Killer yeast (original) (raw)
A killer yeast is a yeast, such as Saccharomyces cerevisiae, which is able to secrete one of a number of toxic proteins which are lethal to susceptible cells. These "killer toxins" are polypeptides that kill sensitive cells of the same or related species, often functioning by creating pores in target cell membranes. These yeast cells are immune to the toxic effects of the protein due to an intrinsic immunity. Killer yeast strains can be a problem in commercial processing because they can kill desirable strains. The killer yeast system was first described in 1963. Study of killer toxins helped to better understand the secretion pathway of yeast, which is similar to those of more complex eukaryotes. It also can be used in treatment of some diseases, mainly those caused by fungi.
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| dbo:abstract | El efecto killer consiste en la secreción de una toxina de carácter proteico por parte de unas determinadas cepas de levaduras, que provoca la muerte celular de levaduras denominadas "sensibles". Las levaduras killer (asesino en inglés) no se ven afectadas por la toxina secretada por sí mismas, pero sí pueden ser afectadas por otras toxinas. Las levaduras pueden ser del fenotipo killer (K), del fenotipo sensible (S), o del fenotipo neutro (N). Estas últimas no producen la toxina, pero son capaces de resistir sus efectos. Los determinantes genéticos asociados al carácter killer en levaduras, son a la vez citoplásmicos, y nucleares. En Saccharomyces cerevisiae se debe a la presencia en el citoplasma de partículas de tipo viral. La producción de estas micotoxinas está asociada a la presencia de partículas de doble cadena lineal de ARN. (es) A killer yeast is a yeast, such as Saccharomyces cerevisiae, which is able to secrete one of a number of toxic proteins which are lethal to susceptible cells. These "killer toxins" are polypeptides that kill sensitive cells of the same or related species, often functioning by creating pores in target cell membranes. These yeast cells are immune to the toxic effects of the protein due to an intrinsic immunity. Killer yeast strains can be a problem in commercial processing because they can kill desirable strains. The killer yeast system was first described in 1963. Study of killer toxins helped to better understand the secretion pathway of yeast, which is similar to those of more complex eukaryotes. It also can be used in treatment of some diseases, mainly those caused by fungi. (en) |
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| rdfs:comment | A killer yeast is a yeast, such as Saccharomyces cerevisiae, which is able to secrete one of a number of toxic proteins which are lethal to susceptible cells. These "killer toxins" are polypeptides that kill sensitive cells of the same or related species, often functioning by creating pores in target cell membranes. These yeast cells are immune to the toxic effects of the protein due to an intrinsic immunity. Killer yeast strains can be a problem in commercial processing because they can kill desirable strains. The killer yeast system was first described in 1963. Study of killer toxins helped to better understand the secretion pathway of yeast, which is similar to those of more complex eukaryotes. It also can be used in treatment of some diseases, mainly those caused by fungi. (en) El efecto killer consiste en la secreción de una toxina de carácter proteico por parte de unas determinadas cepas de levaduras, que provoca la muerte celular de levaduras denominadas "sensibles". Las levaduras killer (asesino en inglés) no se ven afectadas por la toxina secretada por sí mismas, pero sí pueden ser afectadas por otras toxinas. Las levaduras pueden ser del fenotipo killer (K), del fenotipo sensible (S), o del fenotipo neutro (N). Estas últimas no producen la toxina, pero son capaces de resistir sus efectos. (es) |
| rdfs:label | Efecto killer (es) Killer yeast (en) |
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