Iloprost (original) (raw)

dbo:abstract

إيلوبروست (Iloprost) تركيبه الكيميائي إلوبروست تروميثامين، ، ويؤثر على تراكم الصفائح الدموية. (ar)
Iloprost is a medication used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and other diseases in which the blood vessels are constricted and blood cannot flow to the tissues. This damages the tissues and causes high blood pressure. There is ongoing research into using it as a frostbite treatment. Iloprost works by opening (dilating) the blood vessels to allow the blood to flow through again. It was developed by the pharmaceutical company Schering AG and is marketed by Bayer Schering Pharma AG in Europe and Actelion Pharmaceuticals in the USA. Iloprost is given via inhalation, and a therapeautic benefit of the drug is that a very low dose is required because of the deposition in the lung. Iloprost has few systemic side effects for that reason. (en)
El iloprost es un análogo sintético de la prostaciclina administrado por vía inhalada para mejorar los síntomas hemodinámicos de la hipertensión pulmonar. Se ha estudiado para el uso preventivo de lesiones por reperfusión. Otros análogos de la prostaciclina son administrados por vía subcutánea (treprostinil) u oral (beraprost). (es)
L'iloprost est une molécule analogue de la prostacycline, développé par Actelion, utilisé comme médicament administré par inhalation dans l'hypertension artérielle pulmonaire de classe III ou IV. (fr)
Iloprost adalah obat golongan analog prostasiklin yang digunakan untuk mengobati hipertensi paru. Iloprost bekerja dengan cara relaksasi otot polos pembuluh darah dan menyebabkan vasodilatasi. Penggunaan jangka panjangnya akan mempengaruhi tahanan vaskular pembuluh darah dan menekan proliferasi otot polos pembuluh darah. Iloprost juga memiliki efek inhibitor agregasi platelet ringan. Iloprost tersedia dalam bentuk inhalasi. Efek sampingnya adalah batuk, mual, muntah, nyeri kepala dan nyeri rahang. (in)
L'Iloprost è il nome del principio attivo di indicazione specifica contro l'ipertensione polmonare per la sua proprietà vasodilatatrice e di inibizione dell'aggregazione piastrinica.È un composto chimico sintetizzato nel corso degli anni 1980 ed è stato approvato dall'FDA nel 2004 per coloro che soffrono di PAH (pulmonary arterial hypertension - ipertensione arteriosa polmonare).L'Iloprost è prodotto dalla casa farmaceutica Italfarmaco e venduto con il brand Ventavis. (it)
Iloprost is een medicijn dat, afhankelijk van de toedieningsvorm, wordt toegepast voor de behandeling van onder andere pulmonale arteriële hypertensie (PAH), de ziekte van Buerger en ischemie in de extremiteiten. Het wordt in Europa op de markt gebracht door Bayer Schering Pharma AG. (nl)
Iloprosta é um medicamento usado para tratar a hipertensão arterial pulmonar (HAP), escleroderma e fenômeno de Raynaud. (pt)
Ілопрост (МНН: Iloprost) — синтетичний аналог простацикліну I2, взаємодіє з простагландиновими рецепторами PTGER1, PTGER2, PTGER3, PTGER4. Інгібітори тромбоксану. Належить до групи антиагрегантів, ATX — B01A C11 Ілопрост (uk)

dbo:alternativeName

Ventavis, Ilomedine (en)

dbo:casNumber

78919-13-8

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236025

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DB01088

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JED5K35YGL

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D02721

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a612032

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5311181

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wiki-commons:Special:FilePath/Iloprost_2D_structure.svg?width=300

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B01 (en)

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AC11 (en)

dbp:bioavailability

The absolute bioavailability of inhaled iloprost has not been determined. (en)

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22 (xsd:integer)

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Iloprost (en)

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DB01088 (en)

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-1800.0

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32 (xsd:integer)

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D02721 (en)

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Rx-only (en)

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Rx-only (en)

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Rx-only (en)

