| dbo:abstract |
Hydrophobins are a group of small (~100 amino acids) cysteine-rich proteins that are expressed only by filamentous fungi that are lichenized or not. They are known for their ability to form a hydrophobic (water-repellent) coating on the surface of an object. They were first discovered and separated in Schizophyllum commune in 1991. Based on differences in hydropathy patterns and biophysical properties, they can be divided into two categories: class I and class II. Hydrophobins can self-assemble into a monolayer on hydrophilic:hydrophobic interfaces such as a water:air interface. Class I monolayer contains the same core structure as amyloid fibrils, and is positive to Congo red and thioflavin T. The monolayer formed by class I hydrophobins has a highly ordered structure, and can only be dissociated by concentrated trifluoroacetate or formic acid. Monolayer assembly involves large structural rearrangements with respect to the monomer. Fungi make complex aerial structures and spores even in aqueous environments. Hydrophobins have been identified in lichens as well as non-lichenized ascomycetes and basidiomycetes; whether they exist in other groups is not known. Hydrophobins are generally found on the outer surface of conidia and of the hyphal wall, and may be involved in mediating contact and communication between the fungus and its environment. Some family members contain multiple copies of the domain. Hydrophobins have been found to be structurally and functionally similar to cerato-platanins, another group of small cysteine-rich proteins, which also contain a high percentage of hydrophobic amino acids, and are also associated with hyphal growth. This family of proteins includes the rodlet proteins of Neurospora crassa (gene eas) and Emericella nidulans (gene rodA), these proteins are the main component of the hydrophobic sheath covering the surface of many fungal spores. Genomic sequencing of two fungi from dry or salty environments (Wallemia sebi and W. ichthyophaga) revealed that these species contain predicted hydrophobins with unusually high proportion of acidic amino acids and therefore with potentially novel characteristics. High proportion of acidic amino acids is thought to be an adaptation of proteins to high concentrations of salt. (en) As hidrofobinas são um grupo de pequenas proteínas ricas em cisteína (com aproximadamente 100 aminoácidos) que são expressas apenas por fungos filamentosos. São conhecidas pela sua capacidade para formarem um revestimento hidrofóbico na superfície de um objecto. Foram descobertas pela primeira vez em em 1991. Com base em diferenças nos padrões de e propriedades biofísicas, dividem-se em duas categorias: classe I e classe II. Foram identificadas em ascomicetes e basidiomicetes; não se sabe se existem noutros grupos. São geralmente encontradas na superfície exterior dos conídios e da parede das hifas, e podem estar ligadas à mediação de contacto e comunicação dos fungos com o seu ambiente. (pt) |
| dbo:symbol |
Hydrophobin Hydrophobin_2 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Hydrophobin.png?width=300 |
| dbo:wikiPageExternalLink |
http://irs.ub.rug.nl/ppn/240088549 |
| dbo:wikiPageID |
7627201 (xsd:integer) |
| dbo:wikiPageLength |
