Histamine dihydrochloride (original) (raw)
Histamine dihydrochloride (INN, trade name Ceplene) is a salt of histamine that is used as a drug for the prevention of relapse in patients diagnosed with acute myeloid leukemia (AML). It is also an FDA-approved active ingredient for topical analgesic use for the temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, bruises, sprains, and strains and is available in over-the-counter (OTC) products such as Australian Dream and Golden Creme.
| Property | Value |
|---|---|
| dbo:abstract | Histamine dihydrochloride (INN, trade name Ceplene) is a salt of histamine that is used as a drug for the prevention of relapse in patients diagnosed with acute myeloid leukemia (AML). It is also an FDA-approved active ingredient for topical analgesic use for the temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, bruises, sprains, and strains and is available in over-the-counter (OTC) products such as Australian Dream and Golden Creme. (en) Ceplene (histamindihydroklorid) är ett immunstimulerande läkemedel som används vid behandling av akut myeloisk leukemi (AML), en form av blodcancer. Ceplene, som utvecklats av en forskargrupp vid Göteborgs universitet, godkändes 2008 för försäljning i Europa av läkemedelsmyndigheten EMA och av EU-kommissionen. Ceplene blev därmed det första svenskutvecklade originalläkemedel som godkänts i Europa på mer än ett decennium. (sv) |
| dbo:alternativeName | Ceplene (en) |
| dbo:casNumber | 56-92-8 |
| dbo:fdaUniiCode | 3POA0Q644U |
| dbo:pubchem | 11309913 |
| dbo:thumbnail | wiki-commons:Special:FilePath/Histamine_2HCl_skeletal.svg?width=300 |
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| dbp:casNumber | 56 (xsd:integer) |
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| dbp:cl | 2 (xsd:integer) |
| dbp:h | 11 (xsd:integer) |
| dbp:iupacName | 2 (xsd:integer) |
| dbp:legalStatus | Approved for use in the EU and Israel (en) |
| dbp:licenceEu | yes (en) |
| dbp:n | 3 (xsd:integer) |
| dbp:pubchem | 11309913 (xsd:integer) |
| dbp:routesOfAdministration | dbr:Subcutaneous_injection dbr:Topical |
| dbp:smiles | C1=CCCN.Cl.Cl (en) |
| dbp:stdinchi | 1 (xsd:integer) |
| dbp:stdinchikey | PPZMYIBUHIPZOS-UHFFFAOYSA-N (en) |
| dbp:tradename | Ceplene (en) |
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| gold:hypernym | dbr:Salt |
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| rdfs:comment | Histamine dihydrochloride (INN, trade name Ceplene) is a salt of histamine that is used as a drug for the prevention of relapse in patients diagnosed with acute myeloid leukemia (AML). It is also an FDA-approved active ingredient for topical analgesic use for the temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, bruises, sprains, and strains and is available in over-the-counter (OTC) products such as Australian Dream and Golden Creme. (en) Ceplene (histamindihydroklorid) är ett immunstimulerande läkemedel som används vid behandling av akut myeloisk leukemi (AML), en form av blodcancer. Ceplene, som utvecklats av en forskargrupp vid Göteborgs universitet, godkändes 2008 för försäljning i Europa av läkemedelsmyndigheten EMA och av EU-kommissionen. Ceplene blev därmed det första svenskutvecklade originalläkemedel som godkänts i Europa på mer än ett decennium. (sv) |
| rdfs:label | Histamine dihydrochloride (en) Ceplene (sv) |
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