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yes (en)

dbp:licenceUs

Iloprost (en)

dbp:medlineplus

a612032 (en)

dbp:metabolism

Iloprost is metabolized principally via β-oxidation of the carboxyl side chain. The main metabolite is tetranor-iloprost, which is found in the urine in free and conjugated form. In animal experiments, tetranor-iloprost was pharmacologically inactive. (en)

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Ventavis, Ilomedine (en)

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JED5K35YGL (en)

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إيلوبروست (Iloprost) تركيبه الكيميائي إلوبروست تروميثامين، ، ويؤثر على تراكم الصفائح الدموية. (ar)
Iloprost is a medication used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and other diseases in which the blood vessels are constricted and blood cannot flow to the tissues. This damages the tissues and causes high blood pressure. There is ongoing research into using it as a frostbite treatment. Iloprost works by opening (dilating) the blood vessels to allow the blood to flow through again. It was developed by the pharmaceutical company Schering AG and is marketed by Bayer Schering Pharma AG in Europe and Actelion Pharmaceuticals in the USA. Iloprost is given via inhalation, and a therapeautic benefit of the drug is that a very low dose is required because of the deposition in the lung. Iloprost has few systemic side effects for that reason. (en)
El iloprost es un análogo sintético de la prostaciclina administrado por vía inhalada para mejorar los síntomas hemodinámicos de la hipertensión pulmonar. Se ha estudiado para el uso preventivo de lesiones por reperfusión. Otros análogos de la prostaciclina son administrados por vía subcutánea (treprostinil) u oral (beraprost). (es)
L'iloprost est une molécule analogue de la prostacycline, développé par Actelion, utilisé comme médicament administré par inhalation dans l'hypertension artérielle pulmonaire de classe III ou IV. (fr)
Iloprost adalah obat golongan analog prostasiklin yang digunakan untuk mengobati hipertensi paru. Iloprost bekerja dengan cara relaksasi otot polos pembuluh darah dan menyebabkan vasodilatasi. Penggunaan jangka panjangnya akan mempengaruhi tahanan vaskular pembuluh darah dan menekan proliferasi otot polos pembuluh darah. Iloprost juga memiliki efek inhibitor agregasi platelet ringan. Iloprost tersedia dalam bentuk inhalasi. Efek sampingnya adalah batuk, mual, muntah, nyeri kepala dan nyeri rahang. (in)
L'Iloprost è il nome del principio attivo di indicazione specifica contro l'ipertensione polmonare per la sua proprietà vasodilatatrice e di inibizione dell'aggregazione piastrinica.È un composto chimico sintetizzato nel corso degli anni 1980 ed è stato approvato dall'FDA nel 2004 per coloro che soffrono di PAH (pulmonary arterial hypertension - ipertensione arteriosa polmonare).L'Iloprost è prodotto dalla casa farmaceutica Italfarmaco e venduto con il brand Ventavis. (it)
Iloprost is een medicijn dat, afhankelijk van de toedieningsvorm, wordt toegepast voor de behandeling van onder andere pulmonale arteriële hypertensie (PAH), de ziekte van Buerger en ischemie in de extremiteiten. Het wordt in Europa op de markt gebracht door Bayer Schering Pharma AG. (nl)
Iloprosta é um medicamento usado para tratar a hipertensão arterial pulmonar (HAP), escleroderma e fenômeno de Raynaud. (pt)
Ілопрост (МНН: Iloprost) — синтетичний аналог простацикліну I2, взаємодіє з простагландиновими рецепторами PTGER1, PTGER2, PTGER3, PTGER4. Інгібітори тромбоксану. Належить до групи антиагрегантів, ATX — B01A C11 Ілопрост (uk)

rdfs:label

إيلوبروست (ar)
Iloprost (es)
Iloprost (fr)
Iloprost (en)
Iloprost (in)
Iloprost (it)
Iloprost (nl)
Iloprosta (pt)
Ілопрост (uk)

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wikipedia-en:Iloprost?oldid=1089868243&ns=0

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wikipedia-en:Iloprost

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wikipedia-en:Iloprost