COMPASS complex (original) (raw)
Complex Proteins Associated with Set1, also known as COMPASS, is a conserved protein complex playing a major role as a H3K4me3 methylase in eukaryotes. Since it was first identified in 2001, other members of the COMPASS family of methylases with different functions have been discovered, in particular in humans. The COMPASS complex is an example of a trithorax-group protein. The MLL1/SET domain associated with the COMPASS complex have crystal structure. The gene Cps50 coordinates the construction of COMPASS.
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| dbo:abstract | Complex Proteins Associated with Set1, also known as COMPASS, is a conserved protein complex playing a major role as a H3K4me3 methylase in eukaryotes. Since it was first identified in 2001, other members of the COMPASS family of methylases with different functions have been discovered, in particular in humans. The Compass complex, or similar protein complexes, have been identified in species ranging from single celled fungi to humans. They play an important regulatory role in many invaluable biological processes including DNA repair, the progression of the cell cycle and transcription through the methylenation of histone lysines. The COMPASS complex is an example of a trithorax-group protein. The MLL1/SET domain associated with the COMPASS complex have crystal structure. The gene Cps50 coordinates the construction of COMPASS. (en) |
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| dbo:wikiPageLength | 3212 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1118270962 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:H3K4me3 dbc:Protein_complexes dbr:Eukaryote dbr:Protein_complex dbr:Methyltransferase dbr:Set1 dbr:Trithorax-group_proteins |
| dbp:wikiPageUsesTemplate | dbt:Protein-stub dbt:Reflist dbt:Short_description |
| dct:subject | dbc:Protein_complexes |
| rdfs:comment | Complex Proteins Associated with Set1, also known as COMPASS, is a conserved protein complex playing a major role as a H3K4me3 methylase in eukaryotes. Since it was first identified in 2001, other members of the COMPASS family of methylases with different functions have been discovered, in particular in humans. The COMPASS complex is an example of a trithorax-group protein. The MLL1/SET domain associated with the COMPASS complex have crystal structure. The gene Cps50 coordinates the construction of COMPASS. (en) |
| rdfs:label | COMPASS complex (en) |
| owl:sameAs | wikidata:COMPASS complex https://global.dbpedia.org/id/CBAMe |
| prov:wasDerivedFrom | wikipedia-en:COMPASS_complex?oldid=1118270962&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:COMPASS_complex |
| is dbo:wikiPageWikiLink of | dbr:Histone dbr:Set1 |
| is foaf:primaryTopic of | wikipedia-en:COMPASS_complex |