Kasugamycin (original) (raw)
Kasugamycin ist ein Aminoglycosid-Antibiotikum, welches aus isoliert wurde. Kasugamycin wirkt durch Hemmung der 50S-Untereinheit bakterieller Ribosome und somit der Proteinbiosynthese. Es wurde 1965 durch Hamao Umezawa, der auch Kanamycin und Bleomycin entdeckt hatte, gefunden.
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| dbo:abstract | Kasugamycin ist ein Aminoglycosid-Antibiotikum, welches aus isoliert wurde. Kasugamycin wirkt durch Hemmung der 50S-Untereinheit bakterieller Ribosome und somit der Proteinbiosynthese. Es wurde 1965 durch Hamao Umezawa, der auch Kanamycin und Bleomycin entdeckt hatte, gefunden. (de) La kasugamycine est un aminoglycoside qui possède des propriétés antifongiques et antibactériennes. La kasugamycine se fixe à l'ARN ribosomique de la petite sous-unité du ribosome. Elle bloque ainsi la formation du complexe de démarrage de la traduction qui implique la fixation de l'ARNt porteur de fmet (méthionine formylée) au niveau de l'ARNm. Comme la plupart des aminoglycosides, la kasugamycine est un produit naturel issu du métabolisme secondaire des bactéries actinomycètes. Elle a été découverte en 1965 par Hamao Umezawa, qui l'a extraite de la bactérie . (fr) Kasugamycin (Ksg) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin was discovered by Hamao Umezawa, who also discovered kanamycin and bleomycin, as a drug that prevent growth of a fungus causing rice blast disease. It was later found to inhibit bacterial growth also. It exists as a white, crystalline substance with the chemical formula C14H28ClN3O10 (kasugamycin hydrochloride). It is also known as kasumin. (en) カスガマイシン（英 Kasugamycin）は抗生物質の一種で、主に農業用殺菌剤として利用される。CAS番号は6980-18-3。 (ja) |
| dbo:alternativeName | Kasumin; 3-O-[2-Amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-(D)-arabino-hexopyranosyl]-(D)-chiro-inositol (en) |
| dbo:iupacName | 2-amino-2-[(2R,3S,5S,6R)-5-amino-2-methyl-6-[(2R,3S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxyoxan-3-yl]iminoacetic acid (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/Kasugamycin_structure.svg?width=300 |
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| dbo:wikiPageLength | 7214 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1095845338 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Aminoglycoside dbc:Aminoglycoside_antibiotics dbr:Mutation dbr:Methylation dbr:Bleomycin dbr:Antibiotic dbr:Kanamycin dbr:MRNA dbr:Transfer_RNA dbr:Streptomyces dbr:Hamao_Umezawa dbr:Protein dbr:Japan dbr:Hydrochloride dbr:Kasuga-taisha dbr:Translation_(biology) dbr:Nara,_Nara dbr:X-ray_crystallography dbr:Methyltransferase dbr:Ribosome dbr:Ribosomal_RNA dbr:Streptomyces_kasugaensis |
| dbp:imagefile | Kasugamycin structure.svg (en) |
| dbp:imagesize | 200 (xsd:integer) |
| dbp:iupacname | 2 (xsd:integer) |
| dbp:othernames | Kasumin; 3-O-[2-Amino-4-[amino]-2,3,4,6-tetradeoxy-(D)-arabino-hexopyranosyl]-(D)-chiro-inositol (en) |
| dbp:verifiedfields | changed (en) |
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| dbp:watchedfields | changed (en) |
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| dcterms:subject | dbc:Aminoglycoside_antibiotics |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 yago:WikicatAminoglycosideAntibiotics yago:Agent114778436 yago:Antibacterial102716205 yago:Antibiotic102716866 yago:CausalAgent100007347 yago:Drug103247620 yago:Matter100020827 yago:Medicine103740161 yago:PhysicalEntity100001930 dbo:ChemicalCompound yago:Substance100020090 umbel-rc:ChemicalSubstanceType |
| rdfs:comment | Kasugamycin ist ein Aminoglycosid-Antibiotikum, welches aus isoliert wurde. Kasugamycin wirkt durch Hemmung der 50S-Untereinheit bakterieller Ribosome und somit der Proteinbiosynthese. Es wurde 1965 durch Hamao Umezawa, der auch Kanamycin und Bleomycin entdeckt hatte, gefunden. (de) La kasugamycine est un aminoglycoside qui possède des propriétés antifongiques et antibactériennes. La kasugamycine se fixe à l'ARN ribosomique de la petite sous-unité du ribosome. Elle bloque ainsi la formation du complexe de démarrage de la traduction qui implique la fixation de l'ARNt porteur de fmet (méthionine formylée) au niveau de l'ARNm. Comme la plupart des aminoglycosides, la kasugamycine est un produit naturel issu du métabolisme secondaire des bactéries actinomycètes. Elle a été découverte en 1965 par Hamao Umezawa, qui l'a extraite de la bactérie . (fr) Kasugamycin (Ksg) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin was discovered by Hamao Umezawa, who also discovered kanamycin and bleomycin, as a drug that prevent growth of a fungus causing rice blast disease. It was later found to inhibit bacterial growth also. It exists as a white, crystalline substance with the chemical formula C14H28ClN3O10 (kasugamycin hydrochloride). It is also known as kasumin. (en) カスガマイシン（英 Kasugamycin）は抗生物質の一種で、主に農業用殺菌剤として利用される。CAS番号は6980-18-3。 (ja) |
| rdfs:label | Kasugamycin (de) Kasugamycine (fr) Kasugamycin (en) カスガマイシン (ja) |
| owl:sameAs | freebase:Kasugamycin yago-res:Kasugamycin wikidata:Kasugamycin wikidata:Kasugamycin http://azb.dbpedia.org/resource/کازوقامایسین dbpedia-de:Kasugamycin dbpedia-fa:Kasugamycin dbpedia-fr:Kasugamycin dbpedia-ja:Kasugamycin dbpedia-sh:Kasugamycin dbpedia-sr:Kasugamycin https://global.dbpedia.org/id/2xhdH |
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