Leiden Open Variation Database (original) (raw)
The Leiden Open Variation Database (LOVD) is a free, flexible web-based open source database developed in the Leiden University Medical Center in the Netherlands, designed to collect and display variants in the DNA sequence. The focus of an LOVD is usually the combination between a gene and a genetic (heritable) disease. All sequence variants found in individuals are collected in the database, together with information about whether they could be causally connected to the disease (i.e. a disease-causing variant or mutation) or not (i.e. a non-disease causing variant). Specialized doctors (clinical geneticists) use LOVDs to diagnose and advise patients carrying a genetic disease. Ideally, if a patient has been screened for mutations and one has been found, information in LOVD can predict th
| Property | Value |
|---|---|
| dbo:abstract | The Leiden Open Variation Database (LOVD) is a free, flexible web-based open source database developed in the Leiden University Medical Center in the Netherlands, designed to collect and display variants in the DNA sequence. The focus of an LOVD is usually the combination between a gene and a genetic (heritable) disease. All sequence variants found in individuals are collected in the database, together with information about whether they could be causally connected to the disease (i.e. a disease-causing variant or mutation) or not (i.e. a non-disease causing variant). Specialized doctors (clinical geneticists) use LOVDs to diagnose and advise patients carrying a genetic disease. Ideally, if a patient has been screened for mutations and one has been found, information in LOVD can predict the progress of the disease. In contrast to human genome databases, showing information on all DNA variants, LOVDs include information about the individuals in which the variants were found. This patient information is usually only accessible for registered users. Currently, LOVD installations worldwide contain more than 515,500 variant observations (124,000 unique variants in 5175 genes) in 162,000 patients. (en) |
| dbo:wikiPageExternalLink | http://www.lovd.nl/3.0/home |
| dbo:wikiPageID | 24127822 (xsd:integer) |
| dbo:wikiPageLength | 5970 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1077289931 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Mutation dbr:Next-generation_sequencing dbr:Human_genome_project dbc:Population_genetics_organizations dbr:Open_source dbr:Gene dbr:MySQL dbr:Leiden_University_Medical_Center dbr:Mutalyzer dbc:Cross-platform_free_software dbr:GEN2PHEN dbc:Genetics_databases dbr:PHP dbr:Platform-independent dbr:Genetic_disease dbr:Clinical_geneticist |
| dbp:wikiPageUsesTemplate | dbt:Reflist |
| dcterms:subject | dbc:Population_genetics_organizations dbc:Cross-platform_free_software dbc:Genetics_databases |
| gold:hypernym | dbr:Database |
| rdf:type | dbo:BiologicalDatabase |
| rdfs:comment | The Leiden Open Variation Database (LOVD) is a free, flexible web-based open source database developed in the Leiden University Medical Center in the Netherlands, designed to collect and display variants in the DNA sequence. The focus of an LOVD is usually the combination between a gene and a genetic (heritable) disease. All sequence variants found in individuals are collected in the database, together with information about whether they could be causally connected to the disease (i.e. a disease-causing variant or mutation) or not (i.e. a non-disease causing variant). Specialized doctors (clinical geneticists) use LOVDs to diagnose and advise patients carrying a genetic disease. Ideally, if a patient has been screened for mutations and one has been found, information in LOVD can predict th (en) |
| rdfs:label | Leiden Open Variation Database (en) |
| owl:sameAs | freebase:Leiden Open Variation Database wikidata:Leiden Open Variation Database http://bs.dbpedia.org/resource/Leiden_Open_Variation_baza_podataka https://global.dbpedia.org/id/cbTK |
| prov:wasDerivedFrom | wikipedia-en:Leiden_Open_Variation_Database?oldid=1077289931&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Leiden_Open_Variation_Database |
| is dbo:wikiPageRedirects of | dbr:LOVD |
| is dbo:wikiPageWikiLink of | dbr:GEN2PHEN dbr:LOVD |
| is foaf:primaryTopic of | wikipedia-en:Leiden_Open_Variation_Database |