| dbo:abstract |
Glycylcycline stellen eine Antibiotikaklasse dar, die sich von Tetracyclinen ableitet. Glycylcycline wurden entwickelt, um typische Mechanismen der Antibiotikaresistenz gegenüber Tetracyclinen zu überwinden. Dies betrifft einerseits bakterielle Effluxpumpen, aber auch ribosomale Ansatzpunkte. Gegenwärtig ist Tigecyclin der einzige zugelassene Vertreter dieser Wirkstoffgruppe. (de) Glycylcyclines are a class of antibiotics derived from tetracycline. These tetracycline analogues are specifically designed to overcome two common mechanisms of tetracycline resistance, namely resistance mediated by acquired efflux pumps and/or ribosomal protection. Presently, tigecycline is the only glycylcycline approved for antibiotic use. (en) As glicilciclinas são uma nova classe de antibióticos sem casos de resistência bacteriana. O único membro desses antibióticos derivados das tetraciclinas é a tigeciclina. (pt) |
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http://www.formularyjournal.com/formulary/article/articleDetail.jsp%3Fid=177008 http://www.rxlist.com/tygacil-side-effects-drug-center.htm https://web.archive.org/web/20070928204927/http:/www.formularyjournal.com/formulary/article/articleDetail.jsp%3Fid=177008 https://web.archive.org/web/20080706124941/http:/www.tygacil.com/ |
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| dbo:wikiPageWikiLink |
dbr:Pseudomonas dbr:Minocycline dbc:Glycylcycline_antibiotics dbr:Tigecycline dbr:Tetracycline dbr:Efflux_(microbiology) dbr:Mechanism_of_action dbr:Ribosome dbr:Photosensitivity dbr:Side_chain dbr:Tooth_discoloration dbr:Chromosomal_efflux_pump |
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dbt:Cite_journal dbt:Reflist dbt:TetracyclineAntiBiotics |
| dcterms:subject |
dbc:Glycylcycline_antibiotics |
| gold:hypernym |
dbr:Class |
| rdf:type |
yago:Agent114778436 yago:Antibacterial102716205 yago:Antibiotic102716866 yago:CausalAgent100007347 yago:Drug103247620 yago:Matter100020827 yago:Medicine103740161 yago:PhysicalEntity100001930 yago:WikicatGlycylcyclineAntibiotics yago:Substance100020090 |
| rdfs:comment |
Glycylcycline stellen eine Antibiotikaklasse dar, die sich von Tetracyclinen ableitet. Glycylcycline wurden entwickelt, um typische Mechanismen der Antibiotikaresistenz gegenüber Tetracyclinen zu überwinden. Dies betrifft einerseits bakterielle Effluxpumpen, aber auch ribosomale Ansatzpunkte. Gegenwärtig ist Tigecyclin der einzige zugelassene Vertreter dieser Wirkstoffgruppe. (de) Glycylcyclines are a class of antibiotics derived from tetracycline. These tetracycline analogues are specifically designed to overcome two common mechanisms of tetracycline resistance, namely resistance mediated by acquired efflux pumps and/or ribosomal protection. Presently, tigecycline is the only glycylcycline approved for antibiotic use. (en) As glicilciclinas são uma nova classe de antibióticos sem casos de resistência bacteriana. O único membro desses antibióticos derivados das tetraciclinas é a tigeciclina. (pt) |
| rdfs:label |
Glycylcycline (de) Glycylcycline (en) Glicilciclinas (pt) |
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freebase:Glycylcycline yago-res:Glycylcycline wikidata:Glycylcycline dbpedia-de:Glycylcycline dbpedia-pt:Glycylcycline dbpedia-sh:Glycylcycline dbpedia-sr:Glycylcycline https://global.dbpedia.org/id/4kGMj |
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wikipedia-en:Glycylcycline |
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