Hippulin (original) (raw)
Hippulin, also known as Δ8-14-isoestrone, as well as 14-isoestra-1,3,5(10),8-tetraen-3-ol-17-one, is a naturally occurring estrogen found in horses and an isomer of equilin. The compound, likely in sodium sulfate form, is a component of conjugated estrogens (Premarin), a pharmaceutical extract of the urine of pregnant mares, though it is present only in small amounts in pregnant mare urine. It has been reported by possess either equivalent estrogenic activity to that of equilin or only slight estrogenic activity. The compound was first described in 1932.
| Property | Value |
|---|---|
| dbo:abstract | Hippulin, also known as Δ8-14-isoestrone, as well as 14-isoestra-1,3,5(10),8-tetraen-3-ol-17-one, is a naturally occurring estrogen found in horses and an isomer of equilin. The compound, likely in sodium sulfate form, is a component of conjugated estrogens (Premarin), a pharmaceutical extract of the urine of pregnant mares, though it is present only in small amounts in pregnant mare urine. It has been reported by possess either equivalent estrogenic activity to that of equilin or only slight estrogenic activity. The compound was first described in 1932. (en) 8,9-脱氢雌酮（英語：8,9-Dehydroestrone，Δ8-estrone）也称为异马烯雌酮（英語：isoequilin）是一种存在于马中的天然雌激素，半系统名：雌甾-1,3,5(10),8-四烯-3-醇-17-酮，estra-1,3,5(10),8-tetraen-3-ol-17-one。8,9-脱氢雌酮的3-硫酸酯是結合型雌激素（普立马）的成分之一，约占3.5%。8,9-脱氢雌酮在体内可转化成，过程类似于雌酮转化成雌二醇。 (zh) |
| dbo:casNumber | 474-87-3 |
| dbo:class | dbr:Estrogen_(medication) |
| dbo:fdaUniiCode | 7C1N8RKG9F |
| dbo:pubchem | 6451472 |
| dbo:thumbnail | wiki-commons:Special:FilePath/Hippulin.svg?width=300 |
| dbo:wikiPageID | 54237945 (xsd:integer) |
| dbo:wikiPageLength | 4128 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1100269792 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Pregnancy dbr:List_of_estrogens dbr:Pharmaceutical_drug dbc:Estranes dbc:Estrogens dbc:Ketones dbc:Phenols dbr:Conjugated_estrogens dbr:Estrogen_(medication) dbr:Natural_product dbr:Oral_administration dbr:Equilin dbr:Equine dbr:Isomer dbr:Sulfate dbr:Sodium dbr:Mare dbr:Urine dbr:Extract |
| dbp:c | 18 (xsd:integer) |
| dbp:casNumber | 474 (xsd:integer) |
| dbp:chemspiderid | 4953937 (xsd:integer) |
| dbp:class | dbr:Estrogen_(medication) |
| dbp:h | 20 (xsd:integer) |
| dbp:iupacName | -3 (xsd:integer) |
| dbp:o | 2 (xsd:integer) |
| dbp:pubchem | 6451472 (xsd:integer) |
| dbp:routesOfAdministration | dbr:Oral_administration |
| dbp:smiles | C[C@]12CCC3=CCCc4c3cccO (en) |
| dbp:stdinchi | 1 (xsd:integer) |
| dbp:stdinchikey | OUGSRCWSHMWPQE-WMZOPIPTSA-N (en) |
| dbp:synonyms | Δ8-14-Isoestrone; 8-Dehydro-14-isoestrone; 14-Isoestra-1,3,5,8-tetraen-3-ol-17-one (en) |
| dbp:unii | 7 (xsd:integer) |
| dbp:width | 225 (xsd:integer) |
| dbp:wikiPageUsesTemplate | dbt:Drugbox dbt:Estrogen_receptor_modulators dbt:Genito-urinary-drug-stub dbt:Reflist dbt:Short_description dbt:Steroid-stub dbt:Cascite dbt:Fdacite dbt:Estrogens_and_antiestrogens |
| dcterms:subject | dbc:Estranes dbc:Estrogens dbc:Ketones dbc:Phenols |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug |
| rdfs:comment | Hippulin, also known as Δ8-14-isoestrone, as well as 14-isoestra-1,3,5(10),8-tetraen-3-ol-17-one, is a naturally occurring estrogen found in horses and an isomer of equilin. The compound, likely in sodium sulfate form, is a component of conjugated estrogens (Premarin), a pharmaceutical extract of the urine of pregnant mares, though it is present only in small amounts in pregnant mare urine. It has been reported by possess either equivalent estrogenic activity to that of equilin or only slight estrogenic activity. The compound was first described in 1932. (en) 8,9-脱氢雌酮（英語：8,9-Dehydroestrone，Δ8-estrone）也称为异马烯雌酮（英語：isoequilin）是一种存在于马中的天然雌激素，半系统名：雌甾-1,3,5(10),8-四烯-3-醇-17-酮，estra-1,3,5(10),8-tetraen-3-ol-17-one。8,9-脱氢雌酮的3-硫酸酯是結合型雌激素（普立马）的成分之一，约占3.5%。8,9-脱氢雌酮在体内可转化成，过程类似于雌酮转化成雌二醇。 (zh) |
| rdfs:label | Hippulin (en) 8,9-脱氢雌酮 (zh) |
| owl:sameAs | wikidata:Hippulin wikidata:Hippulin dbpedia-zh:Hippulin https://global.dbpedia.org/id/2YUVt |
| prov:wasDerivedFrom | wikipedia-en:Hippulin?oldid=1100269792&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Hippulin.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:Hippulin |
| is dbo:wikiPageRedirects of | dbr:8-Dehydro-14-isoestrone dbr:8-dehydro-14-isoestrone dbr:Hippulin_sulfate dbr:Hippuline |
| is dbo:wikiPageWikiLink of | dbr:List_of_estrogens dbr:C18H20O2 dbr:Equine_estrogen dbr:8-Dehydro-14-isoestrone dbr:8-dehydro-14-isoestrone dbr:Hippulin_sulfate dbr:Hippuline |
| is foaf:primaryTopic of | wikipedia-en:Hippulin |
