| dbo:abstract |
There are at least four known endothelin receptors, ETA, ETB1, ETB2 and ETC, all of which are G protein-coupled receptors whose activation result in elevation of intracellular-free calcium, which constricts the smooth muscles of the blood vessels, raising blood pressure, or relaxes the smooth muscles of the blood vessels, lowering blood pressure, among other functions. (en) Ci sono almeno tre recettori delle endoteline, ETA, ETB1 and ETB2, sono tutti recettori accoppiati a proteine G (GPCR) la cui attivazione provoca un aumento del calcio libero a livello intracellulare. (it) |
| dbo:arm |
q |
| dbo:band |
22 31.2 |
| dbo:chromosome |
4 13 |
| dbo:entrezgene |
1910 1909 |
| dbo:hgncid |
3180 3179 |
| dbo:omim |
131243 (xsd:integer) 131244 (xsd:integer) |
| dbo:refseq |
NM_000115 NM_001957 |
| dbo:symbol |
EDNRA EDNRB HSCR2, HSCR |
| dbo:uniprot |
P24530 P25101 |
| dbo:wikiPageExternalLink |
http://www.iuphar-db.org/GPCR/ChapterMenuForward%3FchapterID=1283 https://www.ncbi.nlm.nih.gov/pubmed/26956245 |
| dbo:wikiPageID |
5827346 (xsd:integer) |
| dbo:wikiPageLength |
6258 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1091324289 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Calcium dbr:Endothelin dbr:Endothelin_receptor_antagonist dbr:Endothelium-derived_relaxing_factor dbr:Blood_pressure dbr:Peripheral_neuropathy dbr:Choroid_plexus dbr:Stroke dbr:Neurotransmission dbr:G_protein-coupled_receptor dbr:Nitric_oxide dbr:Endothelin_receptor_type_A dbr:Endothelin_receptor_type_B dbr:Sensory_receptor dbr:Smooth_muscle dbr:ABCD_syndrome dbc:G_protein-coupled_receptors dbr:Blood_vessel dbr:Sodium dbr:Seizures dbr:Calcium_channels dbr:Waardenburg_syndrome dbr:Natriuresis dbr:Nerves dbr:Wikt:diuresis dbr:Wikt:retention |
| dbp:altsymbols |
HSCR2, HSCR (en) |
| dbp:arm |
q (en) |
| dbp:band |
22 (xsd:integer) 31.200000 (xsd:double) |
| dbp:chromosome |
4 (xsd:integer) 13 (xsd:integer) |
| dbp:entrezgene |
1909 (xsd:integer) 1910 (xsd:integer) |
| dbp:hgncid |
3179 (xsd:integer) 3180 (xsd:integer) |
| dbp:name |
dbr:Endothelin_receptor_type_A dbr:Endothelin_receptor_type_B |
| dbp:omim |
131243 (xsd:integer) 131244 (xsd:integer) |
| dbp:refseq |
NM_000115 (en) NM_001957 (en) |
| dbp:symbol |
EDNRA (en) EDNRB (en) |
| dbp:uniprot |
P24530 (en) P25101 (en) |
| dbp:wikiPageUsesTemplate |
dbt:G_protein-coupled_receptors dbt:Transmembranereceptor-stub dbt:Cite_web dbt:MeshName dbt:Reflist dbt:Short_description dbt:Protein |
| dcterms:subject |
dbc:G_protein-coupled_receptors |
| gold:hypernym |
dbr:Receptors |
| rdf:type |
owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 yago:BodyPart105220461 yago:Part109385911 yago:PhysicalEntity100001930 yago:Receptor105608868 yago:WikicatGProteinCoupledReceptors dbo:Protein yago:Structure105225602 yago:Thing100002452 umbel-rc:ProteinMolecule |
| rdfs:comment |
There are at least four known endothelin receptors, ETA, ETB1, ETB2 and ETC, all of which are G protein-coupled receptors whose activation result in elevation of intracellular-free calcium, which constricts the smooth muscles of the blood vessels, raising blood pressure, or relaxes the smooth muscles of the blood vessels, lowering blood pressure, among other functions. (en) Ci sono almeno tre recettori delle endoteline, ETA, ETB1 and ETB2, sono tutti recettori accoppiati a proteine G (GPCR) la cui attivazione provoca un aumento del calcio libero a livello intracellulare. (it) |
| rdfs:label |
Endothelin receptor (en) Recettori delle endoteline (it) |
| owl:sameAs |
freebase:Endothelin receptor yago-res:Endothelin receptor wikidata:Endothelin receptor dbpedia-fa:Endothelin receptor dbpedia-it:Endothelin receptor dbpedia-sh:Endothelin receptor dbpedia-sr:Endothelin receptor https://global.dbpedia.org/id/2Ke5k |
| prov:wasDerivedFrom |
wikipedia-en:Endothelin_receptor?oldid=1091324289&ns=0 |
| foaf:isPrimaryTopicOf |
wikipedia-en:Endothelin_receptor |
| foaf:name |
endothelin receptor type A (en) endothelin receptor type B (en) |
| is dbo:wikiPageRedirects of |
dbr:Endothelin-B_receptor dbr:Receptors,_endothelin |
| is dbo:wikiPageWikiLink of |
dbr:Quinone_methide dbr:Endothelin dbr:Endothelin_A_receptor dbr:Endothelin_B_receptor dbr:Endothelin_receptor_antagonist dbr:Rhodopsin-like_receptors dbr:Ripasudil dbr:Index_of_biochemistry_articles dbr:List_of_human_hormones dbr:Masashi_Yanagisawa dbr:Cruzipain dbr:BQ-123 dbr:BQ-788 dbr:Ambrisentan dbr:Histone_deacetylase dbr:Kendomycin dbr:Endothelin-B_receptor dbr:List_of_signaling_peptide/protein_receptor_modulators dbr:Vasoconstriction dbr:Portopulmonary_hypertension dbr:PRKCE dbr:Receptors,_endothelin |
| is foaf:primaryTopic of |
wikipedia-en:Endothelin_receptor |
