Dimethyldioctadecylammonium bromide (original) (raw)
Dimethyldioctadecylammonium bromide (also dioctadecyldimethylammonium bromide or DODAB) is a double-chained quaternary ammonium surfactant that forms unilamellar vesicles (ULVs) in water. Among various preparation methods, the ‘‘hot-water” method offers a simple procedure to prepare DODAB cationic vesicles by simply dissolving the DODAB in hot water above 50 °C, i.e., chain melting (main) transition, Tm.In general, the DSC thermograms of the unsonicated DODAB dispersions are dominated by two endotherms; the pre- (35–36 °C) and main transition (42.7–45 °C) peaks. Moreover, in literature reported the presence of a thirdendotherm (post transition) at 52.2 °C.The main transition (Tm) is ascribed to gel to liquid-crystalline phase transition in which the alkyl chains transform from solidlike to
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| dbo:abstract | Dimethyldioctadecylammonium bromide (also dioctadecyldimethylammonium bromide or DODAB) is a double-chained quaternary ammonium surfactant that forms unilamellar vesicles (ULVs) in water. Among various preparation methods, the ‘‘hot-water” method offers a simple procedure to prepare DODAB cationic vesicles by simply dissolving the DODAB in hot water above 50 °C, i.e., chain melting (main) transition, Tm.In general, the DSC thermograms of the unsonicated DODAB dispersions are dominated by two endotherms; the pre- (35–36 °C) and main transition (42.7–45 °C) peaks. Moreover, in literature reported the presence of a thirdendotherm (post transition) at 52.2 °C.The main transition (Tm) is ascribed to gel to liquid-crystalline phase transition in which the alkyl chains transform from solidlike to liquid-like state. The 10 mM DODAB is a critical concentration, below which the dispersions consist of large polydispersed unilamellar vesicles (ULVs) that exhibit a local (chain melting) transition at 43 °C, beyond which a structural transition occurs: ULVs --> MLVs (multilamellar vesicles) as indicated by the sudden increase in the dynamic moduli. However, above 10 mM DODAB, the dispersions are mostly formed by ULVs in coexistence with lamellar fragments resulting in a network that shows a rheogram similar to that of hexagonal liquid-crystalline phase. (en) Il bromuro di diottadecildimetilammonio (noto in letteratura con l'abbreviazione DODAB, dall'inglese dioctadecyldimethylammonium bromide) è un agente tensioattivo cationico. Esso è noto poiché forma in acqua vescicole unilamellari (ULVs). Tra i vari metodi per la preparazione delle vescicole cationiche DODAB ricordiamo quello dell'acqua calda: si dissolve il DODAB in acqua calda superiore a 50 °C in modo da raggiungere il punto di fusione della catena Tm (transizione principale). In generale i termogrammi DSC (Calorimetria differenziale a scansione) delle dispersioni non sonicate DODAB sono dominati da due picchi endotermici: uno relativo ad una pre-transizione (35-36 °C) e l'altro relativo alla transizione principale (42.7-45 °C). Inoltre può essere presente, a particolari concentrazioni, un terzo picco relativo ad una post-transizione (52.2 °C).La transizione principale è attribuita ad una transizione di fase gel-liquido cristallina, in cui le catene alchiliche si trasformano da solid-like a liquid-like. (it) |
| dbo:alternativeName | Distearyldimethylammonium bromide (en) |
| dbo:iupacName | N,N-Dimethyl-N-octadecyloctadecan-1-aminium bromide (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/Distearyldimonium_chloride.png?width=300 |
| dbo:wikiPageID | 24208026 (xsd:integer) |
| dbo:wikiPageLength | 4015 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1023340941 (xsd:integer) |
| dbo:wikiPageWikiLink | dbc:Cationic_surfactants dbc:Ammonium_compounds dbr:Vesicle_(biology_and_chemistry) dbr:Gel dbr:Concentration dbr:Transition_state dbc:Soft_matter dbr:Cetrimonium_bromide dbr:Cetrimonium_chloride dbr:Dispersion_(chemistry) dbr:Differential_scanning_calorimetry dbc:Bromides dbc:Colloidal_chemistry dbr:Didecyldimethylammonium_chloride dbr:Dimethyldioctadecylammonium_chloride dbr:Cationic dbr:Surfactant |
| dbp:imagefilel | Distearyldimonium chloride.png (en) |
| dbp:imagefiler | Br-.svg (en) |
| dbp:imagesizel | 260 (xsd:integer) |
| dbp:imagesizer | 20 (xsd:integer) |
| dbp:othernames | Distearyldimethylammonium bromide (en) |
| dbp:pin | N,N-Dimethyl-N-octadecyloctadecan-1-aminium bromide (en) |
| dbp:wikiPageUsesTemplate | dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Reflist dbt:Cascite dbt:Fdacite dbt:GHS07 dbt:H-phrases dbt:P-phrases |
| dcterms:subject | dbc:Cationic_surfactants dbc:Ammonium_compounds dbc:Soft_matter dbc:Bromides dbc:Colloidal_chemistry |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 dbo:ChemicalCompound |
| rdfs:comment | Dimethyldioctadecylammonium bromide (also dioctadecyldimethylammonium bromide or DODAB) is a double-chained quaternary ammonium surfactant that forms unilamellar vesicles (ULVs) in water. Among various preparation methods, the ‘‘hot-water” method offers a simple procedure to prepare DODAB cationic vesicles by simply dissolving the DODAB in hot water above 50 °C, i.e., chain melting (main) transition, Tm.In general, the DSC thermograms of the unsonicated DODAB dispersions are dominated by two endotherms; the pre- (35–36 °C) and main transition (42.7–45 °C) peaks. Moreover, in literature reported the presence of a thirdendotherm (post transition) at 52.2 °C.The main transition (Tm) is ascribed to gel to liquid-crystalline phase transition in which the alkyl chains transform from solidlike to (en) Il bromuro di diottadecildimetilammonio (noto in letteratura con l'abbreviazione DODAB, dall'inglese dioctadecyldimethylammonium bromide) è un agente tensioattivo cationico. Esso è noto poiché forma in acqua vescicole unilamellari (ULVs). Tra i vari metodi per la preparazione delle vescicole cationiche DODAB ricordiamo quello dell'acqua calda: si dissolve il DODAB in acqua calda superiore a 50 °C in modo da raggiungere il punto di fusione della catena Tm (transizione principale). (it) |
| rdfs:label | Dimethyldioctadecylammonium bromide (en) DODAB (it) |
| owl:sameAs | yago-res:Dimethyldioctadecylammonium bromide wikidata:Dimethyldioctadecylammonium bromide dbpedia-it:Dimethyldioctadecylammonium bromide https://global.dbpedia.org/id/3Quh2 |
| prov:wasDerivedFrom | wikipedia-en:Dimethyldioctadecylammonium_bromide?oldid=1023340941&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Br-.svg wiki-commons:Special:FilePath/Distearyldimonium_chloride.png |
| foaf:isPrimaryTopicOf | wikipedia-en:Dimethyldioctadecylammonium_bromide |
| is dbo:wikiPageRedirects of | dbr:DODAB |
| is dbo:wikiPageWikiLink of | dbr:DODAB dbr:Dimethyldioctadecylammonium_chloride |
| is foaf:primaryTopic of | wikipedia-en:Dimethyldioctadecylammonium_bromide |
