| dbo:abstract |
Galactose oxidase (D-galactose:oxygen 6-oxidoreductase, D-galactose oxidase, beta-galactose oxidase; abbreviated GAO, GAOX, GOase; EC 1.1.3.9) is an enzyme that catalyzes the oxidation of D-galactose in some species of fungi. Galactose oxidase belongs to the family of oxidoreductases. Copper ion is required as a cofactor for galactose oxidase. A remarkable feature of galactose oxidase is that it is a free radical enzyme. Its catalytic site contains a free radical ligand coordinating to the copper center. This free radical ligand is a covalently cross-linked cysteine and tyrosine side chains that is formed during post-translational modification. (en) La galattosio ossidasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: D-galattosio + O2 ⇄ D-galatto- + H2O2 L'enzima utilizza il rame come cofattore. (it) ガラクトースオキシダーゼ（galactose oxidase）は、次の化学反応を触媒する酸化還元酵素である。 D-ガラクトース + O2 D-ガラクトヘキソジアルドース + H2O2 すなわち、この酵素の基質はD-ガラクトースとO2、生成物はD-とH2O2である。補因子として銅と、翻訳後修飾から誘導されるCys228およびTyr272の共有結合性架橋結合を含むアミノ酸活性部位が用いられる。 組織名はD-galactose:oxygen 6-oxidoreductaseで、別名にD-galactose oxidase, β-galactose oxidaseがある。 (ja) |
| dbo:ecNumber |
1.1.3.9 |
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wiki-commons:Special:FilePath/1gog.jpg?width=300 |
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| dbo:wikiPageWikiLink |
dbr:Carboxylic_acids dbr:Electron_density dbr:Electron_paramagnetic_resonance dbr:Mutation dbr:Coordinate_bond dbr:Biocatalyst dbr:Antiferromagnetism dbr:Hydrogen_peroxide dbr:Beta-sandwich dbr:Beta_sheet dbr:Peptide dbr:Reaction_intermediate dbc:EC_1.1.3 dbc:Enzymes_of_known_structure dbr:Enzyme dbr:Fungi dbr:Fusarium dbr:Genera dbr:Glycoproteins dbr:Coordination_geometry dbr:Coordination_sphere dbr:Copper_protein dbr:Regioselective dbr:Ligand dbr:Colorimetric_analysis dbr:Computational_chemistry dbr:Fusarium_graminearum dbr:Post-translational_modification dbr:Tryptophan dbr:Tyrosine dbr:Catalytic_site dbr:Leader_sequence_(mRNA) dbr:Protein_quaternary_structure dbr:Alcohol_(chemistry) dbr:Aldehydes dbr:Amino_acids dbr:Cysteine dbr:Dimer_(chemistry) dbr:Protein_domain dbr:Rate-determining_step dbc:Copper_enzymes dbr:Histidine dbr:Bacteriostatic_agent dbr:Aldehyde dbr:Superoxide dbr:Cofactor_(biochemistry) dbr:Dihydroxyacetone dbr:Aspergillus dbr:Free_radical dbr:Hydrophobic dbr:D-galactose dbr:Imidazole dbr:Indole dbr:X-ray_crystallography dbr:Hydroxyl dbr:Thioether dbr:Oxidation dbr:Oxidoreductases dbr:Dioxygen dbr:Protein_precursor dbr:Signal_peptidase dbr:Prochirality dbr:Stereospecific dbr:Thiyl_radical dbr:Proteolytic_cleavage dbr:Phenoxide dbr:Phenoxyl dbr:Hydrogen_bonding dbr:Aromatic_ring dbr:Chelating_ligand dbr:Labile dbr:Delocalization dbr:Histidines dbr:Oxidation_potential dbr:Tyrosines dbr:D-galacto-hexodialdose dbr:Duncamine dbr:File:Active_site_of_Galactose_Oxidase.jpg dbr:File:Mechanism_of_Galactose_Oxidase.jpg dbr:File:The_redox_scheme_and_the_oxidation_states_of_galactose_oxidase.png |
| dbp:caption |
Crystal structure of galactose oxidase showing three domains: Domain 1 , Domain 2 , and Domain 3 (en) |
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9028 (xsd:integer) |
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1.100000 (xsd:double) |
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| dbp:iubmbEcNumber |
1 (xsd:integer) |
| dbp:name |
Galactose Oxidase (en) |
| dbp:wikiPageUsesTemplate |
dbt:Alcohol_oxidoreductases dbt:EC_number dbt:Enzyme dbt:Enzymes dbt:Portal_bar dbt:Reflist |
| dcterms:subject |
dbc:EC_1.1.3 dbc:Enzymes_of_known_structure dbc:Copper_enzymes |
| gold:hypernym |
dbr:Enzyme |
| rdf:type |
owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8047 yago:WikicatCopperEnzymes yago:Abstraction100002137 yago:Activator114723079 yago:Catalyst114723628 yago:Chemical114806838 yago:Compound114818238 yago:Enzyme114732946 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Enzyme dbo:Protein yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatEnzymesOfKnownStructure |
| rdfs:comment |
La galattosio ossidasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: D-galattosio + O2 ⇄ D-galatto- + H2O2 L'enzima utilizza il rame come cofattore. (it) ガラクトースオキシダーゼ（galactose oxidase）は、次の化学反応を触媒する酸化還元酵素である。 D-ガラクトース + O2 D-ガラクトヘキソジアルドース + H2O2 すなわち、この酵素の基質はD-ガラクトースとO2、生成物はD-とH2O2である。補因子として銅と、翻訳後修飾から誘導されるCys228およびTyr272の共有結合性架橋結合を含むアミノ酸活性部位が用いられる。 組織名はD-galactose:oxygen 6-oxidoreductaseで、別名にD-galactose oxidase, β-galactose oxidaseがある。 (ja) Galactose oxidase (D-galactose:oxygen 6-oxidoreductase, D-galactose oxidase, beta-galactose oxidase; abbreviated GAO, GAOX, GOase; EC 1.1.3.9) is an enzyme that catalyzes the oxidation of D-galactose in some species of fungi. (en) |
| rdfs:label |
Galactose oxidase (en) Galattosio ossidasi (it) ガラクトースオキシダーゼ (ja) |
| owl:sameAs |
freebase:Galactose oxidase yago-res:Galactose oxidase http://www4.wiwiss.fu-berlin.de/drugbank/resource/targets/2582 wikidata:Galactose oxidase dbpedia-it:Galactose oxidase dbpedia-ja:Galactose oxidase dbpedia-sh:Galactose oxidase dbpedia-sr:Galactose oxidase https://global.dbpedia.org/id/2bBUc |
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wikipedia-en:Galactose_oxidase?oldid=1064283623&ns=0 |
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wiki-commons:Special:FilePath/1gog.jpg wiki-commons:Special:FilePath/Active_site_of_Galactose_Oxidase.jpg wiki-commons:Special:FilePath/Mechanism_of_Galactose_Oxidase.jpg wiki-commons:Special:FilePath/The_redox_scheme_and_...ation_states_of_galactose_oxidase.png |
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wikipedia-en:Galactose_oxidase |
| foaf:name |
Galactose Oxidase (en) |
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dbr:Kelch_motif dbr:List_of_EC_numbers_(EC_1) dbr:List_of_MeSH_codes_(D08) dbr:Karl_Wieghardt dbr:D-galactose:oxygen_6-oxidoreductase dbr:Multiple_Epidermal_Growth_Factor-like_Domains_8 dbr:EC_1.1.3.9 |
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