26394 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1041855981 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Proteins dbr:Biocompatibility dbr:Hydropathy dbr:Hypha dbr:Carbon_nanotubes dbr:NMR_spectroscopy dbc:Protein_families dbr:Congo_red dbr:Protein_purification dbr:Fungi dbr:Mold_(fungus) dbr:Conidium dbr:Lichen dbr:Amphipathic dbr:Amyloids dbr:Wallemia_ichthyophaga dbc:Proteins dbr:Wallemia_sebi dbr:Drug_delivery dbr:Amino_acid dbr:Cysteine dbr:Protein_family dbr:Protein dbr:Hydrophobe dbr:Atomic-force_microscopy dbr:Biophysics dbr:X-ray_diffraction dbr:Aspergillus_nidulans dbr:Spores dbr:Emulsifiers dbr:H-bonding dbr:Cerato-platanin dbr:RodA dbr:Neurospora_crassa dbr:Schizophyllum_commune dbr:Trichoderma_reesei dbr:Site-directed_mutagenesis dbr:Β-sheet dbr:Ascomycetes dbr:Basidiomycetes dbr:Emericella_nidulans dbr:Fungal_spore dbr:Targeted_mutagenesis dbr:Thioflavin_T dbr:EAS_(hydrophobin) |
| dbp:caption |
Structure of hydrophobin HFBII from Trichoderma reesei (en) |
| dbp:interpro |
IPR001338 (en) IPR010636 (en) |
| dbp:name |
Fungal hydrophobin (en) Hydrophobin (en) |
| dbp:opmFamily |
96 (xsd:integer) |
| dbp:opmProtein |
120.0 |
| dbp:pfam |
PF01185 (en) PF06766 (en) |
| dbp:prosite |
PDOC00739 (en) |
| dbp:scop |
120.0 |
| dbp:symbol |
Hydrophobin (en) Hydrophobin_2 (en) |
| dbp:uniprot |
P79073 (en) |
| dbp:width |
250 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Cite_journal dbt:Cite_thesis dbt:Infobox_protein_family dbt:InterPro_content dbt:Refbegin dbt:Refend dbt:Reflist dbt:Pfam_box |
| dcterms:subject |
dbc:Protein_families dbc:Proteins |
| gold:hypernym |
dbr:Group |
| rdf:type |
owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 yago:Abstraction100002137 yago:Family108078020 yago:Group100031264 yago:Organization108008335 yago:YagoLegalActor yago:YagoLegalActorGeo yago:YagoPermanentlyLocatedEntity dbo:Band dbo:Protein yago:SocialGroup107950920 yago:Unit108189659 yago:WikicatProteinFamilies |
| rdfs:comment |
Hydrophobins are a group of small (~100 amino acids) cysteine-rich proteins that are expressed only by filamentous fungi that are lichenized or not. They are known for their ability to form a hydrophobic (water-repellent) coating on the surface of an object. They were first discovered and separated in Schizophyllum commune in 1991. Based on differences in hydropathy patterns and biophysical properties, they can be divided into two categories: class I and class II. Hydrophobins can self-assemble into a monolayer on hydrophilic:hydrophobic interfaces such as a water:air interface. Class I monolayer contains the same core structure as amyloid fibrils, and is positive to Congo red and thioflavin T. The monolayer formed by class I hydrophobins has a highly ordered structure, and can only be dis (en) As hidrofobinas são um grupo de pequenas proteínas ricas em cisteína (com aproximadamente 100 aminoácidos) que são expressas apenas por fungos filamentosos. São conhecidas pela sua capacidade para formarem um revestimento hidrofóbico na superfície de um objecto. Foram descobertas pela primeira vez em em 1991. Com base em diferenças nos padrões de e propriedades biofísicas, dividem-se em duas categorias: classe I e classe II. (pt) |
| rdfs:label |
Hydrophobin (en) Hidrofobina (pt) |
| owl:sameAs |
freebase:Hydrophobin yago-res:Hydrophobin wikidata:Hydrophobin dbpedia-pt:Hydrophobin https://global.dbpedia.org/id/2LEN1 |
| prov:wasDerivedFrom |
wikipedia-en:Hydrophobin?oldid=1041855981&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Hydrophobin.png |
| foaf:isPrimaryTopicOf |
wikipedia-en:Hydrophobin |
| is dbo:wikiPageRedirects of |
dbr:Hydrophobins |
| is dbo:wikiPageWikiLink of |
dbr:Candelaria_concolor dbr:Hypha dbr:Amyloid dbr:Fungus dbr:Spore dbr:Wallemia_ichthyophaga dbr:Aeroallergen dbr:Hydrophobins dbr:Cerato-platanin dbr:RodA dbr:Schizophyllum_commune |
| is foaf:primaryTopic of |
wikipedia-en:Hydrophobin |
