/id/4eUQf |
prov:wasDerivedFrom |
wikipedia-en:C-myc_internal_ribosome_entry_site_(IRES)?oldid=919474635&ns=0 |
foaf:depiction |
wiki-commons:Special:FilePath/RF00216.jpg |
foaf:isPrimaryTopicOf |
wikipedia-en:C-myc_internal_ribosome_entry_site_(IRES) |
is dbo:wikiPageRedirects of |
dbr:C-myc_IRES |
is dbo:wikiPageWikiLink of |
dbr:C-myc_IRES dbr:Internal_ribosome_entry_site |
is foaf:primaryTopic of |
wikipedia-en:C-myc_internal_ribosome_entry_site_(IRES) |