| dbo:alternativeName |
Prothiaden, others (en) |
| dbo:bioavailability |
30.000000 (xsd:float) |
| dbo:casNumber |
897-15-4 113-53-1 |
| dbo:chEBI |
36803 |
| dbo:chEMBL |
108947 |
| dbo:description |
para izomerów cis-trans (pl) Cis/trans-Isomerenpaar (de) pair of cis–trans isomers (en) antidepresivo tricíclico (es) antidepressivo triciclico (it) |
| dbo:drugbank |
DB09167 |
| dbo:fdaUniiCode |
3H0042311V W13O82Z7HL |
| dbo:kegg |
D07872 |
| dbo:pubchem |
5284550 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Dosulepin2DACS2.svg?width=300 |
| dbo:wikiPageExternalLink |
https://kidbdev.med.unc.edu/databases/pdsp.php%3FknowID=0&kiKey=&receptorDD=&receptor=&speciesDD=&species=&sourcesDD=&source=&hotLigandDD=&hotLigand=&testLigandDD=&testFreeRadio=testFreeRadio&testLigand=dothiepin&referenceDD=&reference=&KiGreater=&KiLess=&kiAllRadio=all&doQuery=Submit+Query |
| dbo:wikiPageWikiLink |
dbr:Hyponatremia dbr:Liver_failure dbr:Agranulocytosis dbr:Alpha-1_adrenergic_receptor dbr:Muscarinic_acetylcholine_receptor dbr:Receptor_antagonist dbr:Serotonin_transporter dbr:Australia dbr:English_language dbr:Europe dbr:Feces dbr:French_language dbr:German_language dbr:India dbr:Italian_language dbr:Japan dbr:Malaysia dbr:New_Zealand dbr:Singapore dbr:South_Africa dbr:Spanish_language dbr:Taiwan dbr:United_Kingdom dbr:United_States dbr:Serotonin–norepinephrine_reuptake_inhibitor dbr:Tricyclic_antidepressant dbr:Oxidation dbr:Ataxia dbr:Canada dbr:Hong_Kong dbr:Jaundice dbr:Liver dbr:Myocardial_infarction dbr:Peripheral_neuropathy dbr:Glucuronide dbr:Hepatitis dbr:Ring_(chemistry) dbc:Sodium_channel_blockers dbr:Chemical_structure dbr:Major_depressive_disorder dbr:Toxicity dbr:Depression_(mood) dbr:Salt_(chemistry) dbr:Antihistamine dbr:Serotonin dbr:Amitriptyline dbr:Clomipramine dbr:Imipramine dbr:Histamine_H1_receptor dbr:Eosinophilia dbr:Pharmacodynamics dbr:Galactorrhea dbr:Stomatitis dbr:Epilepsy dbr:Urine dbr:Hypomania dbr:Norepinephrine dbr:Ileus dbr:Norepinephrine_transporter dbr:Voltage-gated_sodium_channel dbr:Stereoisomerism dbr:5-HT2_receptor dbr:Depressant dbr:Gynecomastia dbr:Anticholinergic dbr:Demethylation dbr:Norepinephrine_reuptake_inhibitor dbr:Side_chain dbr:Guanethidine dbr:Hydrochloride dbr:Trimipramine dbr:Sodium_channel_blocker dbr:5-HT2A_receptor dbr:Histamine dbr:Paresthesia dbr:Serotonin_reuptake_inhibitor dbc:Alpha-1_blockers dbr:Thrombocytopenia dbr:Alpha-2_adrenergic_receptor dbr:Oral_administration dbr:Atypical_facial_pain dbr:Serotonin_syndrome dbr:Urinary_retention dbr:5-HT1A_receptor dbr:Glucuronidation dbr:Doxepin dbr:Reuptake_inhibitor dbr:Reuptake dbr:Muscarinic_acetylcholine_receptor_M4 dbr:Extrapyramidal_symptoms dbc:Tricyclic_antidepressants dbc:Muscarinic_antagonists dbc:Dibenzothiepines dbc:Analgesics dbc:Antihistamines dbc:Serotonin_receptor_antagonists dbc:Serotonin–norepinephrine_reuptake_inhibitors