Conjugated estrogens/medroxyprogesterone acetate (original) (raw)

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Conjugated estrogens/medroxyprogesterone acetate (CEs/MPA), sold under the brand names Prempro and Premphase, is a combination product of conjugated equine estrogens (Premarin), an estrogen collected from horse urine, and medroxyprogesterone acetate (Provera), a progestogen, which is used in menopausal hormone therapy for the treatment of menopausal symptoms. In 2018, it was the 308th most commonly prescribed medication in the United States, with more than 1 million prescriptions.

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dbo:abstract Conjugated estrogens/medroxyprogesterone acetate (CEs/MPA), sold under the brand names Prempro and Premphase, is a combination product of conjugated equine estrogens (Premarin), an estrogen collected from horse urine, and medroxyprogesterone acetate (Provera), a progestogen, which is used in menopausal hormone therapy for the treatment of menopausal symptoms. In 2018, it was the 308th most commonly prescribed medication in the United States, with more than 1 million prescriptions. (en)
dbo:alternativeName Prempro, Premphase, Premique (en)
dbo:casNumber 135843-32-2
dbo:pubchem 75124299
dbo:wikiPageExternalLink https://druginfo.nlm.nih.gov/drugportal/name/estrogens%20mixture%20with%20medroxyprogesterone%20acetate
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dbo:wikiPageWikiLink dbr:List_of_combined_sex-hormonal_preparations dbr:Progestogen dbr:Menopause dbr:Conjugated_estrogens dbr:Medroxyprogesterone_acetate dbr:Estradiol/medroxyprogesterone_acetate dbr:Estrogen_(medication) dbr:Oral_administration dbc:Combined_estrogen–progestogen_formulations dbr:Combination_drug dbr:Symptom dbr:Estradiol_cypionate/medroxyprogesterone_acetate dbr:Menopausal_hormone_therapy
dbp:atcPrefix none (en)
dbp:casNumber 135843 (xsd:integer)
dbp:class dbr:Progestogen dbr:Estrogen_(medication)
dbp:component Conjugated estrogens (en) Medroxyprogesterone acetate (en)
dbp:legalStatus Rx-only (en)
dbp:legalUk POM (en)
dbp:legalUs Rx-only (en)
dbp:pregnancyAu D (en)
dbp:pregnancyCategory Contraindicated (en)
dbp:pregnancyUs N (en)
dbp:pubchem 75124299 (xsd:integer)
dbp:routesOfAdministration dbr:Oral_administration
dbp:smiles CC1CC2CC4C.CC12CCC3CCCC4=C3C=CCOSO.CC12CCC3CC1CCC2=O.CC12CCC3=CC=CC4=C3C=CCOSO (en)
dbp:stdinchi 1 (xsd:integer)
dbp:stdinchikey OZPWNCNLFBVVEN-RFYLDXRNSA-N (en)
dbp:synonyms CEs/MPA; CEEs/MPA (en)
dbp:tradename Prempro, Premphase, Premique (en)
dbp:type combo (en)
dbp:wikiPageUsesTemplate dbt:Cite_web dbt:Drugbox dbt:Estrogen_receptor_modulators dbt:Genito-urinary-drug-stub dbt:Nbsp dbt:Portal_bar dbt:Progesterone_receptor_modulators dbt:Reflist dbt:Use_dmy_dates dbt:Estrogens_and_antiestrogens dbt:Progestogens_and_antiprogestogens dbt:Results_of_the_Women's_Health_Initiati..._therapy_randomized_controlled_trials dbt:Risk_of_venous_thromboembolism_with_ho..._birth_control_pills_(QResearch/CPRD) dbt:Drugs.com
dcterms:subject dbc:Combined_estrogen–progestogen_formulations
rdf:type owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:CombinationDrug dbo:Drug
rdfs:comment Conjugated estrogens/medroxyprogesterone acetate (CEs/MPA), sold under the brand names Prempro and Premphase, is a combination product of conjugated equine estrogens (Premarin), an estrogen collected from horse urine, and medroxyprogesterone acetate (Provera), a progestogen, which is used in menopausal hormone therapy for the treatment of menopausal symptoms. In 2018, it was the 308th most commonly prescribed medication in the United States, with more than 1 million prescriptions. (en)
rdfs:label Conjugated estrogens/medroxyprogesterone acetate (en)
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is dbo:wikiPageWikiLink of dbr:List_of_combined_sex-hormonal_preparations dbr:Medroxyprogesterone_acetate dbr:Estradiol/medroxyprogesterone_acetate dbr:Estradiol_cypionate/medroxyprogesterone_acetate dbr:Conjugated_estrogens;_medroxyprogesterone dbr:PremPhase dbr:PremPro dbr:Premelle dbr:Premique dbr:Premphase dbr:Prempro
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