| dbo:abstract |
In molecular biology, BAR domains are highly conserved protein dimerisation domains that occur in many proteins involved in membrane dynamics in a cell. The BAR domain is banana-shaped and binds to membrane via its concave face. It is capable of sensing membrane curvature by binding preferentially to curved membranes. BAR domains are named after three proteins that they are found in: Bin, Amphiphysin and Rvs. (en) En biología molecular, un dominio BAR es un dominio de dimerización altamente conservado en proteínas, especialmente en aquellas involucradas en la dinámica de las membranas celulares. Estos dominios tienen forma de plátano y se une a la membrana a través de su cara cóncava. Es capaz de sentir la curvatura de la membrana, teniendo una preferencia de unión con las membranas curvas. Los dominios BAR reciben su nombre de tres proteínas en las que se encuentran: Bin, Anfifisina y Rvs. (es) BAR结构域（英語：BAR domain）在分子生物学中是在细胞中参与膜动力学的许多蛋白质中出现的高度保守的蛋白质二聚化结构域。BAR结构域是香蕉形的，并且通过其凹面与膜结合。它能够通过优先结合弯曲的膜来感测膜弯曲。BAR结构域的命名是以它们被所发现的三种蛋白命名：Bin，Amphiphysin和Rvs。 (zh) |
| dbo:symbol |
BAR BAR-2 BAR-3 BAR-3-WASP FCH Vps5 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/PDB_1uru_EBI.jpg?width=300 |
| dbo:wikiPageExternalLink |
http://dev.biologists.org/cgi/pmidlookup%3Fview=long&pmid=11748137 https://web.archive.org/web/20130727122243/http:/www.endocytosis.org/BARdomains/BARs.html |
| dbo:wikiPageID |
6910868 (xsd:integer) |
| dbo:wikiPageLength |
8610 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1037504449 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Amphiphysin dbr:BIN1 dbr:Membrane_curvature dbr:SH3GL1 dbr:SNX9 dbr:Arfaptin dbr:Development_(journal) dbr:Dynamin dbr:SH3GLB1 dbr:Epsin dbr:Traffic_(journal) dbc:Peripheral_membrane_proteins dbc:Protein_domains dbr:J._Neurosci. dbr:ARHGAP44 dbr:IMD_domain dbr:SH3GL3 dbr:Sorting_nexin dbr:Muniscins dbr:SH3BP1 dbr:SH3GL2 dbr:SNX1 dbr:PX_domain dbr:SH3GLB2 dbr:SH3_domain dbr:SNX8 dbr:BIN3 dbr:GMIP dbr:AMPH dbr:ARHGAP17 dbr:BIN2 dbr:DNMBP dbr:RICH2 |
| dbp:caption |
Structure of amphiphysin BAR. (en) found in SNX1, SNX2, SNX4, SNX7, SNX8, and SNX30 (en) |
| dbp:cdd |
cd07307 (en) |
| dbp:interpro |
IPR004148 (en) IPR015404 (en) |
| dbp:name |
BAR domain (en) BAR domain of APPL family (en) Bin/amphiphysin/Rvs domain (en) EFC/F-BAR homology domain (en) Vps5 C terminal like (en) WASP-binding domain of sorting nexin proteins (en) |
| dbp:pfam |
PF00611 (en) PF03114 (en) PF09325 (en) PF10455 (en) PF10456 (en) PF16746 (en) |
| dbp:prosite |
PDOC51021 (en) |
| dbp:scop |
1 (xsd:integer) |
| dbp:smart |
SM00721 (en) |
| dbp:symbol |
FCH (en) BAR (en) BAR-2 (en) BAR-3 (en) BAR-3-WASP (en) Vps5 (en) |
| dbp:wikiPageUsesTemplate |
dbt:Sorting_nexins dbt:Anchor dbt:Cite_journal dbt:Infobox_protein_family dbt:Reflist dbt:Short_description dbt:Protein_domains dbt:Pfam_box |
| dcterms:subject |
dbc:Peripheral_membrane_proteins dbc:Protein_domains |
| rdf:type |
owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 yago:Abstraction100002137 yago:Family108078020 yago:Group100031264 yago:Organization108008335 yago:YagoLegalActor yago:YagoLegalActorGeo yago:YagoPermanentlyLocatedEntity dbo:Protein yago:SocialGroup107950920 yago:Unit108189659 |
| rdfs:comment |
In molecular biology, BAR domains are highly conserved protein dimerisation domains that occur in many proteins involved in membrane dynamics in a cell. The BAR domain is banana-shaped and binds to membrane via its concave face. It is capable of sensing membrane curvature by binding preferentially to curved membranes. BAR domains are named after three proteins that they are found in: Bin, Amphiphysin and Rvs. (en) En biología molecular, un dominio BAR es un dominio de dimerización altamente conservado en proteínas, especialmente en aquellas involucradas en la dinámica de las membranas celulares. Estos dominios tienen forma de plátano y se une a la membrana a través de su cara cóncava. Es capaz de sentir la curvatura de la membrana, teniendo una preferencia de unión con las membranas curvas. Los dominios BAR reciben su nombre de tres proteínas en las que se encuentran: Bin, Anfifisina y Rvs. (es) BAR结构域（英語：BAR domain）在分子生物学中是在细胞中参与膜动力学的许多蛋白质中出现的高度保守的蛋白质二聚化结构域。BAR结构域是香蕉形的，并且通过其凹面与膜结合。它能够通过优先结合弯曲的膜来感测膜弯曲。BAR结构域的命名是以它们被所发现的三种蛋白命名：Bin，Amphiphysin和Rvs。 (zh) |
| rdfs:label |
BAR domain (en) Dominio BAR (es) BAR结构域 (zh) |
| owl:sameAs |
freebase:BAR domain wikidata:BAR domain dbpedia-es:BAR domain dbpedia-sh:BAR domain dbpedia-sr:BAR domain dbpedia-zh:BAR domain https://global.dbpedia.org/id/2LGg3 |
| prov:wasDerivedFrom |
wikipedia-en:BAR_domain?oldid=1037504449&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/PDB_1uru_EBI.jpg |
| foaf:isPrimaryTopicOf |
wikipedia-en:BAR_domain |
| is dbo:wikiPageDisambiguates of |
dbr:Bar |
| is dbo:wikiPageRedirects of |
dbr:Bar_domain dbr:Syndapin dbr:Bin-Amphiphysin-RVS dbr:F-BAR_domain |
| is dbo:wikiPageWikiLink of |
dbr:Amphiphysin dbr:Membrane_curvature dbr:L._C._Dunn dbr:SH3GLB1 dbr:Fluid_mosaic_model dbr:Receptor-mediated_endocytosis dbr:APPL1 dbr:ARHGAP26 dbr:Bar dbr:Bar_domain dbr:Bulk_endocytosis dbr:Bridging_integrator_3 dbr:IMD_domain dbr:Sorting_nexin dbr:Muniscins dbr:SNX8 dbr:Syndapin dbr:Bin-Amphiphysin-RVS dbr:F-BAR_domain |
| is foaf:primaryTopic of |
wikipedia-en:BAR_domain |
