Lamin B1 (original) (raw)
Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure, and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Lamin B, along with heterochromatin, is anchored to the inner surface of the nuclear membrane by the lamin B receptor.
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| dbo:abstract | Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure, and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Lamin B, along with heterochromatin, is anchored to the inner surface of the nuclear membrane by the lamin B receptor. (en) Ламін B1 (англ. Lamin B1) – білок, який кодується геном LMNB1, розташованим у людей на короткому плечі 5-ї хромосоми. Довжина поліпептидного ланцюга білка становить 586 амінокислот, а молекулярна маса — 66 408. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин Локалізований у ядрі, мембрані. (uk) |
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| dbo:wikiPageWikiLink | dbr:Protein-protein_interaction dbr:Gene dbr:Lamin_B2 dbr:Lamin_B_receptor dbr:Protein dbr:Heterochromatin dbr:Thymopoietin dbr:Nuclear_membrane dbr:Autosomal_dominant_adult-onset_demyelinating_leukodystrophy |
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| gold:hypernym | dbr:Protein |
| rdf:type | owl:Thing dbo:Biomolecule dbo:Gene wikidata:Q206229 wikidata:Q7187 dbo:HumanGene dbo:Protein |
| rdfs:comment | Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure, and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Lamin B, along with heterochromatin, is anchored to the inner surface of the nuclear membrane by the lamin B receptor. (en) Ламін B1 (англ. Lamin B1) – білок, який кодується геном LMNB1, розташованим у людей на короткому плечі 5-ї хромосоми. Довжина поліпептидного ланцюга білка становить 586 амінокислот, а молекулярна маса — 66 408. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин Локалізований у ядрі, мембрані. (uk) |
| rdfs:label | Lamin B1 (en) Ламін B1 (uk) |
| owl:sameAs | freebase:Lamin B1 wikidata:Lamin B1 dbpedia-cy:Lamin B1 dbpedia-uk:Lamin B1 https://global.dbpedia.org/id/jgjz |
| prov:wasDerivedFrom | wikipedia-en:Lamin_B1?oldid=1116588424&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Lamin_B1 |
| is dbo:wikiPageRedirects of | dbr:LMNB1 dbr:LMNB1_(gene) |
| is dbo:wikiPageWikiLink of | dbr:Intermediate_filament dbr:LMNB1 dbr:LMNB1_(gene) dbr:Lamin dbr:Telophase dbr:MAP1LC3B dbr:SmURFP |
| is foaf:primaryTopic of | wikipedia-en:Lamin_B1 |