Free water clearance (original) (raw)
In the physiology of the kidney, free water clearance (CH2O) is the volume of blood plasma that is cleared of solute-free water per unit time. An example of its use is in the determination of an individual's state of hydration. Conceptually, free water clearance should be thought of relative to the production of , which would be equal to the osmolarity of the plasma. If an individual is producing urine more dilute than the plasma, there is a positive value for free water clearance, meaning pure water is lost in the urine in addition to a theoretical isoosmotic filtrate. If the urine is more concentrated than the plasma, then free water is being extracted from the urine, giving a negative value for free water clearance. A negative value is typical for free water clearance, as the kidney usu
| Property | Value |
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| dbo:abstract | In the physiology of the kidney, free water clearance (CH2O) is the volume of blood plasma that is cleared of solute-free water per unit time. An example of its use is in the determination of an individual's state of hydration. Conceptually, free water clearance should be thought of relative to the production of , which would be equal to the osmolarity of the plasma. If an individual is producing urine more dilute than the plasma, there is a positive value for free water clearance, meaning pure water is lost in the urine in addition to a theoretical isoosmotic filtrate. If the urine is more concentrated than the plasma, then free water is being extracted from the urine, giving a negative value for free water clearance. A negative value is typical for free water clearance, as the kidney usually produces concentrated urine except in the cases of volume overload by the individual. (en) |
| dbo:wikiPageExternalLink | https://web.archive.org/web/20060927080625/http:/sprojects.mmi.mcgill.ca/nephrology/resources/freewater.asp https://web.archive.org/web/20070101211250/http:/sprojects.mmi.mcgill.ca/nephrology/presentation/Final%20Notes%20Concentration%20and%20Dilution.htm https://web.archive.org/web/20070715122822/http:/www.lib.mcg.edu/edu/eshuphysio/program/section7/7ch08/7ch08p21.htm |
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| dbo:wikiPageWikiLink | dbr:Blood_plasma dbr:Plasma_osmolality dbr:Renal_physiology dbr:Solute dbr:Kidney dbc:Renal_physiology dbr:Urine dbr:Water dbr:Urine_osmolality dbr:Osmolarity dbr:Renal_clearance dbr:Antidiuretic_hormone dbr:Isoosmotic_urine |
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| rdfs:comment | In the physiology of the kidney, free water clearance (CH2O) is the volume of blood plasma that is cleared of solute-free water per unit time. An example of its use is in the determination of an individual's state of hydration. Conceptually, free water clearance should be thought of relative to the production of , which would be equal to the osmolarity of the plasma. If an individual is producing urine more dilute than the plasma, there is a positive value for free water clearance, meaning pure water is lost in the urine in addition to a theoretical isoosmotic filtrate. If the urine is more concentrated than the plasma, then free water is being extracted from the urine, giving a negative value for free water clearance. A negative value is typical for free water clearance, as the kidney usu (en) |
| rdfs:label | Free water clearance (en) |
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