dbr:Conjugation_(biochemistry) dbr:Muscarinic_acetylcholine_receptor_M1 dbr:Muscarinic_acetylcholine_receptor_M2 dbr:Muscarinic_acetylcholine_receptor_M3 dbc:Dimethylamino_compounds dbr:Muscarinic_acetylcholine_receptor_M5 dbr:Dyspepsia dbr:Electrocardiogram dbr:Latin_language dbr:Generic_term dbr:Delusions dbr:Hallucinations dbr:Platelets dbr:Diuretics dbr:Overdose dbr:Tricyclic_compound dbr:Blood-brain_barrier dbr:Metabolites dbr:Dibenzothiepine dbr:Antiadrenergic dbr:Antiserotonergic dbr:Elimination_half-life dbr:H1_receptor dbr:Ring_system_(chemistry) dbr:Terminal_half-life dbr:Tertiary_amine dbr:Secondary_amine |
| dbp:atcPrefix |
N06 (en) |
| dbp:atcSuffix |
AA16 (en) |
| dbp:bioavailability |
30.0 (dbd:perCent) |
| dbp:c |
19 (xsd:integer) |
| dbp:casNumber |
897 (xsd:integer) 113-53-1 (en) |
| dbp:chebi |
36803 (xsd:integer) |
| dbp:chembl |
108947 (xsd:integer) |
| dbp:chemspiderid |
4447605 (xsd:integer) |
| dbp:drugbank |
DB09167 (en) |
| dbp:eliminationHalfLife |
-120600.0 (dbd:second) -164520.0 (dbd:second) -86040.0 (dbd:second) -91800.0 (dbd:second) |
| dbp:excretion |
Feces: 15% (en) Urine: 56% (en) |
| dbp:h |
21 (xsd:integer) |
| dbp:image |
Dosulepin-from-HCl-1987-xtal-CCDC-1160822.png (en) |
| dbp:imageClass |
skin-invert-image (en) |
| dbp:index2Label |
HCl (en) |
| dbp:iupacName |
-3 (xsd:integer) |
| dbp:kegg |
D07872 (en) |
| dbp:legalAu |
S4 (en) |
| dbp:metabolism |
Hepatic (en) |
| dbp:metabolites |
Northiaden, dothiepin sulfoxide, northiaden sulfoxide, glucuronide conjugates (en) |
| dbp:n |
1 (xsd:integer) |
| dbp:pregnancyAu |
C (en) |
| dbp:proteinBound |
84.0 (dbd:perCent) |
| dbp:pubchem |
5284550 (xsd:integer) |
| dbp:routesOfAdministration |
dbr:Oral_administration |
| dbp:s |
1 (xsd:integer) |
| dbp:smiles |
CNCC/C=C/1\C2=CC=CC=C2CSC3=CC=CC=C31 (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
PHTUQLWOUWZIMZ-GZTJUZNOSA-N (en) |
| dbp:synonyms |
IZ-914, KS-1596 (en) |
| dbp:title |
dbr:Pharmacodynamics |
| dbp:titlestyle |
background:#ccccff (en) |
| dbp:tradename |
Prothiaden, others (en) |
| dbp:unii |
3 (xsd:integer) W13O82Z7HL (en) |
| dbp:usan |
dothiepin (en) |
| dbp:verifiedfields |
changed (en) |
| dbp:verifiedrevid |
448788673 (xsd:integer) |
| dbp:watchedfields |
changed (en) |
| dbp:width |
200 (xsd:integer) 225 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Histamine_receptor_modulators dbt:Neuropathic_pain_and_fibromyalgia_pharmacotherapies dbt:Tricyclics dbt:Monoamine_reuptake_inhibitors dbt:Drugbox dbt:Adrenergic_receptor_modulators dbt:Ion_channel_modulators dbt:Muscarinic_acetylcholine_receptor_modulators dbt:Abbr dbt:Abbrlink dbt:Antidepressants dbt:Cascite dbt:Chemspidercite dbt:Distinguish dbt:Div_col dbt:Div_col_end dbt:Drugs.com dbt:Ebicite dbt:Fdacite dbt:Keggcite dbt:Main dbt:Navboxes dbt:Reflist dbt:See_also dbt:Serotonin_receptor_modulators dbt:Short_description dbt:Stdinchicite |
| dct:subject |
