| dbo:abstract |
Ditolylguanidine is a sigma receptor agonist. It is somewhat selective for sigma receptors, but non-selective between the two sigma receptor subtypes, binding to both σ1 and σ2 with equal affinity. It has neuroprotective and antidepressant effects, and potentiates the effects of NMDA antagonists. (en) N,N′-Di-o-tolylguanidin ist eine chemische Verbindung aus der Gruppe der Guanidinderivate. (de) |
| dbo:casNumber |
97-39-2 |
| dbo:chEMBL |
282433 |
| dbo:fdaUniiCode |
LL2P01I17O |
| dbo:pubchem |
7333 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/1,3-Ditolylguanidine.svg?width=300 |
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dbc:Guanidines dbr:Antidepressant dbr:Aptiganel dbc:Sigma_agonists dbc:2-Tolyl_compounds dbr:Sigma_receptor dbr:Neuroprotective dbr:NMDA_antagonist |
| dbp:atcPrefix |
none (en) |
| dbp:c |
15 (xsd:integer) |
| dbp:casNumber |
97 (xsd:integer) |
| dbp:chembl |
282433 (xsd:integer) |
| dbp:chemspiderid |
7056 (xsd:integer) |
| dbp:h |
17 (xsd:integer) |
| dbp:iupacName |
12 (xsd:integer) |
| dbp:iupharLigand |
6684 (xsd:integer) |
| dbp:n |
3 (xsd:integer) |
| dbp:pubchem |
7333 (xsd:integer) |
| dbp:smiles |
N\c2ccccc2C (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
OPNUROKCUBTKLF-UHFFFAOYSA-N (en) |
| dbp:unii |
LL2P01I17O (en) |
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414433472 (xsd:integer) |
| dbp:width |
200 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Drugbox dbt:Nervous-system-drug-stub dbt:Short_description dbt:Cascite dbt:Chemspidercite dbt:Ebicite dbt:Fdacite dbt:Stdinchicite dbt:Sigma_receptor_modulators |
| dcterms:subject |
dbc:Guanidines dbc:Sigma_agonists dbc:2-Tolyl_compounds |
| gold:hypernym |
dbr:Agonist |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug umbel-rc:DrugProduct |
| rdfs:comment |
Ditolylguanidine is a sigma receptor agonist. It is somewhat selective for sigma receptors, but non-selective between the two sigma receptor subtypes, binding to both σ1 and σ2 with equal affinity. It has neuroprotective and antidepressant effects, and potentiates the effects of NMDA antagonists. (en) N,N′-Di-o-tolylguanidin ist eine chemische Verbindung aus der Gruppe der Guanidinderivate. (de) |
| rdfs:label |
N,N′-Di-o-tolylguanidin (de) Ditolylguanidine (en) |
| owl:sameAs |
freebase:Ditolylguanidine wikidata:Ditolylguanidine dbpedia-de:Ditolylguanidine dbpedia-sh:Ditolylguanidine dbpedia-sr:Ditolylguanidine https://global.dbpedia.org/id/3wkuD |
| prov:wasDerivedFrom |
wikipedia-en:Ditolylguanidine?oldid=1115707907&ns=0 |
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wiki-commons:Special:FilePath/1,3-Ditolylguanidine.svg |
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| is dbo:wikiPageRedirects of |
dbr:C15H17N3 dbr:Di-o-tolylguanidine |
| is dbo:wikiPageWikiLink of |
dbr:Aptiganel dbr:C15H17N3 dbr:Alazocine dbr:Opipramol dbr:Sigma_receptor dbr:Di-o-tolylguanidine |
| is foaf:primaryTopic of |
wikipedia-en:Ditolylguanidine |
