Compartment (development) (original) (raw)
Compartments can be simply defined as separate, different, adjacent cell populations, which upon juxtaposition, create a lineage boundary. This boundary prevents cell movement from cells from different lineages across this barrier, restricting them to their compartment. Subdivisions are established by morphogen gradients and maintained by local cell-cell interactions, providing functional units with domains of different regulatory genes, which give rise to distinct fates.Compartment boundaries are found across species. In the hindbrain of vertebrate embryos, rhobomeres are compartments of common lineage outlined by expression of Hox genes. In invertebrates, the wing imaginal disc of Drosophila provides an excellent model for the study of compartments. Although other tissues, such as the a
| Property | Value |
|---|---|
| dbo:abstract | Compartments can be simply defined as separate, different, adjacent cell populations, which upon juxtaposition, create a lineage boundary. This boundary prevents cell movement from cells from different lineages across this barrier, restricting them to their compartment. Subdivisions are established by morphogen gradients and maintained by local cell-cell interactions, providing functional units with domains of different regulatory genes, which give rise to distinct fates.Compartment boundaries are found across species. In the hindbrain of vertebrate embryos, rhobomeres are compartments of common lineage outlined by expression of Hox genes. In invertebrates, the wing imaginal disc of Drosophila provides an excellent model for the study of compartments. Although other tissues, such as the abdomen, and even other imaginal discs are compartmentalized, much of our understanding of key concepts and molecular mechanisms involved in compartment boundaries has been derived from experimentation in the wing disc of the fruit fly. (en) Les compartiments, métamères ou segments sont des populations de cellules distinctes, différentes et adjacentes qui, lors de leur juxtaposition, créent une frontière entre lignées cellulaires. Cette frontière empêche le mouvement des cellules de différentes lignées à travers cette barrière, les limitant à leur compartiment. Les subdivisions sont établies par des gradients de morphogène et maintenues par des interactions cellule-cellule locales, fournissant aux cellules des compartiments différents gènes régulateurs, qui donnent lieu à des destins distincts. La métamérie est un trait partagé par de nombreuses espèces. Dans le rhombencéphale des embryons de vertébrés, les rhombomères sont des compartiments décrits par l'expression des gènes Hox. Chez les invertébrés, le disque imaginal alaire de la drosophile (Drosophila spp.) fournit un excellent modèle pour l'étude des compartiments. Bien que d'autres tissus, tels que l'abdomen ou encore d'autres disques imaginaux soient compartimentés, une grande partie de notre compréhension des mécanismes moléculaires impliqués dans la formation et l'utilité des compartiments est dérivée des études sur le disque alaire de la drosophile. (fr) |
| dbo:wikiPageID | 4642940 (xsd:integer) |
| dbo:wikiPageLength | 21645 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1050627002 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Cytoskeleton dbr:Vertebrate dbr:Decapentaplegic dbr:Developmental_biology dbr:Rhombomere dbr:Genetic_screen dbr:Myosin-heavy-chain_kinase dbr:Engrailed_(gene) dbr:Morphogen dbr:Myosin dbr:Clone_(cell_biology) dbr:Embryo dbr:Pattern_formation dbr:Programmed_cell_death dbr:Regional_specification dbr:CDH1_(gene) dbr:Adhesion dbr:Cell_(biology) dbr:Drosophila_embryogenesis dbr:Drosophila_melanogaster dbr:Anatomical_terms_of_location dbc:Developmental_biology dbr:Drosophila dbr:Cell_adhesion_molecule dbr:Cell_division dbr:Cell_fate_determination dbr:Cell_growth dbr:Ci_protein dbr:Regeneration_(biology) dbr:Regulator_gene dbr:Hedgehog_signaling_pathway dbr:Invertebrate dbr:Blastoderm dbr:Ectopic_expression dbr:Heredity dbr:Homeotic_selector_gene dbr:Signal_transduction dbr:Tension_(physics) dbr:Tissue_(biology) dbr:Hox_gene dbr:Y-27632 dbr:Smoothened dbr:Species dbr:Vertex_model dbr:Cell-cell_interaction dbr:Imaginal_disc dbr:Molecular_biology dbr:Rhombencephalon dbr:Rho_kinase dbr:Adhesion_molecules |
| dbp:wikiPageUsesTemplate | dbt:Reflist dbt:Developmental_biology |
| dcterms:subject | dbc:Developmental_biology |
| rdfs:comment | Compartments can be simply defined as separate, different, adjacent cell populations, which upon juxtaposition, create a lineage boundary. This boundary prevents cell movement from cells from different lineages across this barrier, restricting them to their compartment. Subdivisions are established by morphogen gradients and maintained by local cell-cell interactions, providing functional units with domains of different regulatory genes, which give rise to distinct fates.Compartment boundaries are found across species. In the hindbrain of vertebrate embryos, rhobomeres are compartments of common lineage outlined by expression of Hox genes. In invertebrates, the wing imaginal disc of Drosophila provides an excellent model for the study of compartments. Although other tissues, such as the a (en) Les compartiments, métamères ou segments sont des populations de cellules distinctes, différentes et adjacentes qui, lors de leur juxtaposition, créent une frontière entre lignées cellulaires. Cette frontière empêche le mouvement des cellules de différentes lignées à travers cette barrière, les limitant à leur compartiment. Les subdivisions sont établies par des gradients de morphogène et maintenues par des interactions cellule-cellule locales, fournissant aux cellules des compartiments différents gènes régulateurs, qui donnent lieu à des destins distincts. (fr) |
| rdfs:label | Compartment (development) (en) Compartiment (développement) (fr) |
| owl:sameAs | freebase:Compartment (development) wikidata:Compartment (development) dbpedia-fr:Compartment (development) https://global.dbpedia.org/id/4hzYB |
| prov:wasDerivedFrom | wikipedia-en:Compartment_(development)?oldid=1050627002&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Compartment_(development) |
| is dbo:wikiPageDisambiguates of | dbr:Compartment |
| is dbo:wikiPageWikiLink of | dbr:Peter_Anthony_Lawrence dbr:Index_of_genetics_articles dbr:Ginés_Morata dbr:Homeosis dbr:Zona_limitans_intrathalamica dbr:Compartment |
| is foaf:primaryTopic of | wikipedia-en:Compartment_(development) |