| dbo:abstract |
Delta-1-catenin and Delta-2-catenin are members of a subfamily of proteins with ten Armadillo-repeats. Delta-2-catenin is expressed in the brain where it is important for normal cognitive development. Like beta-catenin and gamma-catenin, delta-catenins seem to interact with Presenilins. These catenin-presenilin interaction have implications for cadherin function and regulation of cell-to-cell adhesion. While beta-catenin acts as a transcription regulatory protein in the Wnt/TCF pathway, delta-catenin 1 has been implicated as a regulator of the NF-κB transcription factor. Palmitoylation of delta-catenin seems to coordinate activity-dependent changes in synaptic adhesion molecules, synapse structure, and receptor localizations that are involved in memory formation. (en) Les delta-caténines, représentés par les caténines (du latin, catena = chaîne) Delta-1 et Delta-2 sont des membres de la super-famille des protéines à répétitions . (fr) Дельта-катенін 1 і дельта-катенін 2 — це члени субродини протеїнів з десятьма повтореннями амінокислотних залишків (англ. Armadillo-repeats). (uk) |
| dbo:arm |
p q |
| dbo:band |
12.1 15.2 |
| dbo:chromosome |
11 5 |
| dbo:entrezgene |
1500 1501 |
| dbo:hgncid |
2515 2516 |
| dbo:omim |
601045 (xsd:integer) 604275 (xsd:integer) |
| dbo:refseq |
NM_001331 NM_001332 |
| dbo:symbol |
CTNND CTNND1 CTNND2 |
| dbo:uniprot |
O60716 Q9UQB3 |
| dbo:wikiPageID |
10881399 (xsd:integer) |
| dbo:wikiPageLength |
3480 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1116590771 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Cadherin dbr:Presenilin dbr:Beta-catenin dbr:NF-κB dbr:CTNND1 dbr:Plakoglobin dbc:Catenins dbc:Armadillo-repeat-containing_proteins dbr:Catenin dbr:Wnt_signaling_pathway dbr:Palmitoylation dbr:Armadillo-repeats |
| dbp:altsymbols |
CTNND (en) |
| dbp:arm |
p (en) q (en) |
| dbp:band |
12.100000 (xsd:double) 15.200000 (xsd:double) |
| dbp:chromosome |
5 (xsd:integer) 11 (xsd:integer) |
| dbp:entrezgene |
1500 (xsd:integer) 1501 (xsd:integer) |
| dbp:hgncid |
2515 (xsd:integer) 2516 (xsd:integer) |
| dbp:name |
dbr:CTNND1 catenin , delta 2 (en) |
| dbp:omim |
601045 (xsd:integer) 604275 (xsd:integer) |
| dbp:refseq |
NM_001331 (en) NM_001332 (en) |
| dbp:symbol |
CTNND1 (en) CTNND2 (en) |
| dbp:uniprot |
O60716 (en) Q9UQB3 (en) |
| dbp:wikiPageUsesTemplate |
dbt:Gene-11-stub dbt:Reflist dbt:Short_description dbt:Infobox_protein dbt:Cytoskeletal_Proteins |
| dcterms:subject |
dbc:Catenins dbc:Armadillo-repeat-containing_proteins |
| gold:hypernym |
dbr:Members |
| rdf:type |
owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Protein yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 umbel-rc:ProteinMolecule |
| rdfs:comment |
Les delta-caténines, représentés par les caténines (du latin, catena = chaîne) Delta-1 et Delta-2 sont des membres de la super-famille des protéines à répétitions . (fr) Дельта-катенін 1 і дельта-катенін 2 — це члени субродини протеїнів з десятьма повтореннями амінокислотних залишків (англ. Armadillo-repeats). (uk) Delta-1-catenin and Delta-2-catenin are members of a subfamily of proteins with ten Armadillo-repeats. Delta-2-catenin is expressed in the brain where it is important for normal cognitive development. Like beta-catenin and gamma-catenin, delta-catenins seem to interact with Presenilins. These catenin-presenilin interaction have implications for cadherin function and regulation of cell-to-cell adhesion. While beta-catenin acts as a transcription regulatory protein in the Wnt/TCF pathway, delta-catenin 1 has been implicated as a regulator of the NF-κB transcription factor. (en) |
| rdfs:label |
Delta catenin (en) Delta-caténine (fr) Дельта-катенін (uk) |
| owl:sameAs |
freebase:Delta catenin yago-res:Delta catenin wikidata:Delta catenin dbpedia-fa:Delta catenin dbpedia-fr:Delta catenin dbpedia-uk:Delta catenin https://global.dbpedia.org/id/4isfC |
| prov:wasDerivedFrom |
wikipedia-en:Delta_catenin?oldid=1116590771&ns=0 |
| foaf:isPrimaryTopicOf |
wikipedia-en:Delta_catenin |
| foaf:name |
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) (en) catenin (cadherin-associated protein), delta 1 (en) |
| is dbo:wikiPageRedirects of |
dbr:CTNND2 dbr:Delta-catenine |
| is dbo:wikiPageWikiLink of |
dbr:Cyclin-dependent_kinase_5 dbr:P120_(protein) dbr:Cri_du_chat_syndrome dbr:Adherens_junction dbr:Catenin dbr:CTNND2 dbr:PSEN1 dbr:Palmitoylation dbr:Delta-catenine |
| is foaf:primaryTopic of |
wikipedia-en:Delta_catenin |