dbc:Sodium_channel_blockers dbc:Alpha-1_blockers dbc:Tricyclic_antidepressants dbc:Dibenzothiepines dbc:Analgesics dbc:Antihistamines dbc:Serotonin_receptor_antagonists dbc:Serotonin–norepinephrine_reuptake_inhibitors dbc:M1_receptor_antagonists dbc:M2_receptor_antagonists dbc:M3_receptor_antagonists dbc:M4_receptor_antagonists dbc:M5_receptor_antagonists dbc:Dimethylamino_compounds dbc:CYP2D6_inhibitors |
| gold:hypernym |
dbr:Antidepressant |
| rdf:type |
owl:Thing dul:ChemicalObject wikidata:Q8386 dbo:ChemicalSubstance dbo:ChemicalSubstance dbo:Drug dbo:Drug dbo:Drug umbel-rc:DrugProduct |
| rdfs:label |
Dosulepin (en) Dosulepin (de) Dosulepina (it) Dosulepina (pl) Dosulepina (pt) |
| rdfs:seeAlso |
dbr:Pharmacology_of_antidepressants |
| owl:differentFrom |
dbr:Doxepin |
| owl:sameAs |
freebase:Dosulepin yago-res:Dosulepin wikidata:Dosulepin wikidata:Dosulepin dbpedia-de:Dosulepin dbpedia-it:Dosulepin dbpedia-pl:Dosulepin dbpedia-pt:Dosulepin dbpedia-azb:Dosulepin dbpedia-fa:Dosulepin dbpedia-sh:Dosulepin dbpedia-sr:Dosulepin dbpedia-global:Dosulepin |
| prov:wasDerivedFrom |
wikipedia-en:Dosulepin?oldid=1281010841&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Dosulepin-from-HCl-1987-xtal-CCDC-1160822.png wiki-commons:Special:FilePath/Dosulepin2DACS2.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Dosulepin |
| is dbo:wikiPageRedirects of |
dbr:Prothiaden dbr:Prothiadene dbr:Protiaden dbr:Protiadene dbr:Depresym dbr:Altapin dbr:KS-1596 dbr:KS1596 dbr:KS_1596 dbr:ATC_code_N06AA16 dbr:ATCvet_code_QN06AA16 dbr:Dopress dbr:Dosulepin_hydrochloride dbr:Dosulepina dbr:Dosulepine dbr:Dosulepinum dbr:Dosulépin dbr:Dosulépine dbr:Dothapax dbr:Dothep dbr:Dothiepin dbr:Dothiepin_hydrochloride dbr:Dothiepine dbr:IZ-914 dbr:IZ914 dbr:IZ_914 dbr:Idom dbr:Xerenal dbr:Prepadine |
| is dbo:wikiPageWikiLink of |
dbr:List_of_antidepressants dbr:Crookes_Healthcare dbr:List_of_adrenergic_drugs dbr:Tricyclic_antidepressant dbr:Antihistamine dbr:Muscarinic_antagonist dbr:Clomipramine dbr:Imipramine dbr:Dibenzothiepin dbr:Butriptyline dbr:Zotepine dbr:Trimipramine dbr:Michael_Edward_Ash dbr:NHS_treatments_blacklist dbr:ATC_code_N06 dbr:List_of_drugs:_Do dbr:Monoamine_reuptake_inhibitor dbr:Me-too_drug dbr:Doxepin dbr:Bisulepin dbr:Northiaden dbr:C19H21NS dbr:List_of_compounds_with_carbon_number_19 dbr:Pharmacology_of_antidepressants dbr:Prothiaden dbr:Prothiadene dbr:Protiaden dbr:Protiadene dbr:Depresym dbr:Altapin dbr:KS-1596 dbr:KS1596 dbr:KS_1596 dbr:ATC_code_N06AA16 dbr:ATCvet_code_QN06AA16 dbr:Dopress dbr:Dosulepin_hydrochloride dbr:Dosulepina dbr:Dosulepine dbr:Dosulepinum dbr:Dosulépin dbr:Dosulépine dbr:Dothapax dbr:Dothep dbr:Dothiepin dbr:Dothiepin_hydrochloride dbr:Dothiepine dbr:IZ-914 dbr:IZ914 dbr:IZ_914 dbr:Idom dbr:Xerenal dbr:Prepadine |
| is owl:differentFrom of |
dbr:Doxepin |
| is foaf:primaryTopic of |
wikipedia-en:Dosulepin |
