| dbo:abstract |
سيفكوينوم Cefquinome هو مضاد حيوي, الجيل الرابع من السيفالوسبورينات مع خصائص مضادة للجراثيم، ذو قيمة في علاج التهاب الضرع من بكتريا القولون والتهابات أخرى. ويستخدم فقط في الطب البيطري. (ar) Cefquinome is a fourth-generation cephalosporin with pharmacological and antibacterial properties valuable in the treatment of coliform mastitis and other infections. It is only used in veterinary applications. (en) セフキノム（英: cefquinome）とはセフェム系抗生物質の一つ。ウシの肺炎や、ブタやウシの乳房炎の治療に使用される動物用医薬品。分子式C23H26N6O9S3、分子量626.7。 (ja) Il cefquinome è una cefalosporina di quarta generazione con proprietà farmacologiche e antibatteriche utili nel trattamento delle mastiti coliformi e di altre infezioni. È utilizzato solo in applicazioni veterinarie. Il cefquinome è resistente alle beta-lattamasi. Chimicamente, la sua struttura zwitterionica può facilitare la rapida penetrazione attraverso le membrane biologiche, incluse le porine della parete cellulare batterica. Inoltre, ha una maggiore affinità per le proteine leganti la penicillina. La parte attiva della molecola è un nucleo beta-lattamico, mentre i principali gruppi funzionali sono un quinolinio quaternario, una porzione aminotiazolica e un insolito oxime O-alchilato. Il cefquinome agisce inibendo la sintesi della parete cellulare, ma ha una relativamente breve emivita, di circa due ore e mezza. È escreto immodificato nelle urine. (it) |
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87.000000 (xsd:float) |
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84957-30-2 |
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2103931 |
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Z74S078CWP |
| dbo:kegg |
D07652 |
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wiki-commons:Special:FilePath/Cefquinome.svg?width=300 |
| dbo:wikiPageExternalLink |
http://www.intervet.co.uk/Products_Public/Cephaguard_Injection/090_Product_Datasheet.asp https://web.archive.org/web/20050115193430/http:/www.intervet.co.uk/Products_Public/Cephaguard_Injection/090_Product_Datasheet.asp https://web.archive.org/web/20080514145531/https:/www.fda.gov/cvm/VMAC/VMAV0906Johnson.htm https://www.fda.gov/cvm/VMAC/VMAV0906Johnson.htm |
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dbr:Enterococcus dbr:Pasteurella_multocida dbr:Beta-lactamase dbr:Dermatitis dbr:Beta-lactam dbr:Betaine dbr:In_vitro dbr:In_vivo dbr:Staphylococcus_hyicus dbr:Bovine_respiratory_disease dbr:Staphylococcus dbr:Zwitterion dbr:Streptococcus dbr:Streptococcus_suis dbc:Cephalosporin_antibiotics dbr:Actinobacillus_pleuropneumoniae dbr:Cefepime dbr:Cefotaxime dbr:Cephalosporin dbr:Trimethylsilyl_iodide dbc:Thiazoles dbr:Curve_fitting dbr:PH dbr:Quaternary_ammonium_cation dbc:Quinolines dbc:Ketoximes dbr:Kidney dbr:Salmonella dbr:Pneumonia dbr:Antibiotic_resistance dbr:Campylobacter dbr:Cephalic_vein dbr:Oxime dbr:Intervet dbr:Parenteral_administration dbr:Water_solubility dbr:Vena_jugularis dbr:Porins dbr:(6''R'',7''R'')-7-[[<...,7,8-tetrahydroquinolinium_inner_salt dbr:2,3-cyclohexenopyridine dbr:5,6,7,8-tetrahydroquinoline dbr:File:Cefquinome_synthesis.svg dbr:Haemophilus_parasuis dbr:MSTFA dbr:Mastitis-metritis-agalactia_syndrome |
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G51 (en) |
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dbc:Cephalosporin_antibiotics dbc:Thiazoles dbc:Quinolines dbc:Ketoximes |
| gold:hypernym |
dbr:Cephalosporin |
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| rdfs:comment |
سيفكوينوم Cefquinome هو مضاد حيوي, الجيل الرابع من السيفالوسبورينات مع خصائص مضادة للجراثيم، ذو قيمة في علاج التهاب الضرع من بكتريا القولون والتهابات أخرى. ويستخدم فقط في الطب البيطري. (ar) Cefquinome is a fourth-generation cephalosporin with pharmacological and antibacterial properties valuable in the treatment of coliform mastitis and other infections. It is only used in veterinary applications. (en) セフキノム（英: cefquinome）とはセフェム系抗生物質の一つ。ウシの肺炎や、ブタやウシの乳房炎の治療に使用される動物用医薬品。分子式C23H26N6O9S3、分子量626.7。 (ja) Il cefquinome è una cefalosporina di quarta generazione con proprietà farmacologiche e antibatteriche utili nel trattamento delle mastiti coliformi e di altre infezioni. È utilizzato solo in applicazioni veterinarie. Il cefquinome agisce inibendo la sintesi della parete cellulare, ma ha una relativamente breve emivita, di circa due ore e mezza. È escreto immodificato nelle urine. (it) |
| rdfs:label |
سيفكوينوم (ar) Cefquinome (en) Cefquinome (it) セフキノム (ja) |
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freebase:Cefquinome yago-res:Cefquinome wikidata:Cefquinome dbpedia-ar:Cefquinome dbpedia-fa:Cefquinome dbpedia-it:Cefquinome dbpedia-ja:Cefquinome dbpedia-ro:Cefquinome dbpedia-sh:Cefquinome dbpedia-sr:Cefquinome https://global.dbpedia.org/id/XTjq |
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dbr:Qivitan dbr:C23H24N6O5S2 dbr:ATCvet_code_QJ01DE90 dbr:ATCvet_code_QJ51DA92 dbr:Cobactan dbr:Cobactan® |
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wikipedia-en:Cefquinome |
